A novel molecularly imprinted electrochemical sensor from poly (3, 4-ethylenedioxythiophene)/chitosan for selective and sensitive detection of levofloxacin

International Journal of Biological Macromolecules, Год журнала: 2024, Номер 267, С. 131321 - 131321

Опубликована: Апрель 1, 2024

Язык: Английский

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A Wearable Electrochemical Sensor Based on a Molecularly Imprinted Polymer Integrated with a Copper Benzene-1,3,5-Tricarboxylate Metal-Organic Framework for the On-Body Monitoring of Cortisol in Sweat

Polymers, Год журнала: 2024, Номер 16(16), С. 2289 - 2289

Опубликована: Авг. 13, 2024

Owing to their potential transform traditional medical diagnostics and health monitoring, wearable biosensors have become an alternative evolutionary technology in the field of care. However, it is still necessary overcome some key technique challenges, such as selectivity, sensitivity, stability biometric identification. Herein, a novel, electrochemical sensor based on molecularly imprinted polymer (MIP) integrated with copper benzene-1,3,5-tricarboxylate metal-organic framework (MOF) was designed for detection stress through on-body monitoring cortisol sweat. The MOF used substrate MIP deposition enhance sensitivity sensor. consisted two layers, microfluidic layer top spontaneous sweating modified electrode bottom sensing. measured levels by detecting current change that occurred when target molecules bound cavities, using Prussian blue nanoparticles embedded REDOX probe. proposed exhibited linear range 0.01-1000 nM limit 0.0027 nM, favorable specificity over other analogies. This facile anti-body free showed excellent stability, can be successfully applied situ monitoring.

Язык: Английский

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Molecularly and ionically imprinted polymers-based chemical sensors in chemical assays

Chemical Engineering Journal, Год журнала: 2024, Номер unknown, С. 156315 - 156315

Опубликована: Сен. 1, 2024

Язык: Английский

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Digital SERS immunoassay of Interleukin-6 based on Au@Ag-Au nanotags

Biosensors and Bioelectronics, Год журнала: 2024, Номер 270, С. 116973 - 116973

Опубликована: Ноя. 20, 2024

Язык: Английский

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Neurodegenerative diseases early detection and monitoring system for point-of-care applications

Microchemical Journal, Год журнала: 2024, Номер 208, С. 112280 - 112280

Опубликована: Дек. 2, 2024

Язык: Английский

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N-Doped Porous Carbon Synergistic Freezing-Induced DNA with Catalyzed Hairpin Assembly Enables Electrochemical One-Pot Detection of Pathogen in Food Samples

Journal of Agricultural and Food Chemistry, Год журнала: 2025, Номер unknown

Опубликована: Фев. 7, 2025

A DNA electrochemical interface biosensor based on screen-printed carbon electrodes (SPCEs) holds promise for point-of-care testing (POCT) detection of pathogens in food safety. Nevertheless, SPCE commonly has a rough surface and suffers from relatively low electron transfer rate, disorder capture probes (CPs), the steric hindrance effect target nucleic acid binding. These issues lead to sensitivity. Herein, simple rapid N-doped porous (NPC)-modified freezing-directed combined with catalyzed hairpin assembly (CHA) was constructed one-pot samples without time-consuming growth cultures. The by modified NPC enhanced properties, CP designed CHA stably fixed electrode high hybridization efficiency. Moreover, signals amplified enable selective sensitive washing steps. This method is wide linear range 101 107 CFU/mL limit 5 Escherichia coli shows specificity against other coexisting pathogens. whole complex performed only within 60 min sample-to-answer, which great potential POCT

Язык: Английский

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Carbon black imprinted o-diaminobenzene sensing platform for sensitive electrochemical detection of interleukin 6

Analytical Sciences, Год журнала: 2025, Номер unknown

Опубликована: Фев. 21, 2025

Язык: Английский

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Gold Nanoparticles/Graphdiyne as Sensing Substrate Coupled with UiO-66/ferrocene as Signaling-Amplifier for Sandwich-Type Electrochemical Immunosensing of Interleukin-6

Journal of The Electrochemical Society, Год журнала: 2025, Номер 172(3), С. 036503 - 036503

Опубликована: Март 1, 2025

Interleukin-6 (IL-6) is a common proinflammatory cytokine and can be adopted as an important biomarker for several diseases including nasopharynx cancer, pancreatitis, infections, cardiovascular. It thus necessary to design effective method monitoring IL-6. Herein, by preparing gold nanoparticles/graphdiyne (Au/GRD) nanohybrid with simple electroless deposition the sensing substrate UiO-66 metal–organic frameworks/ferrocene (UiO/Fc) signaling-amplifier, highly efficient sandwich-type electrochemical immunosensing (SEI) platform was proposed IL-6 determination. The superior electrical properties, easy preparation, high surface area, stability of Au/GRD make it desirable immobilize primary antibody Meanwhile, unique structure beneficial immobilizing Fc probe secondary antibody. By optimizing experimental conditions, current obtained at as-designed SEI increases along increase, related linearity 0.5 pg ml −1 –1200.0 coupled low detection limit 0.2 . expected based on UiO/Fc shows potential applications analysis.

Язык: Английский

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Developing an applicable electrochemical micro-sensor for highly specific detecting chlortetracycline in water with o-phenylenediamine-based molecularly imprinted polymer

Microchemical Journal, Год журнала: 2025, Номер unknown, С. 113846 - 113846

Опубликована: Май 1, 2025

Язык: Английский

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Highly sensitive label-free Immunosensor based on 5-sulfosalicylic acid doped poly(2-chloroaniline) for detection of CA72–4 in gastric Cancer

Bioelectrochemistry, Год журнала: 2025, Номер unknown, С. 108997 - 108997

Опубликована: Май 1, 2025

Язык: Английский

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