The porcine corpus luteum as a model for studying the effects of nanoplastics DOI Creative Commons
Giuseppina Basini, Simone Bertini,

Simona Bussolati

и другие.

Environmental Toxicology and Pharmacology, Год журнала: 2024, Номер 110, С. 104503 - 104503

Опубликована: Июль 24, 2024

Nanoplastics (NPs) affect fertility. We evaluated the effects of NPs treatment on luteal and endothelial cells. examined crucial markers growth redox status. did not induce changes in ATP levels cells, while it increased (p< 0.05) their proliferation. In no change proliferation was detected, an increase (p<0.05) observed. The reactive oxygen species, superoxide anion nitric oxide (p<0.001) detected both cell types, which also showed dismutase enzyme activity as well non-enzymatic antioxidant power (p<0.05). A decrease progesterone production vascular factor were addition, a dose-dependent accumulation cells shown, that likely occurred through adhesion internalization. Results underline potential risk for corpus luteum functionality.

Язык: Английский

The porcine corpus luteum as a model for studying the effects of nanoplastics DOI Creative Commons
Giuseppina Basini, Simone Bertini,

Simona Bussolati

и другие.

Environmental Toxicology and Pharmacology, Год журнала: 2024, Номер 110, С. 104503 - 104503

Опубликована: Июль 24, 2024

Nanoplastics (NPs) affect fertility. We evaluated the effects of NPs treatment on luteal and endothelial cells. examined crucial markers growth redox status. did not induce changes in ATP levels cells, while it increased (p< 0.05) their proliferation. In no change proliferation was detected, an increase (p<0.05) observed. The reactive oxygen species, superoxide anion nitric oxide (p<0.001) detected both cell types, which also showed dismutase enzyme activity as well non-enzymatic antioxidant power (p<0.05). A decrease progesterone production vascular factor were addition, a dose-dependent accumulation cells shown, that likely occurred through adhesion internalization. Results underline potential risk for corpus luteum functionality.

Язык: Английский

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