Surface plasmon resonance-enhanced photoelectrochemical immunoassay with Cu-doped porous Bi2WO6 nanosheets

Talanta, Год журнала: 2024, Номер 273, С. 125863 - 125863

Опубликована: Март 6, 2024

Язык: Английский

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Evaluation of the difference in adsorption of amphetamine-type drugs on deep eutectic solvent-functionalized graphene oxide/ZIF-67 composite: Experiment and theoretical calculations

Environmental Research, Год журнала: 2024, Номер 249, С. 118356 - 118356

Опубликована: Фев. 6, 2024

Язык: Английский

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MicroRNA Sensors Based on CRISPR/Cas12a Technologies: Evolution From Indirect to Direct Detection

Critical Reviews in Analytical Chemistry, Год журнала: 2024, Номер unknown, С. 1 - 17

Опубликована: Март 15, 2024

MicroRNA (miRNA) has emerged as a promising biomarker for disease diagnosis and potential therapeutic targets drug development. The detection of miRNA can serve noninvasive tool in diseases predicting prognosis. CRISPR/Cas12a system great nucleic acid due to its high sensitivity specificity, which been developed be versatile acid-based various fields. However, conversion from RNA DNA with or without amplification operation is necessary based on system, because dsDNA containing PAM sequence ssDNA traditionally considered the activator Cas12a. Until recently, direct by reported. In this review, we provide an overview evolution biosensors indirect direct, would beneficial development CRISPR/Cas12a-based sensors better performance miRNA.

Язык: Английский

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“Two-in-One” PtPdCu Trimetallic Multifunctional Nanoparticles-Mediated Dual-Signal-Integrated Aptasensor for Ultradetection of Enrofloxacin

ACS Applied Materials & Interfaces, Год журнала: 2024, Номер 16(17), С. 22704 - 22714

Опубликована: Апрель 19, 2024

Balancing the accuracy and simplicity of aptasensors is a challenge in their construction. This study addresses this issue by leveraging remarkable loading capacity peroxidase-like catalytic activity PtPdCu trimetallic nanoparticles, which reduces reliance on precious metals. A dual-signal readout aptasensor for enrofloxacin (ENR) detection designed, incorporating DNA dynamic network cascade reactions to further amplify output signal. Exploiting strong they are self-assembled with thionine (Thi) form signal label capable generating signals two independent modes. The exhibits excellent enzyme-like enhances electron transfer capabilities. Differential pulse voltammetry (DPV) square-wave (SWV) employed independently read from oxidation–reduction reaction Thi oxidation hydroquinone (HQ) benzoquinone (BQ) H2O2. introduced modularizes sample processing electrode surface generation, avoiding contamination efficiently increasing catalyzed hairpin assembly (CHA) cycle. Under optimized conditions, developed demonstrates limits 0.112 (DPV mode) 0.0203 pg/mL (SWV mode). Additionally, sensor successfully detected real samples, expanding avenues designing dual-mode amplification strategies.

Язык: Английский

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Advances in bismuth utilization for biomedical applications – From a bibliometric perspective

Coordination Chemistry Reviews, Год журнала: 2024, Номер 517, С. 215988 - 215988

Опубликована: Июнь 12, 2024

Язык: Английский

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