Опубликована: Авг. 7, 2024

The COVID-19 pandemic has revealed significant disparities in disease severity and mortality across various population groups regions. These cannot be attributed solely to healthcare systems, socioeconomic factors, living conditions, or individual immune landscapes; environmental factors also play a crucial role. This work explores how variations nasal morphology related age, gender, race can affect the respiratory system's ability filter, warm, humidify inhaled air. may contribute differences cold, dry, polluted, infected air impact system, thus influencing observed patterns of outcomes. analysis suggests that individuals with genetically determined wider cavities, often found populations originating from warmer climates, have decreased filtration conditioning efficiency, leading increased susceptibility infections disproportionately high rates COVID-19. Moreover, age-related changes morphology, such as volume involution atrophy mucosa, impaired filtration, thereby increasing risk severe outcomes elderly. Gender men typically having larger passages compared women, are linked poorer potentially contributing higher men. Preliminary statistical analyses U.S. suggest favorable structures longer life expectancy than those less optimal anatomy; however, this should regarded hypothesis. findings underscore gaps our understanding highlight urgent need for further research unravel complex interplay between system dynamics, shaping

Язык: Английский