Pharmaceutics,
Год журнала:
2023,
Номер
15(5), С. 1514 - 1514
Опубликована: Май 17, 2023
At
present,
colorectal
cancer
(CRC)
is
the
second
deadliest
type
of
cancer,
partly
because
a
high
percentage
cases
are
diagnosed
at
advanced
stages
when
tumors
have
already
metastasized.
Thus,
there
an
urgent
need
to
develop
novel
diagnostic
systems
that
allow
early
detection
as
well
new
therapeutic
more
specific
than
those
currently
available.
In
this
context,
nanotechnology
plays
very
important
role
in
development
targeted
platforms.
recent
decades,
many
types
nanomaterials
with
advantageous
properties
been
used
for
nano-oncology
applications
and
loaded
different
agents,
capable
recognizing
tumor
cells
or
biomarkers.
Indeed,
among
most
widely
monoclonal
antibodies,
administration
them
approved
by
main
drug
regulatory
agencies
treatment
several
including
CRC.
way,
review
comprehensively
discusses
drawbacks
conventional
screening
technologies
CRC,
it
presents
advances
application
antibody-loaded
nanoplatforms
CRC
detection,
therapy
theranostics
applications.
Therapeutic Delivery,
Год журнала:
2024,
Номер
15(10), С. 781 - 799
Опубликована: Сен. 24, 2024
Superficial
cancers
typically
refer
to
confined
the
surface
layers
of
tissue.
Low-targeting
therapies
or
side
effects
prompt
exploration
novel
therapeutic
approaches.
Gold
nanoparticles
(AuNPs),
due
their
unique
optical
properties,
serve
as
effective
photosensitizers,
enabling
tumor
ablation
through
photothermal
therapy
(PTT).
PTT
induced
by
AuNPs
can
be
achieved
light
sources
externally
applied
skin.
Near-infrared
radiation
is
main
candidate
its
deep
tissue
penetration
capability.
This
review
explores
recent
advancements
in
AuNP-based
for
superficial
cancers,
specifically
breast,
head
and
neck,
thyroid,
bladder
prostate
cancers.
Additionally,
challenges
future
directions
utilizing
cancer
treatment
are
discussed,
emphasizing
importance
balancing
efficacy
with
safety
clinical
applications.
Nanotheranostics,
Год журнала:
2024,
Номер
8(4), С. 535 - 560
Опубликована: Сен. 30, 2024
Excessive
stomach
acid
or
bacterial
infection
are
the
root
causes
of
gastric
acid-related
disorders,
such
as
peptic
ulcer
disease
and
gastroesophageal
reflux
disease.
Proton
pump
inhibitors
including
lansoprazole,
omeprazole,
esomeprazole,
rabeprazole,
etc.
medications
used
to
treat
diseases.
One
most
effective
drugs
for
treating
is
vonoprazan,
owing
its
ability
strongly
inhibit
acid.
vonoprazan
work
in
distinct
ways
prevent
production
Vonoprazan
inhibits
secretion
by
blocking
potassium-competitive
blocker
receptor,
whereas
proton
function
irreversibly
parietal
cells
stomach.
Delayed
release
tablets,
delayed
capsules,
minitablets,
pellets,
bilayer,
floating,
mucoadhesive
tablets
nanoparticles,
some
methods
development
micro/nano
formulations
with
vonoprazan.
Diagnosis
therapy
illnesses,
particularly
those
treated
inhibitors,
rely
heavily
on
imaging
modalities
CT
scans,
X-rays,
endoscopy,
fluorescence
HRM
imaging.
This
review
provides
a
comprehensive
update
various
micro/nanoformulations
Moreover,
we
provide
an
outlook
clinical
formulation
related
We
have
limited
our
discussion
case
studies
trials
Journal of Biomedical Materials Research Part B Applied Biomaterials,
Год журнала:
2022,
Номер
111(4), С. 795 - 804
Опубликована: Ноя. 16, 2022
Recent
studies
have
highlighted
the
development
prospects
of
magnetic
hyperthermia
in
cancer
therapy.
A
few
on
application
Fe3
O4
nanospheres
for
gynecological
malignancies
achieved
certain
efficacy,
but
there
was
no
visible
progress
currently.
In
this
work,
modified
with
polyetherimide
(PEI)
and
folic
acid
(FA)
were
synthesized
using
a
hydrothermal
method
possible
utility
biocompatible
active
tumor-targeting
induction
hyperthermia.
The
PEI-
FA-coated
showed
high
crystallinity,
well-dispersed
spherical
structures
ideal
Ms
value.
As
result,
designed
@
PEI@FA
higher
specific
absorption
rate
(SAR)
values
at
360
kHz
308
Oe,
as
well
excellent
biocompatibility
Hela,
SKOV3,
HEC-1-A
NIH3T3
cells.
These
can
be
used
an
optimal
heating
agent
treatment
cancers.
Pharmaceutics,
Год журнала:
2023,
Номер
15(5), С. 1514 - 1514
Опубликована: Май 17, 2023
At
present,
colorectal
cancer
(CRC)
is
the
second
deadliest
type
of
cancer,
partly
because
a
high
percentage
cases
are
diagnosed
at
advanced
stages
when
tumors
have
already
metastasized.
Thus,
there
an
urgent
need
to
develop
novel
diagnostic
systems
that
allow
early
detection
as
well
new
therapeutic
more
specific
than
those
currently
available.
In
this
context,
nanotechnology
plays
very
important
role
in
development
targeted
platforms.
recent
decades,
many
types
nanomaterials
with
advantageous
properties
been
used
for
nano-oncology
applications
and
loaded
different
agents,
capable
recognizing
tumor
cells
or
biomarkers.
Indeed,
among
most
widely
monoclonal
antibodies,
administration
them
approved
by
main
drug
regulatory
agencies
treatment
several
including
CRC.
way,
review
comprehensively
discusses
drawbacks
conventional
screening
technologies
CRC,
it
presents
advances
application
antibody-loaded
nanoplatforms
CRC
detection,
therapy
theranostics
applications.
