JOURNAL OF RENEWABLE MATERIALS,
Год журнала:
2024,
Номер
12(4), С. 643 - 666
Опубликована: Янв. 1, 2024
Polymers
from
renewable
resources
have
been
used
for
a
long
time
in
biomedical
applications
and
found
an
irreplaceable
role
some
of
them.Their
uses
increasing
because
their
attractive
properties,
contributing
to
the
improvement
life
quality,
mainly
drug
release
systems
regenerative
medicine.Formulations
using
natural
polymer,
nano
microscale
particles
preparation,
composites,
blends
chemical
modification
strategies
improve
properties
clinical
application.Although
many
studies
carried
out
with
these
polymers,
way
reach
market
is
only
very
few
them
become
commercially
available.Vegetable
cellulose,
bacterial
chitosan,
poly(lactic
acid)
starch
can
be
among
most
studied
polymers
biological
applications,
several
derivatives
already
established
market,
others
potential
such.In
this
scenario
work
aims
describe
routes
bench
perspectives
future
developments.
Heliyon,
Год журнала:
2024,
Номер
10(21), С. e39611 - e39611
Опубликована: Окт. 22, 2024
The
growing
need
for
developing
reliable
and
efficient
wound
dressings
has
led
to
recent
progress
in
designing
novel
materials
formulations
different
kinds
of
wounds
caused
by
traumas,
burns,
surgeries,
diabetes.
In
cases
extreme
urgency,
accelerating
recovery
is
high
importance
prevent
persistent
infection
biofilm
formation.
application
nanotechnology
this
domain
resulted
the
creation
distinct
nanoplatforms
highly
advanced
wound-healing
therapeutic
approaches.
Recently
developed
nanomaterials
have
been
used
as
antibacterial
agents
or
drug
carriers
control
infection.
present
review,
authors
aim
review
recently
published
research
on
effects
incorporating
emerging
into
investigate
their
roles
healing
process.
It
was
determined
that
metallic
nanoparticles
(NPs)
exhibit
antimicrobial
regenerative
properties,
metal
oxide
NPs
regulate
inflammation
promote
tissue
regeneration,
MXene
enhance
cell
adhesion
proliferation,
while
metal-organic
frameworks
(MOFs)
offer
controlled
delivery
capabilities.
Further
required
fully
understand
mechanisms
optimize
applications
these
healing.
ACS Applied Materials & Interfaces,
Год журнала:
2024,
Номер
16(25), С. 32128 - 32146
Опубликована: Июнь 14, 2024
Atopic
dermatitis
(AD)
is
a
chronic
inflammatory
skin
disease
with
complex
etiology
that
lacks
effective
treatment.
The
therapeutic
goals
include
alleviating
symptoms,
such
as
moisturizing
and
applying
antibacterial
anti-inflammatory
medications.
Hence,
there
an
urgent
need
to
develop
patch
effectively
alleviates
most
of
the
AD
symptoms.
In
this
study,
we
employed
"green"
cross-linking
approach
poly(vinyl
alcohol)
(PVA)
using
glycerol,
combined
it
polyacrylonitrile
(PAN)
fabricate
core–shell
(CS)
nanofibers
through
electrospinning.
Our
designed
structure
offers
multiple
benefits
core
ensures
controlled
drug
release
increases
strength
patch,
while
shell
provides
moisturization
exudate
absorption.
efficient
PVA
method
facilitates
inclusion
sensitive
molecules
fermented
oils.
vitro
studies
demonstrate
patches'
exceptional
biocompatibility
efficacy
in
minimizing
cell
ingrowth
into
CS
containing
argan
oil,
property
highly
desirable
for
easy
removal
patch.
Histological
examinations
conducted
on
ex
vivo
model
showed
nonirritant
properties
developed
patches.
Furthermore,
eradication
Staphylococcus
aureus
bacteria
confirms
potential
use
loaded
oil
or
norfloxacin,
separately,
infected
wounds.
application
patients,
including
one
AD,
demonstrated
ideal
effect.
This
innovative
shows
significant
promise
enhancing
life
quality
sufferers
by
improving
hydration
avoiding
infections.
Polymers for Advanced Technologies,
Год журнала:
2025,
Номер
36(3)
Опубликована: Март 1, 2025
ABSTRACT
In
this
study,
an
advanced
approach
to
synthesizing
wavy
ZnO–cellulose/chitosan@Cu
2+
nanocomposites
with
improved
functionality
and
conductivity
was
semi‐dissolving
chitosan
as
a
dual‐functionality
template.
The
template
method
uses
form
semi‐porous
structures
ethylene
glycol
the
solvent
crystallization
agent
for
hybrid
nanostructures.
surface
morphology,
stability,
conductive
nano‐nanostructures
significantly
improve
microstructural,
electrical,
antimicrobial
properties
of
Cu‐doped
ZnO–cellulose/chitosan
formed
composite
morphology
thermal
are
characterized
by
thermogravimetric
analysis
(TGA)
field
emission
scanning
electron
microscope
(SEM–EDX).
revealed
that
nanostructures
exhibited
steady‐state
plateau
at
low
frequencies,
which
represents
DC
conductivity,
while
transferred
frequency‐dependent
increase
higher
frequencies
due
hopping
conduction
mechanism,
Ac
conductivity.
impedance
spectroscopy
represented
Cole–Cole
indicated
non‐Debye
relaxation
processes.
equivalent
circuit
parameters
estimated
different
samples
showed
segmental
capacitance
(C1)
resistance
(R1)
values
ranging
from
4.5665
×
10
−11
F
2.3882
−10
4.9
6
Ω
5.244
5
Ω,
Cu
concentration
increased
zero
(A0)
4
mol%(A2),
respectively.
activity
using
Well
diffusion
technique.
demonstrated
inhibition
zone
diameters
19
31
mm
against
various
microorganisms,
including
30
Aspergillus
fumigatus
28
Escherichia
coli
A3
(6
mol%
).
These
findings
suggest
can
be
utilized
in
biomedical
fields
such
wound
dressings,
environmental
conservation,
food
packaging,
coatings.