Engineering Spinal Cord and Peripheral Nerve Organoids: Strategies for Construction and Potential Applications for Regenerative Medicine in Neurotrauma DOI Creative Commons
Jiacan Su, Zhiwen Yan, Xiaoxuan Tang

и другие.

Engineering, Год журнала: 2025, Номер unknown

Опубликована: Май 1, 2025

Язык: Английский

Bioengineering innovations for neural organoids with enhanced fidelity and function DOI
Yubing Sun, Yoshiho Ikeuchi, Feng Guo

и другие.

Cell stem cell, Год журнала: 2025, Номер 32(5), С. 689 - 709

Опубликована: Май 1, 2025

Язык: Английский

Процитировано

0

Engineering blood–brain barrier microphysiological systems to model Alzheimer's disease monocyte penetration and infiltration DOI
Longjun Gu, Xiangdi Mao,

Chunhui Tian

и другие.

Biomaterials Science, Год журнала: 2025, Номер unknown

Опубликована: Янв. 1, 2025

We report the development of engineered human stem cell-derived blood-brain barrier microphysiological systems for modeling neuroinflammation in Alzheimers' disease.

Язык: Английский

Процитировано

0

Generation of Neural Organoids and Their Application in Disease Modeling and Regenerative Medicine DOI Creative Commons
Ruiqi Huang, Feng Gao, Liqun Yu

и другие.

Advanced Science, Год журнала: 2025, Номер unknown

Опубликована: Май 24, 2025

Abstract The complexity and precision of the human nervous system have posed significant challenges for researchers seeking suitable models to elucidate refractory neural disorders. Traditional approaches, including monolayer cell cultures animal models, often fail replicate intricacies tissue. advent organoid technology derived from stem cells has addressed many these limitations, providing highly representative platforms studying structure function embryonic brain spinal cord. Researchers induced organoids with regional characteristics by mimicking morphogen gradients in development. Recent advancements demonstrated utility disease modeling, offering insights into pathophysiology various disorders, as well field regeneration. Developmental defects due lack microglia or vascular systems are addressed. In addition induction methods, microfluidics is used simulate dynamic physiological environment; bio‐manufacturing technologies employed regulate physical signaling shape complex organs. These further expand construction strategies application scope organoids. With emergence new material paradigms advances AI, possibilities realm witnessed.

Язык: Английский

Процитировано

0

Mind over scaffold: Vascular network-inspired scaffolds for functionally mature neural organoids DOI
Yu Jung Shin,

Jacob Dairaghi,

Ying Zheng

и другие.

Опубликована: Май 1, 2025

Язык: Английский

Процитировано

0

Engineering Spinal Cord and Peripheral Nerve Organoids: Strategies for Construction and Potential Applications for Regenerative Medicine in Neurotrauma DOI Creative Commons
Jiacan Su, Zhiwen Yan, Xiaoxuan Tang

и другие.

Engineering, Год журнала: 2025, Номер unknown

Опубликована: Май 1, 2025

Язык: Английский

Процитировано

0