How far do we still need to go with antibiotics in aquatic environments? Antibiotic occurrence, chemical-free or chemical-limited strategies, key challenges, and future perspectives
Water Research,
Год журнала:
2025,
Номер
unknown, С. 123179 - 123179
Опубликована: Янв. 1, 2025
Язык: Английский
Environmental Applications of Mass Spectrometry for Emerging Contaminants
Molecules,
Год журнала:
2025,
Номер
30(2), С. 364 - 364
Опубликована: Янв. 17, 2025
Emerging
contaminants
(ECs),
encompassing
pharmaceuticals,
personal
care
products,
pesticides,
and
industrial
chemicals,
represent
a
growing
threat
to
ecosystems
human
health
due
their
persistence,
bioaccumulation
potential,
often-unknown
toxicological
profiles.
Addressing
these
challenges
necessitates
advanced
analytical
tools
capable
of
detecting
quantifying
trace
levels
ECs
in
complex
environmental
matrices.
This
review
highlights
the
pivotal
role
mass
spectrometry
(MS)
monitoring
ECs,
emphasizing
its
high
sensitivity,
specificity,
versatility
across
various
techniques
such
as
Gas
Chromatography-Mass
Spectrometry
(GC-MS),
Liquid
(LC-MS),
High-Resolution
Mass
(HR-MS).
The
application
MS
has
facilitated
real-time
detection
volatile
organic
compounds,
comprehensive
non-targeted
screening
unknown
contaminants,
accurate
quantification
diverse
matrices
including
water,
soil,
air.
Despite
effectiveness,
matrix
interferences,
lack
standardized
methodologies,
limited
spectral
libraries
persist.
However,
recent
advancements,
hybrid
systems
integration
artificial
intelligence
(AI),
are
paving
way
for
more
efficient
predictive
modeling
contaminant
behavior.
Continued
innovation
technologies
collaborative
efforts
essential
overcome
existing
ensure
sustainable
solutions
mitigating
risks
associated
with
emerging
contaminants.
Язык: Английский
Optimization of Capillary Electrophoresis by Central Composite Design for Separation of Pharmaceutical Contaminants in Water Quality Testing
Environments,
Год журнала:
2025,
Номер
12(1), С. 22 - 22
Опубликована: Янв. 12, 2025
Many
pharmaceutical
active
compounds
are
prepared
as
hydrochlorides
for
quick
release
in
the
gastrointestinal
tract
upon
oral
administration.
Their
inadvertent
escape
into
water
environment
requires
efficient
analytical
separation
accurate
quantitation
to
monitor
their
environmental
fate.
The
purpose
of
this
study
is
demonstrate
how
best
optimize
a
capillary
electrophoresis
method
four
model
hydrochlorides.
Concentration
sodium
dibasic
phosphate
background
electrolyte
solution,
pH
adjustment
with
HCl
or
NaOH,
and
applied
voltage
across
were
three
key
factors
chosen
optimization.
peak
resolutions
total
migration
time
examined
response
indicators
complete
central
composite
design
surface
methodology.
examination
revealed
that
CE
was
driven
significantly
by
linear
regression
minimally
quadratic
model,
based
on
coefficient
determination,
lack
fit,
sum
squares,
p
values.
Under
optimal
conditions
concentration
75
mM,
9,
10
kV,
separated
within
five
minutes
order
metformin
(first)
>
phenformin
mexiletine
ranitidine
(last).
limits
UV
detection/quantification
attained
under
0.015/0.045,
0.020/0.060,
0.142/0.426,
0.017/0.051,
respectively.
Язык: Английский
High-Throughput Solid Phase Extraction for Targeted and Nontargeted Exposomics
Analytical Chemistry,
Год журнала:
2025,
Номер
unknown
Опубликована: Март 13, 2025
Characterizing
the
chemical
exposome
relies
on
advanced
instrumentation
including
tandem
mass
spectrometry
coupled
to
liquid
chromatography
(LC-MS/MS),
and
nontargeted
analysis
(NTA)
using
high-resolution
MS.
However,
proper
sample
pretreatment,
balancing
broad
analyte
coverage,
method
robustness,
throughput
remain
a
major
bottleneck
in
exposomics.
Here,
we
developed
robust
scalable
solid
phase
extraction
(SPE)
protocol
for
human
urine
plasma
optimized
it
panel
of
94
highly
diverse
environmental
food-related
contaminants
(LogP
−0.7
6.8).
Extraction
recoveries
(RE)
signal
suppression
enhancement
(SSE)
were
determined
targeted
LC-MS/MS.
