A coumarin-based near infrared fluorescent probe for the detection of hydrogen sulfide/sulfur dioxide and mitochondrial viscosity

Sensors and Actuators B Chemical, Год журнала: 2024, Номер 418, С. 136243 - 136243

Опубликована: Июль 4, 2024

Язык: Английский

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NQO1 and viscosity tandemly responsive NIR fluorescent probe for tumor imaging and monitoring tumor apoptosis

Sensors and Actuators B Chemical, Год журнала: 2024, Номер 418, С. 136247 - 136247

Опубликована: Июль 4, 2024

Язык: Английский

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Near-infrared probes based on naphthyridine malononitrile units for monitoring the viscosity fluctuation of lysosomes and endoplasmic reticulum during autophagy and ferroptosis

Microchemical Journal, Год журнала: 2025, Номер unknown, С. 113344 - 113344

Опубликована: Март 1, 2025

Язык: Английский

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A wash-free fluorescent probe with red-emission for monitoring mitochondrial viscosity changes during cellular metabolism and different death processes

Spectrochimica Acta Part A Molecular and Biomolecular Spectroscopy, Год журнала: 2025, Номер 333, С. 125884 - 125884

Опубликована: Фев. 10, 2025

Язык: Английский

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Development of a Near-Infrared Probe for Enhancing Cancer Therapy by Mitigating Pyroptosis-Induced Inflammation

Analytical Chemistry, Год журнала: 2025, Номер unknown

Опубликована: Фев. 26, 2025

Pyroptosis, a specialized cell death mechanism crucial in cancer therapy, is distinct from apoptosis and primary necrosis. It linked to inflammation reactive oxygen species, particularly peroxynitrite (ONOO-), which implicated disease. Monitoring pyroptosis challenging due its connection with cellular polarity the tumor environment. In this research, we developed near-infrared probe, PBQI, highly sensitive responsive ONOO- fluctuations. PBQI targets mitochondria lipid droplets, enabling real-time tracking of pyroptosis-associated subcellular alterations. was found differentiate between normal cells during triggered by cisplatin metformin. To mitigate pyroptosis-induced inflammation, disulfiram used as an inhibitor, significantly alleviating excessive inflammation. This study highlights PBQI's utility studying interplay polarity, ONOO-, pyroptosis, contributes development more targeted therapies that optimize pyroptosis's antitumor benefits while minimizing inflammatory side effects.

Язык: Английский

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Molecular engineering of a D-A-type fluorescent probe with AIE properties for c-MYC G-Quadruplex DNA

Dyes and Pigments, Год журнала: 2025, Номер unknown, С. 112814 - 112814

Опубликована: Апрель 1, 2025

Язык: Английский

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In vitro and in vivo bioimaging by Quinoline conjugated probes and dyes

Coordination Chemistry Reviews, Год журнала: 2025, Номер 536, С. 216654 - 216654

Опубликована: Апрель 10, 2025

Язык: Английский

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Novel quinoline-based chemosensor as specific fluorescence sensing of copper ions in cancer cells and for organelle-specific imaging application

Inorganica Chimica Acta, Год журнала: 2024, Номер 575, С. 122440 - 122440

Опубликована: Ноя. 6, 2024

Язык: Английский

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A ratiometric fluorescent probe based on FRET mechanism for pH and its cell imaging

Dyes and Pigments, Год журнала: 2024, Номер 233, С. 112544 - 112544

Опубликована: Ноя. 15, 2024

Язык: Английский

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A Novel Coumarin-Based Near Infrared Fluorescent Probe for the Detection of Hydrogen Sulfide/ Sulfur Dioxide and Mitochondrial Viscosity

Опубликована: Янв. 1, 2024

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Язык: Английский

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