Journal of Clinical Medicine,
Год журнала:
2024,
Номер
13(9), С. 2668 - 2668
Опубликована: Май 2, 2024
Preeclampsia
(PE)
is
a
hypertensive
disorder
in
pregnancy
associated
with
significant
fetal
and
maternal
complications.
Antiphospholipid
syndrome
(APS)
an
acquired
form
of
thrombophilia
characterized
by
recurrent
venous
or
arterial
thrombosis
obstetric
complications
that
significantly
increases
morbidity
mortality
rates.
While
preeclampsia
may
not
be
the
most
prevalent
complication
APS,
it
impacts
long-term
health
both
mother
child.
The
treatment
antiphospholipid
different
from
as
independent
disease.
Despite
current
treatments
involving
anticoagulants,
antiplatelet
agents,
antihypertensive
drugs,
persist,
underscoring
need
for
cohesive
management
effective
treatments.
objective
our
review
to
briefly
present
knowledge
about
physiopathology
role
antibodies
this
process.
Based
on
existing
literature,
aims
identify
future
directions
molecular
pathology
toward
discovery
biomarkers
targeted
application
multidisciplinary
approaches
prognostic
models,
including
new
biomarkers,
could
beneficial
prediction
PE.
International Journal of Molecular Sciences,
Год журнала:
2024,
Номер
25(3), С. 1687 - 1687
Опубликована: Янв. 30, 2024
In
an
increasingly
aging
society,
there
is
a
growing
demand
for
the
development
of
technology
related
to
tissue
regeneration.
It
involves
appropriate
biomaterials
whose
properties
will
allow
desired
biological
response
be
obtained.
Bioactivity
strongly
affected
by
proper
selection
active
ingredients.
The
aim
this
study
was
produce
bioactive
hydrogel
materials
based
on
hyaluronic
acid
and
collagen
modified
addition
placenta.
These
were
intended
use
as
dressings,
their
physicochemical
investigated
under
simulated
environmental
conditions.
incubated
in
vitro
different
fluids
simulating
environment
human
body
(e.g.,
fluid)
then
stored
at
temperature
close
temperature.
Using
FT-IR
spectrophotometer,
functional
groups
present
composites
identified.
with
added
placenta
showed
increase
swelling
factor
more
than
300%.
results
obtained
confirmed
potential
using
material
absorbent
dressing.
This
indicated
pH
conductometric
measurements,
sorption,
degradation,
surface
analysis
optical
microscope.
evaluation
cytosafety
tested
biomaterials.
activate
monocytes,
which
may
indicate
beneficial
first
phases
wound
healing.
proved
nontoxic
has
medical
use.
Diseases,
Год журнала:
2024,
Номер
12(3), С. 59 - 59
Опубликована: Март 20, 2024
In
mammals,
the
placenta
is
a
connection
between
mother
and
new
developing
organism.
This
tissue
has
protective
function
against
some
microorganisms,
transports
nutrients,
exchanges
gases
excretory
substances
fetus.
Placental
mainly
composed
of
chorionic
villi
functional
units
called
trophoblasts
(cytotrophoblasts,
syncytiotrophoblast,
extravillous
trophoblasts).
However,
viruses
have
developed
mechanisms
that
help
them
invade
placenta,
causing
various
conditions
such
as
necrosis,
poor
perfusion,
membrane
rupture
which,
in
turn,
can
impact
development
fetus
put
mother’s
health
at
risk.
this
study,
we
collected
most
relevant
information
about
viral
infection
during
pregnancy
which
affect
both
fetus,
leading
to
an
increase
probability
vertical
transmission.
Knowing
these
could
be
for
research
maternal–fetal
context
may
provide
options
therapeutic
targets
biomarkers
fetal
prognosis.
Journal of Personalized Medicine,
Год журнала:
2024,
Номер
14(7), С. 698 - 698
Опубликована: Июнь 28, 2024
Fetal
growth
restriction
(FGR),
or
intrauterine
(IUGR),
is
still
the
second
most
common
cause
of
perinatal
mortality.
The
factors
that
contribute
to
fetal
can
be
categorized
into
three
distinct
groups:
placental,
fetal,
and
maternal.
prenatal
application
various
diagnostic
methods
can,
in
many
cases,
detect
deterioration
condition
time
because
nature
above
disorder
thoroughly
investigated
by
applying
a
combination
biophysical
biochemical
methods,
which
determine
state
embryo-placenta
unit
assess
possible
increased
risk
failure
outcome
potential
for
later
health
problems.
When
considering
therapeutic
intervention,
key
question
whether
it
utilized
during
pregnancy.
Currently,
there
are
no
known
treatment
interventions
effectively
enhance
placental
function
promote
weight
development.
Nevertheless,
cases
with
fetuses
diagnosed
restriction,
immediate
termination
pregnancy
may
have
advantages
not
only
terms
minimizing
mortality
but
primarily
reducing
long-term
morbidity
childhood
maturity.
Journal of Clinical Medicine,
Год журнала:
2024,
Номер
13(9), С. 2668 - 2668
Опубликована: Май 2, 2024
Preeclampsia
(PE)
is
a
hypertensive
disorder
in
pregnancy
associated
with
significant
fetal
and
maternal
complications.
Antiphospholipid
syndrome
(APS)
an
acquired
form
of
thrombophilia
characterized
by
recurrent
venous
or
arterial
thrombosis
obstetric
complications
that
significantly
increases
morbidity
mortality
rates.
While
preeclampsia
may
not
be
the
most
prevalent
complication
APS,
it
impacts
long-term
health
both
mother
child.
The
treatment
antiphospholipid
different
from
as
independent
disease.
Despite
current
treatments
involving
anticoagulants,
antiplatelet
agents,
antihypertensive
drugs,
persist,
underscoring
need
for
cohesive
management
effective
treatments.
objective
our
review
to
briefly
present
knowledge
about
physiopathology
role
antibodies
this
process.
Based
on
existing
literature,
aims
identify
future
directions
molecular
pathology
toward
discovery
biomarkers
targeted
application
multidisciplinary
approaches
prognostic
models,
including
new
biomarkers,
could
beneficial
prediction
PE.
