Water,
Год журнала:
2024,
Номер
16(24), С. 3712 - 3712
Опубликована: Дек. 23, 2024
This
study
aimed
to
investigate
the
distribution
of
commonly
used
pesticides
and
their
metabolites
in
drinking
water
before
after
treatment
at
plants
(DWTPs)
Yangtze
River
Delta
assess
health
risks
from
perspective
non-carcinogenicity
carcinogenicity.
A
total
85
were
analyzed
source,
finished,
tap
using
online
solid-phase
extraction
coupled
with
liquid
chromatography–tandem
mass
spectrometry.
Across
91
samples,
31
parent
compounds
9
detected,
median
concentrations
62.2
(range:
6.20
392)
ng/L.
Atrazine,
2-hydroxyatrazine,
S-metolachlor
detected
all
samples.
Advanced
processes
DWTPs
effectively
reduced
residues
(removal
rates
51.5~95.2%),
removal
for
significantly
lower
than
those
(p
=
0.03).
Regarding
risks,
estimated
carcinogenic
risk
was
within
acceptable
limits
non-carcinogenic
insignificant.
However,
it
is
important
note
that
both
two
relatively
highest
are
pesticide
metabolites.
Overall,
this
showed
despite
dozens
being
Delta,
assessed
be
The
effectiveness
current
advanced
treatments
removing
indicates
necessity
technique
improvement
DWTPs.
Environment & Health,
Год журнала:
2024,
Номер
2(6), С. 332 - 349
Опубликована: Фев. 28, 2024
In
recent
years,
rapid
industrial
development
has
resulted
in
the
production
and
exposure
of
a
substantial
number
compounds
to
human
body.
This
created
an
urgent
need
environmental
toxicology
for
models
that
are
efficient,
accurate,
cost-effective
evaluating
health
impacts
these
on
humans.
Over
past
seven
decades,
various
cancer
cell
lines
immortalized
have
made
significant
contributions
advancement
research
organ
toxicity.
Pluripotent
stem
technology,
especially
toxicological
derived
from
pluripotent
cells,
presents
modern
toxicologists
with
high-throughput,
species-relevant,
predictive
options.
this
comprehensive
review,
we
assess
characteristics
representative
toxicology,
as
well
introduce
two
distinct
types
their
innovative
models.
We
explore
applications
prospects
field
while
also
addressing
readiness
vitro
confront
emerging
challenges
future.
Journal of Toxicology and Environmental Health Part B,
Год журнала:
2025,
Номер
unknown, С. 1 - 40
Опубликована: Фев. 27, 2025
Atrazine
is
a
chlorotriazine
herbicide
that
one
of
the
most
widely
used
herbicides
in
USA
and
world.
For
over
60
years
atrazine
has
been
on
major
crops
including
corn,
sorghum,
sugarcane
to
control
broadleaf
grassy
weed
emergence
growth.
exerted
economic
environmental
impact
time,
resulting
reduced
production
costs
increased
conservation
tillage
practices.
However,
widespread
use
long
half-life
led
high
prevalence
environment.
Indeed,
frequent
contaminant
detected
water
sources
USA.
Due
its
almost
ubiquitous
presence
questions
regarding
safety,
well-studied.
First
reported
affect
reproduction
with
potential
disruptive
effects
which
were
later
linked
immune
system,
cancer,
stress
response,
neurological
disorders,
cardiovascular
ailments
experimental
models.
multiple
interwoven
systems
broadens
significance
exposure.
The
endeavor
uncover
mechanisms
underlying
atrazine-induced
dysfunction
mammals
ongoing,
new
genetic
pharmacological
targets
being
reported.
This
review
aims
summarize
prominent
mammalian
physiology,
primarily
focusing
empirical
studies
conducted
lab
animal
models
establish
correlations
epidemiological
human
when
relevant.
In
addition,
current
common
patterns
toxicity
action
will
be
examined.
Journal of Agricultural and Food Chemistry,
Год журнала:
2024,
Номер
72(40), С. 21959 - 21972
Опубликована: Сен. 27, 2024
Pesticides
are
extensively
utilized
in
contemporary
agriculture
to
manage
pests,
enhance
crop
yields,
and
sustain
productivity.
Nevertheless,
the
persistent
herbicide
represents
a
dual-edged
weapon.
On
one
hand,
their
prolonged
efficacy
enables
reduced
application
frequency
during
growth
seasons,
resulting
cost
savings
on
labor.
However,
presence
of
these
residues
within
fields
poses
safety
risks
soil
quality,
sensitive
crops
subsequent
rotations,
agricultural
product
ecological
environment.
This
review
presents
comprehensive
mechanisms
action,
risks,
ecotoxicology,
residue
analysis
methods
nine
representative
herbicides
(namely,
atrazine,
imazethapyr,
imazapic,
mesosulfuron-methyl,
halosulfuron-methyl,
fomesafen,
diflufenican,
quinclorac,
pyroxasulfone).
The
objective
is
guide
scientific
rational
utilization
practices
while
minimizing
phytotoxicity
effectively
monitoring
controlling
pollution.
These
can
not
only
provide
practical
recommendations
for
mitigating
potential
plant
toxicity
environmental
but
also
contribute
valuable
technical
insights
efficient
pollution
prevention.
Additionally,
unaddressed
research
objectives
were
anticipated.
