Ai-aided chronic mixture risk assessment along a small European river reveals multiple sites at risk and pharmaceuticals being the main risk drivers
Environment International,
Год журнала:
2025,
Номер
197, С. 109370 - 109370
Опубликована: Март 1, 2025
The
vast
amount
of
registered
chemicals
leads
to
a
high
diversity
substances
occurring
in
the
environment
and
creation
new
outpaces
chemical
risk
assessment
as
well
monitoring
strategies.
Hence,
strategies
need
be
modified
ensuring
that
they
remain
aligned
with
rapid
development
marketing
substances.
Here
we
performed
longitudinal
chronic
mixture
considering
real-world
case
study
scenario
diverse
anthropogenic
impact
types
characterised
by
different
land
uses
along
river
Central
Germany.
We
sampled
water
using
large-volume
solid
phase
extraction
at
six
selected
sampling
sites.
Following
analysis
liquid
chromatography-high
resolution
mass
spectrometry,
quantified
192
For
34
%
them,
obtained
empirical
effect
data
for
freshwater
organisms.
Furthermore,
used
open-source
artificial
intelligence
(AI)
model
TRIDENT
predict
toxicity
all
A
multi-scenario
was
conducted
three
taxonomic
groups,
concentration-addition
concept
various
hazard
exposure
scenarios.
results
showed
estimates
groups
were
considerably
higher
when
amended
from
silico
modelling.
identified
hotspots
pollution
our
indicated
fish
most
vulnerable
group,
pharmaceuticals
being
relevant
drivers.
Our
exemplifies
application
an
AI
aquatic
organisms
combination
consideration
multiple
scenarios
may
complement
future
Язык: Английский
Exposure to pesticides in Chile and its relationship with carcinogenic potential: a review
Frontiers in Public Health,
Год журнала:
2025,
Номер
13
Опубликована: Апрель 1, 2025
The
widespread
application
of
pesticides
in
agriculture
and
the
consequent
heightened
human
exposure
to
these
potentially
harmful
substances
present
considerable
environmental
health
risks.
potential
link
cancer
is
particularly
concerning,
underscoring
urgent
need
for
more
sustainable
health-conscious
agricultural
practices.
Pesticides
are
pervasive
global
contaminants,
with
occurring
through
various
routes.
Improper
use
associated
genotoxicity,
neurobehavioral
problems,
thyroid
dysfunction,
reproductive
issues,
cancer,
among
other
deleterious
damages.
While
pesticide
evident
Chile,
a
direct
remains
uncertain.
To
examine
scientific
evidence
on
environment
populations,
its
relationship
Chilean
territory.
search
original
articles
was
performed
international
peer-reviewed
databases,
including
Scopus,
Web
Science
(WoS),
PubMed
Advanced
Search
Builder.
Following
PRISMA
extension
review
guidelines,
included
studies
exposure,
biomarker
assessments,
experimental
investigations,
pesticide-cancer
associations
Chile.
Foreign
studies,
systematic
reviews,
meta-analyses
were
excluded.
Among
83
qualifying
conducted
between
1996
2024,
elevated
risks
documented,
71%
indicating
high
concentrations
that
may
pose
risk.
Additionally,
20%
reported
significant
chlorinated
compounds,
organochlorines
(OCs)
polychlorinated
biphenyls
(PCBs),
while
79.5%
identified
carcinogenic
humans
classified
by
International
Agency
Research
Cancer.
emphasizes
update
pesticide-related
regulations
implementing
bans
or
restrictions
establishing
stricter
standards
allowable
residue
levels
food.
Long-term
epidemiological
essential
concrete
links
specific
types
cancer.
investigating
epigenetic
markers
especially
occupational
settings,
critical.
Furthermore,
allocating
resources
prioritizing
further
research
fundamental,
regions
substantial
exposure.
Язык: Английский
Organic Micropollutants in Surface Water across China: Occurrence and Ecological Risk
Water Research,
Год журнала:
2025,
Номер
unknown, С. 123616 - 123616
Опубликована: Апрель 1, 2025
Язык: Английский
Assessing chemical pollution with biomonitoring approaches in streams and rivers: a critical review
Environmental Sciences Europe,
Год журнала:
2025,
Номер
37(1)
Опубликована: Май 8, 2025
Язык: Английский
Occurrence and environmental risk assessment of pesticides reveal important threats to aquatic organisms in precordilleran rivers of north-central Chile
The Science of The Total Environment,
Год журнала:
2025,
Номер
984, С. 179701 - 179701
Опубликована: Май 23, 2025
Язык: Английский
Multi-compartment impact of micropollutants and particularly antibiotics on bacterial communities using environmental DNA at river basin-level
Environmental Pollution,
Год журнала:
2024,
Номер
unknown, С. 125487 - 125487
Опубликована: Дек. 1, 2024
Bacterial
communities
respond
to
environmental
conditions
with
diverse
structural
and
functional
changes
depending
on
their
compartment
(water,
biofilm
or
sediment),
type
of
stress,
pollution
which
they
are
exposed.
In
this
study,
we
combined
amplicon
sequencing
bacterial
16S
rRNA
genes
from
water,
biofilm,
sediment
samples
collected
in
the
anthropogenically
impacted
River
Aconcagua
basin
(Central
Chile,
South
America),
order
evaluate
whether
micropollutants
alter
community
structure
functioning
based
degree
chemical
pollution.
Furthermore,
evaluated
potential
differently
polluted
sites
degrade
contaminants.
