Macromolecular Rapid Communications, Год журнала: 2025, Номер unknown

Опубликована: Янв. 21, 2025

Abstract The increasing prevalence of antibiotic resistance, driven by the overuse and misuse conventional antibiotics, has become a critical public health concern. Photothermal antibacterial therapy (PTAT) utilizes heat generated photothermal agents under light exposure to inhibit bacterial growth without inducing attracting more attention. Quinoid conjugated polymers, especially para‐azaquinodimethane (AQM) polymer, are class organic semiconductors known for efficient π‐electron delocalization, near‐infrared absorption, narrow bandgap, showing great potential in application reagents. However, current AQM polymers face challenges related their solubility, photostability, biocompability. In this study, tetraglycol is introduced onto core improving drawbacks resulting polymers. Two with different electron donor (thiophene 2,2'‐bithiophene) synthesized evaluated various properties. PAQMT exhibited superior performance, including higher extinction coefficients, improved greater stability repeated NIR irradiation. further developed into nanoparticles via encapsulation, excellent colloidal stability, effective inhibition 808 nm light. This work provides new strategy properties offers opportunities promoting quinoidal PTAT.

Язык: Английский