Enhanced Acetaminophen Detection in Dolo-650 Tablets Using Electrocatalyst SnWO4-DNA Composite and Its Antibacterial Efficacy DOI
S. Kumaresan, S. Girija, Murugan Shibasini

и другие.

ACS Applied Bio Materials, Год журнала: 2025, Номер unknown

Опубликована: Июнь 4, 2025

Important aspects of this research include the development a very sensitive electrochemical sensor for acetaminophen (AMP) in D-650 tablets using SnWO4-DNA as sensing material. The surface area and porosity material were investigated Brunauer-Emmett-Teller (BET) instrument. Furthermore, TEM study was performed to observe presence DNA SnWO4, X-ray photoelectron spectroscopy (XPS) executed record chemical composition. is based on interaction between Sn2+ WO42- ions, which enhances catalytic activity active sites AMP created by DNA's nitrogen bases, promoting efficient electron transfer with high sensitivity. developed performs over detection much wider linear range (200 nM-1 mM), lower limit (55 nM), excellent reversibility. provides fast detection, suitable real-time monitoring. In addition, antibacterial properties composite are demonstrated effective inhibition growth Klebsiella pneumoniae Staphylococcus aureus, making multifunctional tool both applications. Being able provide simultaneous responses allows have dual capability medical diagnostics. sensitivity multifunctionality proposed make it an innovative promising approach that would wide application industry monitoring, pathogen control, potentially personalized medicine determining appropriate treatment regimen patients.

Язык: Английский

Synthesis, Characterization, and Electrochemical Applications of a New Lawsone Molecule: Potentiometric Determination of Cr(III) Ions with Low Detection Limit DOI Open Access
Oğuz Özbek,

Mehmet Emin Çakmak,

Kıymet Berkil Akar

и другие.

ChemistrySelect, Год журнала: 2025, Номер 10(13)

Опубликована: Март 28, 2025

Abstract In this study, a new lawsone derivative molecule (2) was synthesized, and sensors were prepared using it as electroactive material (ionophore). These exhibited selectivity towards Cr 3+ ions among different cationic species. The polymer membrane contained 3.0% ionophore, 64.0% dibutyl phthalate (DBP), 32.0% polyvinylchloride (PVC) 1.0% lipophilic additive (KT p ClPB). For novel potentiometric sensor, linear concentration range, Nernstian slope, detection limit, pH working range response time determined 1.0 × 10 −1 –1.0 −7 M, 21.8 ± 1.7 mV/decade, 7.65 −8 5.0–9.0 8 s, respectively. analytical application of the sensor carried out by determining in samples to which certain amounts added. newly developed able determine with very high recoveries.

Язык: Английский

Процитировано

1
Enhanced Acetaminophen Detection in Dolo-650 Tablets Using Electrocatalyst SnWO4-DNA Composite and Its Antibacterial Efficacy DOI
S. Kumaresan, S. Girija, Murugan Shibasini

и другие.

ACS Applied Bio Materials, Год журнала: 2025, Номер unknown

Опубликована: Июнь 4, 2025

Important aspects of this research include the development a very sensitive electrochemical sensor for acetaminophen (AMP) in D-650 tablets using SnWO4-DNA as sensing material. The surface area and porosity material were investigated Brunauer-Emmett-Teller (BET) instrument. Furthermore, TEM study was performed to observe presence DNA SnWO4, X-ray photoelectron spectroscopy (XPS) executed record chemical composition. is based on interaction between Sn2+ WO42- ions, which enhances catalytic activity active sites AMP created by DNA's nitrogen bases, promoting efficient electron transfer with high sensitivity. developed performs over detection much wider linear range (200 nM-1 mM), lower limit (55 nM), excellent reversibility. provides fast detection, suitable real-time monitoring. In addition, antibacterial properties composite are demonstrated effective inhibition growth Klebsiella pneumoniae Staphylococcus aureus, making multifunctional tool both applications. Being able provide simultaneous responses allows have dual capability medical diagnostics. sensitivity multifunctionality proposed make it an innovative promising approach that would wide application industry monitoring, pathogen control, potentially personalized medicine determining appropriate treatment regimen patients.

Язык: Английский

Процитировано

0