Our
results
show
a
lower
diversity
at
by
agriculture
urban
areas,
featuring
high
loads
micropollution
pesticides,
pharmaceuticals
personal
care
products
as
well
industrial
chemicals.
Nutrients,
antibiotic
micropollutant
explain
most
variability
community,
showing
significant
increase
groups
known
for
capabilities
various
organic
pollutants,
such
Nitrospira
also
selecting
taxa
resistance
Exiguobacterium
Planomicrobium.
Moreover,
ecological
functions
linked
biodegradation
toxic
chemicals
level
revealed
reductions
ecosystem-related
services
affected
wastewater
treatment
plant
(WWTP)
discharges
across
all
investigated
compartments.
Finally,
suggest
transitioning
simple
concentration-based
assessments
more
meaningful
pressure
values,
measured
concentrations
normalised
effect
information,
comprehensively
role
(biodiversity)
level.
Язык: Английский
Multi-compartment impact of micropollutants and particularly antibiotics on bacterial communities using environmental DNA at river basin-level
bioRxiv (Cold Spring Harbor Laboratory),
Год журнала:
2024,
Номер
unknown
Опубликована: Март 29, 2024
Abstract
Microbial
communities,
in
particular
bacterial
assemblies,
play
pivotal
roles
sustaining
biogeochemical
processes
within
ecosystems.
They
are
also
responsible
for
the
degradation
of
toxic
chemicals,
while
development
resistance
against
antimicrobial
drugs
jeopardises
human
health.
Bacterial
communities
respond
to
environmental
conditions
with
diverse
structural
and
functional
changes
depending
on
their
compartment
(water,
biofilm
or
sediment),
type
stress,
pollution
which
they
exposed.
In
this
study,
we
combined
amplicon
sequencing
16S
rRNA
genes
from
water,
biofilm,
sediment
samples
collected
anthropogenically
impacted
River
Aconcagua
basin
(Central
Chile,
South
America),
order
evaluate
whether
micropollutants
alter
community
structure
functioning
based
degree
chemical
pollution.
Furthermore,
evaluated
potential
differently
polluted
sites
degrade
contaminants.
Our
results
show
a
lower
diversity
at
by
agriculture
urban
areas,
featuring
high
loads
micropollution
pesticides,
pharmaceuticals
personal
care
products
as
well
industrial
chemicals.
Nutrients,
antibiotic
micropollutant
explain
most
variability
community,
showing
significant
increase
groups
known
capabilities
various
organic
pollutants,
such
Nistrospira
selecting
taxa
Exiguobacterium
Planomicrobium
.
Moreover,
ecological
functions
linked
biodegradation
chemicals
basing
level
revealed
reductions
ecosystem-related
services
affected
wastewater
treatment
plant
(WWTP)
discharges
across
all
investigated
compartments.
Finally,
suggest
transitioning
simple
concentration-based
assessments
more
meaningful
pressure
values
comprehensively
role
(biodiversity)
level.
Graphical
abstract
Highlights
Micropollutant
mixtures
altered
Antibiotic
stress
correlated
significantly
Reduction
related
contaminants
Water,
sediments
relevant
microbial
ecotoxicology
Язык: Английский
Multi-Compartment Impact of Micropollutants and Particularly Antibiotics on Bacterial Communities Using Environmental DNA at River Basin-Level
Опубликована: Янв. 1, 2024
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DOI
Язык: Английский
Prioritizing Binary Metal Organic Mixtures in European Freshwater: Who Drives the Risk?
Опубликована: Янв. 1, 2024
Язык: Английский
AI-aided chronic mixture risk assessment along a small European river reveals multiple sites at risk and pharmaceuticals being the main risk drivers
bioRxiv (Cold Spring Harbor Laboratory),
Год журнала:
2024,
Номер
unknown
Опубликована: Ноя. 18, 2024
Abstract
The
vast
amount
of
registered
chemicals
leads
to
a
high
diversity
substances
occurring
in
the
environment
and
creation
new
outpaces
chemical
risk
assessment
as
well
monitoring
strategies.
Hence,
strategies
need
be
modified
ensuring
that
they
remain
aligned
with
rapid
development
marketing
substances.
Here
we
performed
longitudinal
chronic
mixture
considering
real-world
case
study
scenario
diverse
anthropogenic
impact
types
characterised
by
different
land
uses
along
river
Central
Germany.
We
sampled
water
using
large-volume
solid
phase
extraction
at
six
selected
sampling
sites.
Following
analysis
liquid
chromatography-high
resolution
mass
spectrometry,
quantified
192
For
34%
them,
obtained
empirical
effect
data
for
freshwater
organisms.
Furthermore,
used
open-source
artificial
intelligence
(AI)
model
TRIDENT
predict
toxicity
all
A
multi-scenario
was
conducted
three
taxonomic
groups,
concentration-addition
concept
various
hazard
exposure
scenarios.
results
showed
estimates
groups
were
considerably
higher
when
amended
from
silico
modelling.
identified
hot
spots
pollution
our
indicated
fish
most
vulnerable
group,
pharmaceuticals
being
relevant
drivers.
Our
exemplifies
application
an
AI
aquatic
organisms
combination
consideration
multiple
scenarios,
may
complement
future
Highlights
organic
surface
samples
river.
Multiple
scenarios
considered
assessment.
Artificial
fill
gaps
ecotoxicity.
Fish
group
toxicity.
Pharmaceuticals
prevalent
Graphical
abstract
Язык: Английский