
Environment International, Год журнала: 2025, Номер 200, С. 109542 - 109542
Опубликована: Май 20, 2025
Язык: Английский
Environment International, Год журнала: 2025, Номер 200, С. 109542 - 109542
Опубликована: Май 20, 2025
Язык: Английский
Theoretical and Applied Climatology, Год журнала: 2025, Номер 156(1)
Опубликована: Янв. 1, 2025
Язык: Английский
Процитировано
1Environment International, Год журнала: 2025, Номер 196, С. 109269 - 109269
Опубликована: Янв. 10, 2025
The independent and interrelated long-term effects of the exposome such as air pollution, greenness, ambient temperature on lung function are not well understood, yet relevant in light climate change. Pre-bronchodilation FEV1 from five mature birth cohorts (N = 4724) three adult 6052) European countries were used to assess cross-sectional associations with temperature, assigned their residential address. All two-way interactions square terms a priori included building final elastic net regression model. Elastic results put into context different environmental scenarios improvement quality, change, or combinations. z-scores identified non-zero coefficients for many interaction terms, indicating importance joint exposure temperature. bigger more stable adults than children. Upon exploring benefits scenarios, an was expected scenario improving quality greenness. In contrast, negative changes characterized by daily increase summer decrease winter. beneficial pollution greenness attenuated presence Complex profiles showed adults, less extent children adolescents. Climate change seems have impact modifies association greenspace function.
Язык: Английский
Процитировано
1Urban Climate, Год журнала: 2024, Номер 58, С. 102161 - 102161
Опубликована: Окт. 12, 2024
Язык: Английский
Процитировано
5medRxiv (Cold Spring Harbor Laboratory), Год журнала: 2024, Номер unknown
Опубликована: Сен. 24, 2024
Abstract Large biobanks have set a new standard for research and innovation in human genomics implementation of personalised medicine. The Estonian Biobank was founded quarter century ago, its biological specimens, clinical, health, omics, lifestyle data been included over 800 publications to date. What makes the biobank unique internationally is translational focus, with active efforts conduct clinical studies based on genetic findings, explore effects return results participants. In this review we provide an overview Biobank, highlight strengths studying variation quantitative phenotypes health-related traits, development methods frameworks bringing into clinic, role as driving force implementing personalized medicine national level beyond.
Язык: Английский
Процитировано
4Environment International, Год журнала: 2025, Номер unknown, С. 109454 - 109454
Опубликована: Апрель 1, 2025
Язык: Английский
Процитировано
0Environment International, Год журнала: 2025, Номер 200, С. 109542 - 109542
Опубликована: Май 20, 2025
Язык: Английский
Процитировано
0