Vertical transmission of SARS-CoV-2 – data from the German COVID-19 related obstetric and neonatal outcome study (CRONOS)

Journal of Perinatal Medicine, Год журнала: 2024, Номер 52(2), С. 202 - 209

Опубликована: Янв. 4, 2024

Abstract Objectives We aimed to determine the frequency of SARS-CoV-2 positivity in newborns born mothers with peripartum infection a German cohort, identify potential risk factors associated neonatal infection, and present short-term outcomes vertical transmission SARS-CoV-2. Methods Data on women occurring anytime during their pregnancy was gathered prospectively within CRONOS registry. From April 2020 February 2023 total 8,540 had been registered. The timing probability mother-to-child neonates perinatal were classified using WHO classification system. severity maternal vaccination status, type dominant virus, outcome parameters analyzed as for infection. Results 6.3 % resp. 42.9 tested stillbirths positive. 2.1 confirmed possible identified. Severe COVID-19 (odds ratio 4.4, 95 confidence interval 1.8–11.1) Delta virus (OR 3.2, 1.4–7.7) Newborns or significantly more often admitted NICU (65.2 vs. 27.5 non, p<0.001). Conclusions rate higher our cohort than previously reported, infections rare. Our data emphasizes confirmative testing should be performed infected an underlying pathology leading admission.

Язык: Английский

---

Experiences of working as a clinical nurse while pregnant during the coronavirus disease-2019 pandemic: a qualitative study

BMC Nursing, Год журнала: 2025, Номер 24(1)

Опубликована: Фев. 3, 2025

Abstract Background Working as a pregnant clinical nurse might experience range of challenges, such significant anatomical and physiological changes well emotional cognitive changes. That be particularly obvious under the historical background coronavirus disease-2019 (COVID-19) pandemic. However, dearth studies has explored experiences working during this special period. This study aimed to explore while COVID-19 Methods A descriptive qualitative design was selected. Purposive sampling, combined with maximum variation strategy snowball were utilized identify select participants from tertiary-teaching hospitals, specialized community hospitals in Zhejiang Province, southeastern China. Online semi-structured individual interviews used collect data, conventional content analysis analyze data. Results Eleven Chinese nurses mean age 31.8 years, ranging 26 40 participated study. Four themes twelve subthemes emerged: (1) still adhering work despite being pandemic; (2) pregnancy pandemic is an ordinary nurse; (3) staying life phase mother; (4) growth gains mother. Conclusion The suffered various difficulties Managers, occupational health other system leaders, policymakers should aware importance establishing environment that guarantees safe continued pregnancy. Future focus on establishment specific guidelines manuals regarding how worked, development self-protection interventions Moreover, research moral stigma bullying nursing deserves further exploration. Clinical trial number Not applicable.

Язык: Английский

---

Updates on Auditory Outcomes of COVID-19 and Vaccine Side Effects: An Umbrella Review

Journal of Speech Language and Hearing Research, Год журнала: 2025, Номер 68(3), С. 1311 - 1332

Опубликована: Фев. 21, 2025

This umbrella review synthesizes and discusses systematic reviews (SRs) meta-analyses (MAs) on auditory outcomes associated with COVID-19 infection vaccination side effects. It is innovative in offering a comprehensive synthesis of evidence across adults infants while summarizing vaccine-related literature search followed the Preferred Reporting Items for Systematic Reviews Meta-Analyses 2020 guidelines, no restrictions population age or symptom severity. Four electronic databases were searched from their inception to October 2024. The Assessment Multiple 2 checklist Risk Bias tool used assess quality risk bias. identified 534 articles, narrowed down 14 SRs following full-text review: Nine focused COVID-19; two, born mothers infected during pregnancy; three, effects vaccination. A random-effects model revealed significantly high pooled estimates hearing loss (5.0%, 95% CI [1.0, 9.0], p < .012, three MAs, N = 21,932) tinnitus (13.5%, [5.9, 21.1], ≤ .001, four 36,236) adults. However, current nonhospitalized patients indicates that symptoms often improve after recovery. Studies also show low rate whose contracted pregnancy. Similarly, whereas has been linked tinnitus, these are rare, most experience improvement within weeks months. Evidence suggests adults, although remain rare newborns caution warranted due limitations variability studies.

