A Dual-Responsive Fluorescent Probe for Cancer Diagnostics via Simultaneous Detection of H2S and hNQO1

Sensors and Actuators B Chemical, Год журнала: 2025, Номер unknown, С. 137682 - 137682

Опубликована: Март 1, 2025

Язык: Английский

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Ultrasensitive, Online Detection of Endogenous H2s by a Novel Ratiometric Fluorescent Approach

Опубликована: Янв. 1, 2025

Endogenous hydrogen sulfide (H2S) is a crucial biological signaling molecule in the mammals. Numerous H2S sensing methods have been developed, yet there remains an urgent need for portable, online and sensitive detection of complex samples. Herein, ratiometric fluorescent optical fiber sensor was designed ultrasensitive, H2S, using nanohybrids electrostatically self-assembled from silicon quantum dots gold nanoclusters (AuNCs@SiQDs nanohybrids). The nanohybrids, acting as probe, exhibited specific response to H2S. mechanism involved static quenching effect on AuNCs fluorescence resonance energy transfer between SiQDs AuNCs. showed good linear concentration 0.01 ~ 100 μM, with ultralow limit 4.33 nM. also successfully employed rapid real serum samples, without tedious preprocessing. This approach offers portable efficient technique on-line ultrasensitive measurement well determination H2S-mediated biomolecules. method boasts high sensitivity selectivity, strong anti-interference capability, portability, practicality, ease production, making it significant disease research emergency analysis.

Язык: Английский

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A Near-Infrared Fluorescent Probe with a Large Stokes Shift for Detecting Hydrogen Sulfide in Environmental Waters, Wine Samples, and Living Systems

Journal of Agricultural and Food Chemistry, Год журнала: 2025, Номер unknown

Опубликована: Фев. 12, 2025

Hydrogen sulfide (H2S) is closely related to physiological diseases, environmental pollution, food safety, and plant growth. Herein, a new nopinone-based near-infrared fluorescent probe has been developed detect H2S with superior performance, including large Stokes shift, low detection limit, good selectivity, fast response time. NPD-H2S was used in water wine samples quantitatively. In addition, could be fabricate nanofiber membranes as portable tool for sensitively detecting vapor using smartphone. Moreover, effectively image HeLa cells, MCF-7 zebrafish. More importantly, the monitored presence of upregulation processes Arabidopsis thaliana under salt stress by bioimaging. This work provides concept intervention external stresses cultivation. Therefore, can monitor fluctuation environment living systems.

Язык: Английский

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Study of excited-state relaxation mechanisms for two 1,8-naphthalimide-based derivatives detecting of hydrogen sulfide

Spectrochimica Acta Part A Molecular and Biomolecular Spectroscopy, Год журнала: 2025, Номер unknown, С. 126202 - 126202

Опубликована: Апрель 1, 2025

Язык: Английский

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On-site quantitative measurement of hydrogen sulfide in crop and food samples using a ratiometric near-infrared fluorescent probe coupled with a portable optical data acquisition device

Microchemical Journal, Год журнала: 2025, Номер unknown, С. 113645 - 113645

Опубликована: Апрель 1, 2025

Язык: Английский

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Hydrothermal synthesis of Ag-doped WO3-based H2S room temperature sensors: Unprecedented high and fast response

Sensors and Actuators B Chemical, Год журнала: 2025, Номер unknown, С. 137811 - 137811

Опубликована: Апрель 1, 2025

Язык: Английский

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Ratiometric fluorophores to ONOO– in living cells and monitoring endothelial dysfunction

Sensors and Actuators B Chemical, Год журнала: 2024, Номер 426, С. 137068 - 137068

Опубликована: Дек. 7, 2024

Язык: Английский

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Highly Sensitive Ratiometric Fluorescence Monitoring Hypoxanthine in Food Based on the Full Utilization of Enzyme-Catalyzed Oxidation Products

Опубликована: Янв. 1, 2024

Язык: Английский

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