Comparative growth inhibition of 6PPD and 6PPD-Q on microalgae Selenastrum capricornutum, with insights into 6PPD-induced phototoxicity and oxidative stress DOI
Xiaopeng Yan, Claude Kiki,

Zijie Xu

и другие.

The Science of The Total Environment, Год журнала: 2024, Номер 957, С. 177627 - 177627

Опубликована: Дек. 1, 2024

Язык: Английский

Mass Spectrometry Imaging Unveils the Metabolic Effect of 6PPD-Quinone in Exposed Mice DOI
Ke Jia,

Jiameng Sun,

Qiuyao Du

и другие.

Environmental Science & Technology, Год журнала: 2025, Номер unknown

Опубликована: Фев. 25, 2025

N-(1,3-dimethylbutyl)-N′-phenyl-p-phenylenediamine quinone (6PPD-Q) has gained widespread attention as an emerging significant environmental contaminant, but its biochemical toxicity in mammals remains inadequately explored. In this study, the systemic toxicological effects of 6PPD-Q mouse models exposed to both high and low doses were investigated. Matrix-assisted laser desorption/ionization mass spectrometry imaging (MALDI MSI) was applied evaluate on major organs, including liver, kidneys, spleen, testes. Notably, caused similar multiorgan metabolic disturbances, with changes antioxidant levels, highlighting oxidative stress a key factor 6PPD-Q-induced damage. Further results revealed that disrupts critical pathways, glutathione metabolism, ascorbic acid energy amino which are associated stress, immune dysfunction, disruptions kidney testis. This study provides important insights into mechanisms underscores need for further research assess potential health risks, could guide future policies human risk assessments.

Язык: Английский

Процитировано

1
6-PPD triggered lipid metabolism disorder and inflammatory response in larval zebrafish (Danio rerio) by regulating PPARγ/NF-κB pathway DOI
Qiuhui Qian,

Ji Wu,

Cuizhen Wang

и другие.

Environmental Pollution, Год журнала: 2025, Номер unknown, С. 125785 - 125785

Опубликована: Фев. 1, 2025

Язык: Английский

Процитировано

0
Exploring the Fate of 6PPD in Zebrafish (Danio rerio): Understanding Toxicokinetics, Biotransformation Mechanisms, and Metabolomic Profiling at Environmentally Relevant Levels DOI
Chenyang Rao,

Yanxia Zuo,

Dongfang Xiang

и другие.

Journal of Hazardous Materials, Год журнала: 2025, Номер 489, С. 137687 - 137687

Опубликована: Фев. 20, 2025

Язык: Английский

Процитировано

0
Associations of Human Exposure to 6PPD and 6PPDQ with Colorectal Cancer: A Mixture Analysis DOI

Yangbo Lv,

Weili Mao, Hangbiao Jin

и другие.

Environmental Pollution, Год журнала: 2025, Номер unknown, С. 126114 - 126114

Опубликована: Март 1, 2025

Язык: Английский

Процитировано

0
6PPD-quinone Exposure Induces Oxidative Damage and Physiological Disruption in Eisenia fetida: An Integrated Analysis of Phenotypes, Multi-omics, and Intestinal Microbiota DOI
Hanghai Zhou, Zhou Wu, Xin Wei Wang

и другие.

Journal of Hazardous Materials, Год журнала: 2025, Номер unknown, С. 138334 - 138334

Опубликована: Апрель 1, 2025

Язык: Английский

Процитировано

0
Response of Ceratophyllum demersum L. and its epiphytic biofilms to 6PPD and 6PPD-Q exposure: Based on metabolomics and microbial community analysis DOI
Xiang Li, Weitao Liu,

Yichen Ge

и другие.

Journal of Hazardous Materials, Год журнала: 2024, Номер 480, С. 136420 - 136420

Опубликована: Ноя. 5, 2024

Язык: Английский

Процитировано

1
Comparative growth inhibition of 6PPD and 6PPD-Q on microalgae Selenastrum capricornutum, with insights into 6PPD-induced phototoxicity and oxidative stress DOI
Xiaopeng Yan, Claude Kiki,

Zijie Xu

и другие.

The Science of The Total Environment, Год журнала: 2024, Номер 957, С. 177627 - 177627

Опубликована: Дек. 1, 2024

Язык: Английский

Процитировано

1