Journal of Electroanalytical Chemistry, Год журнала: 2024, Номер unknown, С. 118722 - 118722
Опубликована: Окт. 1, 2024
Язык: Английский
Microchimica Acta, Год журнала: 2025, Номер 192(4)
Опубликована: Март 12, 2025
Язык: Английский
Процитировано
1
ACS Materials Au, Год журнала: 2024, Номер 5(1), С. 115 - 140
Опубликована: Ноя. 28, 2024
The delivery of molecules, such as DNA, RNA, peptides, and certain hydrophilic drugs, across the epidermal barrier poses a significant obstacle. Microneedle technology has emerged prominent area focus in biomedical research because its ability to deliver wide range biomolecules, vaccines, medicines, other substances through skin. Microneedles (MNs) form microchannels by disrupting skin's structure, which compromises function, facilitating easy penetration drugs into These devices enhance administration many therapeutic skin, enhancing their stability. Transcutaneous medications using microneedle patch offers advantages over conventional drug methods. containing active can be stimulated different internal external factors result regulated release substances. To achieve efficient desired location, it is necessary consider design needles with appropriate optimized characteristics. choice materials for developing manufacturing these vital determining pharmacodynamics pharmacokinetics delivery. This article provides most recent update overview numerous systems that utilize activators stimulate components from microneedles. Further, discusses utilized producing microneedles strategies important managing drugs. An explanation commonly employed fabrication techniques applications electronics, particularly integrated systems, discussed. successfully implement clinical settings, essential comprehensively assess several factors, biocompatibility, stability, safety, production cost. Finally, an in-depth review criteria difficulties potential future direction delivering monitoring diseases explored.
Язык: Английский
Процитировано
3
Optics Express, Год журнала: 2025, Номер 33(2), С. 2475 - 2475
Опубликована: Янв. 7, 2025
pH is an important physiological parameter within organisms, playing a crucial role in functional activities cells and tissues. Among various sensing methods, optical fiber sensors have gained wide attention due to their unique advantages. However, current silica fiber-based face some challenges such as weak biocompatibility, low biological safety, complex or unstable surface modification. Herein, we develop what believe be novel sensor based on CdSe/ZnS quantum dots-doped polymer microprobe (POF MP) grown at the end of using free radical photopolymerization process, which has advantages significant compactness, high flexibility, good easy functionalization, structural stability safety. Moreover, size POF MP are controllable, highly for applications requiring specific probe sizes those used special terrains. The proposed demonstrated sensitivity 0.18097/pH range from 4.5 9.0, while it exhibits linear correlation between fluorescence intensity value ( R 2 = 0.99448) reversibility reusability. This offers promising solution monitoring environments, contributing advancements biosensing, microenvironment monitoring, potential therapeutic applications.
Язык: Английский
Процитировано
0
Sensors and Actuators B Chemical, Год журнала: 2025, Номер unknown, С. 137949 - 137949
Опубликована: Май 1, 2025
Язык: Английский
Процитировано
0
Chemical Engineering Journal, Год журнала: 2025, Номер unknown, С. 163870 - 163870
Опубликована: Май 1, 2025
Язык: Английский
Процитировано
0
TrAC Trends in Analytical Chemistry, Год журнала: 2025, Номер unknown, С. 118310 - 118310
Опубликована: Май 1, 2025
Язык: Английский
Процитировано
0
Journal of Electroanalytical Chemistry, Год журнала: 2024, Номер unknown, С. 118722 - 118722
Опубликована: Окт. 1, 2024
Язык: Английский
Процитировано
0