Meta-Analysis of the Impact of Low-Dose Ionizing Radiation on Mortality and Progression of Heart Disease in the General Patient Population: Insights from Hormesis Theory in Cardiology DOI Open Access
Mateusz Pocięgiel,

Piotr Opyd,

Tomasz Zawodny

и другие.

Journal of Clinical Medicine, Год журнала: 2024, Номер 13(22), С. 6909 - 6909

Опубликована: Ноя. 16, 2024

Low-dose ionizing radiation (LDIR) is commonly used in medical diagnoses and certain professions, but its long-term effects on noncancer diseases, particularly cardiovascular disease (CVD), remain uncertain. While LDIR has recognized diagnostic benefits, influence CVD mortality progression still debated, with some suggesting that low doses may even have beneficial effects, as per the hormesis theory.

Язык: Английский

High-Fat Diet and Altered Radiation Response DOI Creative Commons
Jiraporn Kantapan, Takanori Katsube, Bing Wang

и другие.

Biology, Год журнала: 2025, Номер 14(4), С. 324 - 324

Опубликована: Март 22, 2025

High-fat diets (HFDs) have become increasingly prevalent in modern societies, driving rising rates of obesity and metabolic syndrome. Concurrently, radiation exposure from medical treatments environmental sources poses health risks shaped by both biological factors. This review explores the intersection between HFDs sensitivity/susceptibility, focusing on how diet-induced alterations influence body’s response to radiation. Evidence preclinical clinical studies indicates that significantly alter metabolism, leading increased oxidative stress immune system dysregulation. These changes can exacerbate radiation-induced stress, inflammation, DNA damage, potentially increasing sensitivity normal tissues. Conversely, HFD-induced disruptions may activate cellular pathways involved repair, cell survival, inflammatory responses, fostering tumor resistance modifying microenvironment, which impair efficacy therapy cancer treatment. Understanding interplay diet is critical for optimizing public guidelines improving therapeutic outcomes. findings underscore need further research into dietary interventions mitigate radiation-associated risks.

Язык: Английский

Процитировано

0

Meta-Analysis of the Impact of Low-Dose Ionizing Radiation on Mortality and Progression of Heart Disease in the General Patient Population: Insights from Hormesis Theory in Cardiology DOI Open Access
Mateusz Pocięgiel,

Piotr Opyd,

Tomasz Zawodny

и другие.

Journal of Clinical Medicine, Год журнала: 2024, Номер 13(22), С. 6909 - 6909

Опубликована: Ноя. 16, 2024

Low-dose ionizing radiation (LDIR) is commonly used in medical diagnoses and certain professions, but its long-term effects on noncancer diseases, particularly cardiovascular disease (CVD), remain uncertain. While LDIR has recognized diagnostic benefits, influence CVD mortality progression still debated, with some suggesting that low doses may even have beneficial effects, as per the hormesis theory.

Язык: Английский

Процитировано

0