A review on the combined toxicological effects of microplastics and their attached pollutants

Emerging contaminants, Год журнала: 2025, Номер unknown, С. 100486 - 100486

Опубликована: Фев. 1, 2025

Язык: Английский

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Reproductive and developmental implications of micro- and nanoplastic internalization: Recent advances and perspectives

Ecotoxicology and Environmental Safety, Год журнала: 2024, Номер 286, С. 117245 - 117245

Опубликована: Окт. 25, 2024

Язык: Английский

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Dose-dependent toxic effects of triclosan on Rana omeimontis larvae: insights into potential implications for neurodegenerative diseases

Journal of Hazardous Materials, Год журнала: 2025, Номер 487, С. 137187 - 137187

Опубликована: Янв. 10, 2025

Язык: Английский

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Co-Existing Nanoplastics Further Exacerbates the Effects of Triclosan on the Physiological Functions of Human Serum Albumin

Life, Год журнала: 2025, Номер 15(1), С. 112 - 112

Опубликована: Янв. 16, 2025

The potential health risks posed by the coexistence of nanoplastics (NPs) and triclosan (TCS) have garnered significant attention. However, effects underlying mechanisms NPs TCS on key functional proteins at molecular level remain poorly understood. This study reports effect polystyrene (PSNPs) binding to human serum albumin (HSA) using multispectral methods simulation systems. experimental results show that significantly inhibits HSA esterase activity, with exacerbating inhibition in presence PSNPs, which is attributed alteration conformation microenvironment amino acid residues induced PSNPs. Molecular docking site marker competitive studies indicate predominantly binds I subdomain Sudlow II PSNPs does not affect sites. Spectra analyses quenching mechanism between belongs static type change fluorescence type. conformational alterations are further enhanced indicating enhance making more accessible provides valuable information about toxicity case co-exposure.

Язык: Английский

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Sex-specific reproductive toxicity of subacute exposure to glufosinate-ammonium in zebrafish (Danio rerio)

The Science of The Total Environment, Год журнала: 2025, Номер 963, С. 178489 - 178489

Опубликована: Янв. 17, 2025

Язык: Английский

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Reproductive toxicity and parental transmission effects of 4-methylbenzylidene camphor (4-MBC) exposure in adult zebrafish

Aquatic Toxicology, Год журнала: 2025, Номер unknown, С. 107334 - 107334

Опубликована: Март 1, 2025

Язык: Английский

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Effect of polystyrene nanoplastics on the intestinal histopathology, oxidative stress, and microbiota of Acrossocheilus yunnanensis

Aquatic Toxicology, Год журнала: 2025, Номер unknown, С. 107359 - 107359

Опубликована: Апрель 1, 2025

Язык: Английский

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Long-term exposure to environmentally relevant concentrations of tri-m-cresyl phosphate induces fecundity decline and gonadal dysplasia by disrupting reproductive endocrine homeostasis

Environmental Pollution, Год журнала: 2025, Номер 374, С. 126280 - 126280

Опубликована: Апрель 19, 2025

Язык: Английский

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The potential of microplastics acting as vector for triclosan in aquatic environments

Aquatic Toxicology, Год журнала: 2025, Номер 284, С. 107381 - 107381

Опубликована: Апрель 23, 2025

Язык: Английский

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Plastic Fly: What Drosophila melanogaster Can Tell Us about the Biological Effects and the Carcinogenic Potential of Nanopolystyrene

International Journal of Molecular Sciences, Год журнала: 2024, Номер 25(14), С. 7965 - 7965

Опубликована: Июль 21, 2024

Today, plastic pollution is one of the biggest threats to environment and public health. In tissues exposed species, micro- nano-fragments accumulate, leading genotoxicity, altered metabolism, decreased lifespan. A model investigate genotoxic tumor-promoting potential nanoplastics (NPs) Drosophila melanogaster. Here we tested polystyrene, which commonly used in food packaging, not well recycled, makes up at least 30% landfills. order biological effects carcinogenic 100 µm polystyrene nanoparticles (PSNPs), raised Oregon [R] wild-type flies on contaminated food. After prolonged exposure, fluorescent PSNPs accumulated gut fat bodies. Furthermore, PSNP-fed showed considerable alterations weight, developmental time, lifespan, as a compromised ability recover from starvation. Additionally, noticed decrease motor activity DNAlig4 mutants fed with PSNPs, are known be susceptible dietary stressors. qPCR molecular investigation larval intestines revealed markedly elevated expression genes drice p53, suggesting response cell damage. Lastly, warts-defective assess discovered that had more aberrant masses than untreated ones. summary, our findings support notion ingested nanopolystyrene triggers metabolic genetic modifications organisms, eventually delaying development accelerating death disease.

Язык: Английский

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