Life, Год журнала: 2025, Номер 15(4), С. 547 - 547

Опубликована: Март 26, 2025

The widespread application of herbicides has profound ecological consequences, particularly regarding the distribution antibiotic resistance genes (ARGs) and microbial communities. In this study, we analyzed herbicide-related metagenomic data to assess impact herbicide exposure on ARGs populations. Our results demonstrate that significantly increased abundance ARGs, those associated with multidrug resistance, sulfonamides, bacitracin, notable increases in subtypes such as bacA sul1. Microbial community analyses revealed a dominance Pseudomonadota Actinomycetota, along significant down-regulation genera like Fibrisoma, Gilsonvirus, Limnobacter, Wilnyevirus experimental group. Additionally, led marked reduction biodiversity. When threshold values were relaxed, correlation co-occurrence pattern between multiple sul1, suggesting horizontal gene transfer plays pivotal role spread herbicide-contaminated soils. Moreover, environmental factors found influence both composition ARG distribution. These findings highlight complex effects diversity dissemination genes, emphasizing need for further research into long-term public health implications use.

Язык: Английский