Lawsonia inermis (Henna) Extracts as a Sustainable Solution to Combat Multidrug-Resistant Gram-Negative Bacteria in Surface Water, Sewage, and Abattoir Leachate: A Quantitative Antimicrobial Analysis
Abstract
Antimicrobial
resistance
(AMR)
poses
a
critical
global
public
health
threat,
exacerbated
by
the
presence
of
multidrug-resistant
(MDR)
bacteria
in
environmental
matrices,
particularly
Low-
and
Middle-Income
Countries
(LMICs).
This
study
investigated
potential
Lawsonia
inermis
(Henna)
extracts
to
inhibit
MDR
surface
water,
sewage,
abattoir
leachate.
Using
cold
maceration
extraction
method,
methanol
aqueous
as
solvent,
antibacterial
activity
Henna
leaf
seed
was
assessed
against
eight
isolates
obtained
from
The
results
showed
exceptional
antimicrobial
activity,
especially
with
demonstrating
100%
inhibition
bacteria,
followed
(93.7%).
minimum
inhibitory
concentration
(MIC)
bactericidal
(MBC)
values
confirmed
efficacy
extracts.
All
displayed
profound
(AI)
S.
enterica
AGS2
strain.
Citrobacter
freundii
ADAI
most
susceptible
isolate.
Our
findings
suggest
that
could
serve
viable,
eco-friendly,
cost-effective
solution
for
reducing
LMICs.
highlights
plant-based
products
combating
AMR
matrices
promoting
health.
have
significant
implications
development
sustainable
leachate
water
treatment
strategies
control
LMICs
through
solutions.
Research Square (Research Square), Год журнала: 2024, Номер unknown
Опубликована: Окт. 16, 2024
Язык: Английский