Polystyrene nanoplastics amplify the toxic effects of PFOA on the Chinese mitten crab (Eriocheir sinensis)
Journal of Hazardous Materials,
Год журнала:
2025,
Номер
488, С. 137488 - 137488
Опубликована: Фев. 4, 2025
Язык: Английский
Long-chain perfluoroalkylether carboxylic acids PFO5DoA and PFO4DA alter glucose, bile acid, and thyroid hormone homeostasis in fetal rats from 5-day maternal oral exposure
Environmental Research,
Год журнала:
2024,
Номер
unknown, С. 120210 - 120210
Опубликована: Окт. 1, 2024
Язык: Английский
Emerging per- and polyfluoroalkyl substance perfluoro-(3,5,7,9-tetraoxadecanoic) acid (PFO4DA) impairs steroidogenesis and spermatogenesis by suppressing StAR and CYP11A1 expression in mice
Ecotoxicology and Environmental Safety,
Год журнала:
2025,
Номер
292, С. 117962 - 117962
Опубликована: Фев. 26, 2025
Язык: Английский
Synthesis and Characterization of a Series of Biofriendly Fluoroether Betaines
Langmuir,
Год журнала:
2025,
Номер
unknown
Опубликована: Март 27, 2025
Fluoroether
approach
has
been
extensively
employed
as
an
alternative
to
conventional
fluorinated
surfactants;
however,
it
faces
challenges
such
inadequate
performance
of
short
fluoroether
chains
and
environmental
contamination
from
long
chains.
This
study
aims
address
the
conflict
between
compatibility
surfactants.
The
design
surfactants
is
centered
around
OC
chain
(CF3(OCF2)n–),
utilizing
reduced
fluorine
content
achieve
superior
surface
activity.
A
series
surfactant
molecules
featuring
elongated
hydrophobic
dual-chain
structures
have
synthesized
characterized.
All
good
activity
at
low
concentrations.
Among
them,
CF3(OCF2)4CH2O(CH2)3SO2NH(CH2)3N+(CH3)2CH2COO–
(OC4F-B),
which
employs
a
strategy
extending
by
insertion
–CH2O(CH2)3–,
shows
best
performance.
can
tension
20
mN/m
concentration
0.005
wt
%,
times
lower
than
that
required
for
CF3(OCF2)4CONH(CH2)3N+(CH3)2CH2COO–
(OC4-betaine)
attain
same
tension.
In
contrast,
(CF3(OCF2)3CH2O(CH2)3SO2NHCH2CH2)2N+(CH3)CH2COO–
(DOC3F-B),
both
extended
carbon
strategies,
exhibits
critical
micelle
diminished
2
orders
magnitude
relative
OC3-betaine,
reaching
0.047
g/L.
Merely
adjusting
length
fluorocarbon
insufficient
reconcile
impact
introduces
innovative
incorporating
hydrocarbon
adopting
design,
thereby
addressing
this
challenge
effectively.
Язык: Английский
Per- and Polyfluoroalkyl Ether Acid (PFEA) Concentrations in Indoor Dust are Higher in Homes Closer to a Fluorochemical Manufacturing Facility
Environmental Science & Technology,
Год журнала:
2025,
Номер
unknown
Опубликована: Март 31, 2025
Concentrations
of
48
per-
and
polyfluoroalkyl
substances
(PFAS)
were
measured
in
settled
dust
samples
from
65
homes
GenX
Exposure
Study
participants
residing
near
a
fluorochemical
manufacturing
facility
North
Carolina.
Eight
PFAS
[perfluoro(3,5-dioxahexanoic)
acid
(aka
PFO2HxA),
perfluoro-2-(perfluoromethoxy)propanoic
(PMPA),
perfluoro-2-ethoxypropanoic
(PEPA),
6:2
fluorotelomer
phosphate
diester
(6:2
diPAP),
6:2/8:2
(6:2/8:2
perfluoropropanoic
(PFPrA),
perfluorodecanesulfonic
(PFDS),
2-(N-ethyl-perfluorooctanesulfonamido)acetic
(N-EtFOSAA)]
detected
>90%
the
samples.
Dust
concentrations
six
ether
acids
(PFEAs)
produced
at
(PEPA,
PMPA,
perfluoro-2-methoxyacetic
(PFMOAA),
PFO2HxA,
hexafluoropropylene
oxide
dimer
(HFPO-DA
aka
GenX),
ethanesulfonic
acid,
2-[1-[difluoro(1,2,2,2-tetrafluoroethoxy)methyl]-1,2,2,2-
tetrafluoroethoxy]-1,1,2,2-tetrafluoro-
(Nafion
byproduct
2)
significantly
negatively
associated
with
home
distance
facility.
Homes
closer
to
had
higher
summed
mass
12
targeted
PFEAs
(∑12PFEAs)
but
not
∑48PFAS.
Trifluoroacetic
(TFA),
an
ultrashort
chain
PFAS,
three
diPAPs
(8:2/6:2
diPAP,
8:2
diPAP)
major
contributors
∑48PFAS,
these
compounds
did
show
relationships
distance.
Based
on
our
previous
findings
associating
well
water
human
serum,
current
indicate
could
be
important
exposure
source.
Язык: Английский
Associations of Serum Per- and Polyfluoroalkyl Substances with Genotoxic Biomarkers: New Insights from Cross-Sectional and In Vivo Evidence
Environmental Science & Technology,
Год журнала:
2025,
Номер
unknown
Опубликована: Апрель 25, 2025
The
effects
of
perfluoroalkyl
and
polyfluoroalkyl
substances
(PFAS)
on
genomic
stability
remain
unclear.
Here,
a
cross-sectional
study
was
conducted
to
establish
the
associations
PFAS
with
genotoxic
biomarkers.
We
recruited
cohort
453
residents
in
2021
Zhejiang,
China.
Thirty
serum
were
quantified,
alongside
seven
indicators
[five
rDNA
copy
numbers
(rDNA-CN),
mitochondrial
DNA
(mtDNA-CN),
relative
telomere
length
(RTL)]
whole
blood.
Results
showed
that
PFUnDA,
perfluorohexanesulfonic
acid
(PFHxS),
perfluorooctanesulfonic
(PFOS),
6:2
Cl-PFESA,
PFO5DoDA
positively
correlated
rDNA-CN,
while
PFHpA,
PFOA,
PFMOAA
inverse
associations.
PFO4DA
mtDNA-CN.
HFPO-TA,
negatively
associated
RTL,
perfluorononanoic
acid,
PFHxS,
PFOS,
Cl-PFESA
positive
Nonlinear
exposure-response
relationships
also
observed
between
biomarkers
using
restricted
cubic
spline
models.
Furthermore,
mixtures
mtDNA-CN,
showing
highest
contribution
by
quantile-based
g-computation
model.
In
vivo
studies
further
confirmed
increased
mtDNA-CN
male
mice
dose-dependent
manner.
This
provides
novel
evidence
disrupt
stability,
varying
functional
groups
fluoroalkyl(ether)
chain
lengths.
Язык: Английский