Micro/nano-plastics impacts in cardiovascular systems across species

The Science of The Total Environment, Год журнала: 2024, Номер 942, С. 173770 - 173770

Опубликована: Июнь 7, 2024

Язык: Английский

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Meta-analysis of the Effects of Microplastic on Fish: Insights into Growth, Survival, Reproduction, Oxidative Stress, and Gut Microbiota Diversity

Water Research, Год журнала: 2024, Номер 267, С. 122493 - 122493

Опубликована: Сен. 21, 2024

Язык: Английский

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Polystyrene Nanoplastics Hitch-Hike the Gut–Brain Axis to Exacerbate Parkinson’s Pathology

ACS Nano, Год журнала: 2025, Номер unknown

Опубликована: Янв. 30, 2025

The neurological implications of micro- and nanoplastic exposure have recently come under scrutiny due to the environmental prevalence these synthetic materials. Parkinson's disease (PD) is a major disorder clinically characterized by intracellular Lewy-body inclusions dopaminergic neuronal death. These pathological hallmarks PD, according Braak's hypothesis, are mediated afferent propagation α synuclein (αS) via enteric nervous system, or so-called gut-brain axis. Here we first examined effect polystyrene nanoplastics on peripheral central pathogenesis A53T, representative αS mutant. Specifically, accelerated amyloid aggregation A53T αS, which subsequently elevated in vitro production glial activation biomarkers, cytokines, reactive oxygen species compromised mitochondrial lysosomal membrane integrity, further shifting cellular metabolite profiles association with PD pathophysiology. In vivo, coadministration facilitated their synergistic gut-to-brain transmission mice, leading progressive impairment physical motor skills resemblance characteristic symptoms. This study provides insights into response vulnerability axis nanoplastics.

Язык: Английский

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An evaluation of microplastic contamination in the marine waters and species in the coastal region of the South Yellow Sea, China

Journal of Hazardous Materials, Год журнала: 2024, Номер 469, С. 134018 - 134018

Опубликована: Март 13, 2024

Язык: Английский

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Integrin A5B1-mediated endocytosis of polystyrene nanoplastics: Implications for human lung disease and therapeutic targets

The Science of The Total Environment, Год журнала: 2024, Номер 953, С. 176017 - 176017

Опубликована: Сен. 3, 2024

Язык: Английский

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Trade-offs and synergies pattern evolution of ecosystem structure-resilience-activity-services (SRAS) in the Belt and Road Initiative region

Resources Conservation and Recycling, Год журнала: 2024, Номер 211, С. 107883 - 107883

Опубликована: Сен. 4, 2024

Язык: Английский

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Microplastics in the benthic fish from the Canadian St. Lawrence River and Estuary: Occurrence, spatial distribution and ecological risk assessment

Marine Pollution Bulletin, Год журнала: 2025, Номер 212, С. 117509 - 117509

Опубликована: Янв. 6, 2025

Microplastic contamination in the St. Lawrence River and Estuary (SLRE), Canada, poses potential risks to aquatic species. However, limited understanding of microplastic benthic fish, potentially more vulnerable than pelagic species, impedes effective risk assessment this crucial ecosystem. This study addressed knowledge gaps by analyzing microplastics gastrointestinal tracts (GIT) gills Channel Catfish (Ictalurus punctatus) Atlantic Tomcod (Microgadus tomcod) SLRE. Forty-two fish from ten stations were examined using KOH digestion, density separation, wet-peroxidation, spectroscopy. Results indicated an average abundance 3.0 ± 0.4 (mean SE) particles per individual fish. Most detected small (<809 μm) fibers, with blue transparent colors. Major polymers identified included polyethylene terephthalate polyethylene. While catfish showed higher abundances tomcod, data based on GIT weight do not support biomagnification predator-prey relationship. downstream Québec City elevated levels variations their characteristics compared found a site located 50 km upstream. Urban activity may increase accumulation others. highlights need for further studies migratory capacities Ecological revealed medium high-risks close due prevalence smaller <809 μm highly toxic (polymethyl methacrylate, polyvinylchloride, polyurethane, acrylonitrile butadiene styrene). provides baseline monitoring plastic pollution SLRE assessing ecological risks.

Язык: Английский

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Intestinal Barrier Damage and Growth Retardation Caused by Exposure to Polystyrene Nanoplastics Through Lactation Milk in Developing Mice

Nanomaterials, Год журнала: 2025, Номер 15(1), С. 69 - 69

Опубликована: Янв. 4, 2025

Microplastics, defined as plastic fragments smaller than 5 mm, degrade from larger pollutants, with nanoscale microplastic particles presenting significant biological interactions. This study investigates the toxic effects of polystyrene nanoplastics (PS-NPs) on juvenile mice, which were exposed through lactation milk and drinking water at concentrations 0.01 mg/mL, 0.1 1 mg/mL. The results show that PS-NP exposure during periods caused delayed weight gain impaired organ development, particularly in liver kidneys, without causing functional abnormalities or injuries. primary toxicity PS-NPs was observed intestinal tract, including shortened villi, disrupted tight junctions, inhibited epithelial cell proliferation, oxidative stress responses. These findings highlight importance evaluating developmental environmentally relevant doses.

Язык: Английский

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Nanoplastics and microplastics released from an enzyme-embedded biodegradable polyester during hydrolysis

Journal of Hazardous Materials, Год журнала: 2025, Номер 489, С. 137640 - 137640

Опубликована: Фев. 16, 2025

Язык: Английский

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Micro-nanoplastics pollution and mammalian fertility: a systematic review and meta-analysis

Theriogenology, Год журнала: 2025, Номер 238, С. 117369 - 117369

Опубликована: Фев. 26, 2025

Язык: Английский

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