Acceptable
REs
(60–140%)
achieved
>70%
analytes,
acceptable
SSE
values
86%
90%
plasma,
respectively.
Subsequently,
was
transferred
96-well
plate
format,
significantly
improving
meet
capacity
requirements
needed
exposome-wide
association
studies
(ExWAS).
The
established
workflow
is
approximately
10×
faster
than
routinely
used
metabolomics-based
protein
precipitation
approaches
when
comparing
estimated
total
time
1000
samples.
method's
applicability
NTA
suspect
screening
tested
compared
generic
NIST
standard
reference
materials
(SRM
3672)
1950).
Favorable
performance
shown
while
SPE
demonstrated
promising
results.
thus
not
only
superior
future
high-throughput
exposomics
but
also
offers
an
option
applications.
presented
well-balanced
approach
applicable
research
fields
pharmacology,
food
safety,
systems
toxicology.
Язык: Английский
Nontargeted screening of contaminants of emerging concern in the Nandu River Estuary
Marine Pollution Bulletin,
Год журнала:
2025,
Номер
215, С. 117870 - 117870
Опубликована: Март 28, 2025
Язык: Английский
Photochemical transformation of benzalkonium chloride in seawater
Journal of Hazardous Materials,
Год журнала:
2025,
Номер
493, С. 138312 - 138312
Опубликована: Апрель 18, 2025
Язык: Английский
Identification of Omitted Pollutants in Environmental Water via In Situ Thin-Film Microextraction
Analytical Chemistry,
Год журнала:
2024,
Номер
unknown
Опубликована: Сен. 15, 2024
Sample
preparation
is
an
inevitable
step
in
the
screening
workflow
for
identification
of
unknown
pollutants
aquatic
environment.
However,
possible
loss
during
sample
has
aroused
serious
concern
but
remains
not
effectively
resolved.
This
study
shows
that
high-risk
omitted
solid-phase
extraction
(SPE)
can
be
identified
via
situ
thin-film
microextraction
(TFME)
coupled
with
high-resolution
mass
spectrometry.
It
was
observed
a
total
541
features
showed
higher
spectrometry
signal
intensity
by
using
TFME
comparison
SPE.
Subsequently,
28
compounds
were
from
comparing
recorded
tandem
spectra
online
database
and
validating
standards.
Notably,
six
out
these
completely
SPE,
including
dye,
drug,
industrial
product.
confirmed
lower
efficiencies
SPE
attributed
to
limited
volumes,
losses
transportation
storage,
entrapment
columns.
demonstrates
should
used
as
supplementary
technique
extending
coverage
workflows.
Язык: Английский
Contamination with Pharmaceuticals in Aquatic Environment: Focus on Analytical Methodologies
Applied Sciences,
Год журнала:
2024,
Номер
14(19), С. 8645 - 8645
Опубликована: Сен. 25, 2024
The
growing
prevalence
of
pharmaceutical
compounds
in
the
environment
raises
significant
concerns
due
to
their
potential
impacts
on
ecological
and
human
health.
This
present
manuscript
focuses
methods
used
extract
determine
these
pharmaceuticals
water
samples.
It
provides
a
comprehensive
analysis
extraction
techniques
analytical
approaches
employed
for
identification
quantification
environmental
water.
Due
chemical
properties
widespread
use,
persist
contaminate
bodies,
soil,
sediments.
presence
aquatic
has
been
linked
several
adverse
effects
organisms,
including
disruption
physiological
processes
reproductive
impairment.
Furthermore,
can
affect
health
through
food
drinking
contamination
contribute
antibiotic
resistance.
contaminants
samples
presents
challenges
complex
matrix
low
concentrations
target
substances.
Various
sample
preparation
protocols,
solid-phase
(more
than
76%
studied
literature)
QuEChERS
(quick,
easy,
cheap,
effective,
rugged,
safe),
coupled
with
liquid
chromatography–tandem-mass
spectrometry,
are
commonly
determination.
These
offer
high
sensitivity,
selectivity,
efficiency
identifying
quantifying
is,
therefore,
essential
that
ongoing
research
is
conducted
order
develop
more
efficient
mitigation
strategies
address
effectively.
also
crucial
increased
awareness
regulatory
measures
put
place
minimize
risks
associated
pollutants.
Язык: Английский
Hydrophilic-lipophilic balance copolymer composite nanofiber as an adsorbent for online solid phase extraction of three estrogens from water samples with column-switching prior to high-performance liquid chromatography
Analytica Chimica Acta,
Год журнала:
2024,
Номер
1335, С. 343456 - 343456
Опубликована: Ноя. 21, 2024
Язык: Английский