Microchemical Journal, Год журнала: 2025, Номер unknown, С. 113930 - 113930
Опубликована: Май 1, 2025
Язык: Английский
Microchemical Journal, Год журнала: 2025, Номер unknown, С. 113930 - 113930
Опубликована: Май 1, 2025
Язык: Английский
Journal of Energy Storage, Год журнала: 2025, Номер 115, С. 115985 - 115985
Опубликована: Фев. 27, 2025
Язык: Английский
Процитировано
1Frontiers in Bioengineering and Biotechnology, Год журнала: 2025, Номер 13
Опубликована: Фев. 28, 2025
Dopamine (DA) is a critical neurotransmitter that key in regulating motor functions, motivation, and reward-related behavior. Measuring both tonic (baseline, steady-state) phasic (rapid, burst-like) DA release essential for elucidating the mechanisms underlying neurological disorders, such as schizophrenia Parkinson’s disease, which are associated with dysregulated signaling. Carbon fiber microelectrodes (CFEs) considered gold standard measuring rapid changes due to their small size (5–10 µm), biocompatibility, flexibility, excellent electrochemical properties. However, achieving consistent results large-scale production of CFE arrays through manual fabrication poses significant challenges. We previously developed flexible glassy carbon (GC) microelectrode (MEAs) GC fiber-like MEAs (GCF MEAs) detection electrophysiology recording. also demonstrated feasibility fabricating MEA electrodes interconnects made from single homogeneous material, eliminating need metal interconnections addressing related concerns about electrical mechanical stability under prolonged cycling. Building on our prior experience, we now present double-etching microfabrication technique batch 10 μm × µm full fibers (fGCFs) fGCF arrays, composed entirely material. This process uses 2 µm-thick low-stress silicon nitride bottom insulator layer fGCFs. The effectiveness was validated scanning electron microscophy (SEM) energy dispersive X-ray spectroscopy (EDS) elemental analyses, confirmed uniformity Si₃N₄ insulation ensured overall integrity Using finite element analysis, optimized form factor achieve self-penetration up 3 mm into mouse striatum without additional support. characterization fGCFs high conductivity wide window. ability detect using fast scan cyclic voltammetry (FSCV) square wave (SWV), respectively, vitro vivo . With sensitivity detection, combined scalable self-supporting insertion capability, promising sensors offer enhanced practicality comprehensive monitoring.
Язык: Английский
Процитировано
0Electrocatalysis, Год журнала: 2025, Номер unknown
Опубликована: Март 25, 2025
Язык: Английский
Процитировано
0Microchemical Journal, Год журнала: 2025, Номер unknown, С. 113930 - 113930
Опубликована: Май 1, 2025
Язык: Английский
Процитировано
0