Язык: Английский

---

In-Utero Maternal-to-Fetal Transmission of COVID-19: An Immunological and Virological Study in the Eastern Province of Saudi Arabia

Infection and Drug Resistance, Год журнала: 2025, Номер Volume 18, С. 1393 - 1403

Опубликована: Март 1, 2025

Background: Coronavirus disease 2019 (COVID-19) is a respiratory illness caused by SARS-CoV-2 (severe acute syndrome coronavirus 2). The pandemic potential of the virus along with its severity posed threat to all individuals particularly pregnant women. Multiple studies suggested possibility vertical transmission COVID-19 variable findings. Aim: This study aims assess frequency and identify maternal neonatal complications. Materials Methods: A retrospective 17 months for women attending delivery who tested positive using polymerase chain reaction (PCR) (n = 80) their neonates 81) were both SARS-CoV2 PCR viral IgG IgM antibodies detection immunochromatography. matched control group negative mothers 51) was included. All testing done within 24– 48 hours, immediately completely separated from as per hospital policy. Results: total 263 included in study. Out 80 mothers, 4 (5%) had one (1.3%) neonates. commonest presentation cough (11.4%) dyspnea (10%). In addition, need ICU admission antibiotics usage significantly higher (p value 0.042, 0.003 respectively). On other hand, risk low birth weight NICU < 0.001). Conclusion: study, unique infection protocol managing PCR-positive use immunological neonates, provides evidence in-utero transmission, interpretation results should be conjunction WHO categorization timing mother-to-fetal transmission. Further are needed impact genetic evolution on maternal–fetal Keywords: SARS-CoV-2, in-utero, IgM,

Язык: Английский

---

Placental lesions induced by Omicron SARS-CoV-2 in a pregnant woman treated with anti-CD20

Placenta, Год журнала: 2025, Номер unknown

Опубликована: Март 1, 2025

Язык: Английский

---

COVID-19 Vertical Transmission from Mothers to Neonates: A Systematic Review and Meta-Analysis of 204 Studies

Journal of Infection and Public Health, Год журнала: 2025, Номер unknown, С. 102825 - 102825

Опубликована: Май 1, 2025

Язык: Английский

---

To be soft again: A phenomenological study of uncertainty and resilience in childbearing during the COVID-19 pandemic

Women s Health, Год журнала: 2025, Номер 21

Опубликована: Июнь 1, 2025

Background: During the COVID-19 pandemic, uncertainty was exacerbated in experiences of pregnancy and childbirth as people navigated through uncharted territory. Building resilience may be one effective way to cope. However, for those who carry a heavier burden upholding others, societal expectation “toughness” ability endure lead an appearance resilience, while on inside, well-being compromised. Objectives: This study is part larger phenomenological that explored broad research question: What lived experience childbearing during pandemic? Specific themes are reported with aim provide deeper exploration role they play persons’ lives. Design: utilized interpretive design, which allowed in-depth participants’ implicit meanings experiences. Methods: Participants were either currently or recently pregnant had given birth since pandemic began recruited from U.S. national survey. Twenty-two ethnically, racially, geographically diverse women interviewed via Zoom English Spanish. Results: The text revealed rich narratives unfolding vis-à-vis direct contracting COVID-19, concerns regarding vaccination, effects public health restrictions impacting pregnancy, birth, postpartum also shared how courage humility contributed their overall masked others. Conclusion: When considering complexity women’s lives contemporary society along demands motherhood facilitate deeply felt resulting well-being, interventions must multi-pronged lessen pressures superwoman and/or supermom change norm level persons have option soft again .

Язык: Английский

---

Impact of COVID-19 on pregnant women's health: Consequences in obstetrics two years after the pandemic

Journal of Reproductive Immunology, Год журнала: 2023, Номер 158, С. 103981 - 103981

Опубликована: Июнь 15, 2023

Язык: Английский

---

Management of neonates with maternal prenatal coronavirus infection and influencing factors

Pediatric Research, Год журнала: 2023, Номер 95(2), С. 436 - 444

Опубликована: Окт. 19, 2023

Язык: Английский

---

A Post-Pandemic Insight on The Covid-19 and Pregnancy in Malaysia

Journal of Angiotherapy, Год журнала: 2024, Номер 8(2)

Опубликована: Фев. 20, 2024

A December 2023 COVID-19 outbreak in Southeast Asia prompted an update on Malaysia's existing understanding of and pregnancy. Research suggests that increases the risk adverse maternal perinatal outcomes. Pregnant women are more susceptible to due physiological changes coagulation, immune, respiratory, cardiovascular systems during Evidence indicates pregnant patients at increased for severe illness intensive care unit (ICU) admission. Stillbirth, neonatal death, preterm labour some most often reported foetal Data shows vertical transmission is possible but rare. Currently, vaccination remains effective safest strategy protecting groups from illness, complications, death. Although Malaysia has no plans reinstate its movement control order, following a sharp rise cases across country, Ministry Health (MOH) prepared five-point as well updated Management Guidelines, including therapeutic management with COVID-19. The MOH encourages safe public practices general measures vaccinations, wearing masks, maintaining hand hygiene. This review provides important insights into pregnancy Malaysia, susceptibility pregnancy, outcomes COVID-19, newborn, treatment breastfeeding, unvaccinated lactating mothers Malaysia.

Язык: Английский

---