Microchemical Journal, Год журнала: 2024, Номер unknown, С. 112462 - 112462
Опубликована: Дек. 1, 2024
Язык: Английский
Analytical Chemistry, Год журнала: 2025, Номер unknown
Опубликована: Март 17, 2025
In this work, a photoelectrochemical (PEC) sensor for ovarian cancer detection was constructed based on TiO2/poly(5-formylindole) (P5FIn)heterojunction using cascade amplification. The combined of multiple markers instead single mode can improve diagnostic accuracy. photoelectron conversion efficiency and photocurrent response were significantly improved by the reaction detector glutathione (GSH) with cystine. 17β-Estradiol (E2) had negative effect PEC response, reducing signal, ultimately realizing sensitive GSH E2. good performance E2, linear range (LDR) 0.5–1000 μM, limits (LOD) 0.167 μM 0.1224 pM, respectively, 0.0003671–36.71 nM. Meanwhile, also has analytical capability, signal amplification strategy potential development prospect in disease detection.
Язык: Английский
Процитировано
3
Angewandte Chemie International Edition, Год журнала: 2025, Номер unknown
Опубликована: Фев. 12, 2025
Abstract Nanozymes with atomically dispersed metal sites (ADzymes), especially single‐atom nanozymes, have attracted widespread attention in recent years due to their unique advantages mimicking the active of natural enzymes. These nanozymes not only maximize exposure catalytic but also possess superior activity performance, achieving challenging reactions. position ADzymes as highly promising candidates field sensing and biosensing. This review summarizes classification properties ADzymes, systematically highlighting some typical regulation strategies involving central metal, coordination environment, etc., achieve catalytical activity, specificity, multifunctionality. Then, we present advances different fields, including colorimetry, fluorescence, electrochemistry, chemiluminescence, photoelectrochemistry, electrochemiluminescence. Taking advantage resultant show great potential goal sensitivity, selectivity accuracy for detection various targets. Specifically, underlying mechanisms terms signal amplification were discussed detail. Finally, current challenges perspectives on development advanced are discussed.
Язык: Английский
Процитировано
2
Bioelectrochemistry, Год журнала: 2024, Номер 160, С. 108773 - 108773
Опубликована: Июль 3, 2024
Язык: Английский
Процитировано
8
Microchimica Acta, Год журнала: 2025, Номер 192(2)
Опубликована: Янв. 18, 2025
Язык: Английский
Процитировано
0
Angewandte Chemie, Год журнала: 2025, Номер unknown
Опубликована: Фев. 12, 2025
Abstract Nanozymes with atomically dispersed metal sites (ADzymes), especially single‐atom nanozymes, have attracted widespread attention in recent years due to their unique advantages mimicking the active of natural enzymes. These nanozymes not only maximize exposure catalytic but also possess superior activity performance, achieving challenging reactions. position ADzymes as highly promising candidates field sensing and biosensing. This review summarizes classification properties ADzymes, systematically highlighting some typical regulation strategies involving central metal, coordination environment, etc., achieve catalytical activity, specificity, multifunctionality. Then, we present advances different fields, including colorimetry, fluorescence, electrochemistry, chemiluminescence, photoelectrochemistry, electrochemiluminescence. Taking advantage resultant show great potential goal sensitivity, selectivity accuracy for detection various targets. Specifically, underlying mechanisms terms signal amplification were discussed detail. Finally, current challenges perspectives on development advanced are discussed.
Язык: Английский
Процитировано
0
Polyhedron, Год журнала: 2025, Номер unknown, С. 117545 - 117545
Опубликована: Апрель 1, 2025
Язык: Английский
Процитировано
0
TrAC Trends in Analytical Chemistry, Год журнала: 2025, Номер unknown, С. 118277 - 118277
Опубликована: Апрель 1, 2025
Язык: Английский
Процитировано
0
ACS Applied Materials & Interfaces, Год журнала: 2025, Номер unknown
Опубликована: Май 22, 2025
The repair of large bone defects remains a significant challenge in the field orthopedics, as traditional substitutes face issues such limited supply and structural incompatibility. Therefore, development novel biomaterials to promote is great significance. This study proposes composite material based on gelatin/alginate dual-network hydrogel scaffold (Gel/AlgMA), which regulates oxidative stress local microenvironment by loading cerium metal-organic frameworks (Ce-UiO-66) resveratrol (Res). ions Ce-UiO-66 exhibit excellent antioxidant properties their multivalent states, capable scavenging excess reactive oxygen species (ROS), improving mitochondrial function, enhancing stability through polydopamine (PDA) coating. Gel/Alg@Ce-Res/PDA was prepared via photopolymerization its vitro biocompatibility, properties, osteogenic potential were evaluated. results indicated that effectively scavenged ROS, alleviated stress, promoted proliferation differentiation osteoblasts. Moreover, vivo experiments further confirmed favorable effects defect repair. provides an innovative biomaterial design for treatment, with promising clinical application prospects.
Язык: Английский
Процитировано
0
Talanta, Год журнала: 2024, Номер 279, С. 126576 - 126576
Опубликована: Июль 15, 2024
Язык: Английский
Процитировано
3
Chinese Chemical Letters, Год журнала: 2024, Номер unknown, С. 110333 - 110333
Опубликована: Авг. 1, 2024
Язык: Английский
Процитировано
1