Decoding Infection and Transmission, Год журнала: 2024, Номер 2, С. 100030 - 100030
Опубликована: Янв. 1, 2024
Язык: Английский
BMC Cancer, Год журнала: 2025, Номер 25(1)
Опубликована: Фев. 3, 2025
Язык: Английский
Процитировано
2
Cancers, Год журнала: 2025, Номер 17(5), С. 892 - 892
Опубликована: Март 5, 2025
Thyroid cancer is a rising concern in children and adolescents, with unique biological behaviors compared to adults. This study aimed explore the epidemiological trends, pathological features, regional disparities of thyroid this population using data from Global Burden Disease (GBD) 2021. Data on incidence mortality 1990 2021 were extracted for individuals under 20 years old. The estimated annual percentage change (EAPC) was calculated evaluate temporal trends. Sociodemographic Index (SDI) applied assess variations. Future trends projected Bayesian age-period-cohort model. From 2021, global adolescents increased significantly, an EAPC 1.17%. Low-SDI regions exhibited highest rise (EAPC: 2.19%), while high-SDI experienced slight decline -0.69%). Mortality decreased globally -0.27%), notable reductions high- middle-SDI but stable or increasing rates low-SDI regions. Females consistently higher across all SDI levels, males showed rates. projections suggest steady through 2050. persistent highlight need targeted public health interventions. Regions low socioeconomic development require prioritized strategies address growing burden. These findings provide crucial insights early diagnosis, treatment optimization, policy formulation.
Язык: Английский
Процитировано
0
Clinical and Experimental Pharmacology and Physiology, Год журнала: 2025, Номер 52(5)
Опубликована: Апрель 5, 2025
ABSTRACT Background Asthma presents a significant challenge to the global healthcare systems and imposes heavy socioeconomic burden. Previous studies had geographical limitations lacked comprehensive analysis. The study utilises data from 2021 Global Burden of Disease ( GBD ) assess global, regional, national burden asthma 1990 2021. It examines disease trends, highlights health inequalities aims provide scientific evidence for future public strategies optimisation resource allocation. Methods Data were used estimate incidence, prevalence, mortality, disability‐adjusted life years (DALYs) across 21 regions 204 countries territories Temporal trends analysed, relationship between socio‐demographic index (SDI) was examined using smoothing spline model. Analyses included slope inequality concentration disparities, frontier analysis achievable outcomes based on development levels, decomposition identify drivers changes in DALYs number. Results Over past three decades, age‐standardised has declined, with mortality DALY rates decreasing by 46% 44%, respectively. However, absolute number deaths increased 17%, particularly among females, especially low low‐middle SDI regions. Significant persist, high‐SDI benefiting better control, while low‐SDI face disproportionate burdens due disparities. Frontier gaps current optimal require investment control. Aging, population growth, epidemiological are key trends. High body mass (BMI) remains leading risk factor, smoking occupational exposures continue contribute significantly. Conclusions yet regional disparities experiencing higher limited access environmental risks. BMI, remain contributors, requiring targeted interventions lifestyle modifications.
Язык: Английский
Процитировано
0
Decoding Infection and Transmission, Год журнала: 2024, Номер 2, С. 100030 - 100030
Опубликована: Янв. 1, 2024
Язык: Английский
Процитировано
0