Acta Physica Sinica, Год журнала: 2025, Номер 74(14), С. 0 - 0
Опубликована: Янв. 1, 2025
The rapid advancement of flexible electronics has driven innovation in wearable respiratory monitoring devices, yet challenges remain achieving medical-grade precision for quantitative pulmonary function assessment. This study integrates water molecule-responsive sensing technology, and a cloud-based intelligent analysis platform to develop the first system (SFMS). By leveraging synergistic effect bionic microcavity differential pressure humidity-sensitive interfaces, combined with difference-flux dynamic model, enables simultaneous resolution peak expiratory flow (PEF) forced vital capacity (FVC), accurately deriving core indicators such as FEV1/FVC. Clinical validation across 454 cases demonstrated high consistency gold-standard spirometry (intraclass correlation coefficient [ICC] = 0.93–0.97), 89.7% sensitivity 92.3% specificity differentiating chronic obstructive disease (COPD) from asthma. Technologically, this work pioneers testing, eliminating dependence on specialized operators through an embedded edge computing architecture that supports real-time cloud data interaction. establishes disease-specific profiles multi-parametric physiological analysis. Practically, its low cost, portability, user-friendly operation facilitate seamless integration into primary healthcare home health management, providing technical tools hierarchical diagnosis treatment diseases. Aligned WHO's Respiratory Health Action Plan, universal advance early screening long-term management. With significant clinical translation potential, it offers groundbreaking solution building comprehensive prevention control framework
Язык: Английский