Chromium Selectively Accumulates in the Rat Hippocampus after 90 Days of Exposure to Cr(VI) in Drinking Water and Induces Age- and Sex-Dependent Metal Dyshomeostasis DOI Creative Commons

Samuel T. Vielee,

William J. Buchanan,

Spencer H. Roof

и другие.

Toxics, Год журнала: 2024, Номер 12(10), С. 722 - 722

Опубликована: Окт. 3, 2024

Hexavalent chromium (Cr[VI]) is a widespread environmental pollutant in air and water that primarily attributed to industrial pollution. The current maximum contaminant levels (MCLs) for drinking from the World Health Organization U.S. Environmental Protection Agency (0.05 0.1 mg/L, respectively) were set based on contact dermatitis warrant further toxicological investigation. While Cr(VI) neurotoxic accumulates brain, most animal studies only report whole-brain Cr, leaving large knowledge gaps. Few consider differences between ages or sexes, fewer essential metal dyshomeostasis. We sought investigate where Cr considering sex age differences, following 90-day exposure MCLs. Here, we six brain regions of rats exposed Cr(VI). observed accumulated hippocampus, older females. assessed changes metals observing opposite effects across sexes young compared rats. In sum, our data indicate selectively targeted with geriatric females accumulating induced significant dyshomeostasis even tissues lacking evident accumulation.

Язык: Английский

Biochar enhances the simultaneous stabilization of chromium and lead in contaminated soil by Penicillium oxalicum SL2 DOI
Chun Zhang, Jing Wang, Haonan Zhang

и другие.

Chemical Engineering Journal, Год журнала: 2025, Номер 509, С. 161522 - 161522

Опубликована: Март 14, 2025

Язык: Английский

Процитировано

0
Advances in chromium removal using biomass‐derived activated carbon: A comprehensive review and bibliometric analysis DOI Open Access
Nicky Rahmana Putra, Muhammad Abbas Ahmad Zaini, Heri Septya Kusuma

и другие.

Environmental Progress & Sustainable Energy, Год журнала: 2025, Номер unknown

Опубликована: Март 28, 2025

Abstract This review presents a comprehensive analysis and bibliometric evaluation of chromium (Cr) removal from aqueous solutions using biomass‐derived activated carbon. A 250 publications 2000 to 2024 reveals increasing global research interest, with significant contributions China, India, the USA. Key themes identified include adsorption mechanisms, carbon modification, biosorption techniques. Biomass‐based adsorbents, such as corn cob, Ulva lactuca , Eichhornia crassipes demonstrate high capacities, ranging 80 mg/g for hexavalent (Cr(VI)), depending on preparation methods operational conditions. The highlights advanced techniques, including chemical activation KOH H₃PO₄, which enhance surface area up 1500 m 2 g −1 significantly improving performance. Despite promising results, challenges persist in scaling industrial applications, inconsistent performance across biomass types, need cost‐effective regeneration methods. Incorporating nanotechnology, metal oxide nanoparticles, has improved efficiencies by 30%, broadening potential applications. provides critical insights into optimizing methods, standardizing parameters, bridging gap between laboratory findings real‐world underscoring sustainable effective solution chromium‐contaminated wastewater treatment.

Язык: Английский

Процитировано

0
Current Understanding of Sex Differences in Metal-Induced Diseases DOI
Haiyan Lu, Morgan Delnicki, Gabrielle Griffin

и другие.

Current Environmental Health Reports, Год журнала: 2025, Номер 12(1)

Опубликована: Апрель 9, 2025

Язык: Английский

Процитировано

0
Female Rat Behavior Effects from Low Levels of Hexavalent Chromium (Cr[VI]) in Drinking Water Evaluated with a Toxic Aging Coin Approach DOI Creative Commons

Samuel T. Vielee,

Jessica Isibor,

William J. Buchanan

и другие.

Applied Sciences, Год журнала: 2024, Номер 14(14), С. 6206 - 6206

Опубликована: Июль 17, 2024

We are facing a critical aging crisis, with geriatric populations (65+) growing to unprecedented proportions and ~4 million people (a 6.5-fold increase) expected become centenarians by 2050. This is compounded environmental pollution, which affects individuals of all ages contributes age-related diseases. As we have limited understanding how pollutants affect older distinctly from younger populations, these longer-lived present key knowledge gap. To address this gap, employ “Toxic Aging Coin” approach: heads consider age impacts chemical toxicity, tails chemicals act as gerontogens—or they accelerate biological aging. employed approach investigate hexavalent chromium (Cr[VI]) on female rats exposed 0.05 or 0.1 mg Cr(VI)/L in drinking water for 90 days; the maximum contaminant levels (i.e., highest permitted) World Health Organization U.S. Environmental Protection Agency, respectively. During exposure, performed battery behavior assays assess grip strength, locomotor coordination, anxiety, spatial memory, sociability, social novelty preference. observed differences Cr(VI) neurotoxicity, function, memory middle-aged females being particularly affected. further compared results males, noting many sex differences, especially rats. These data emphasize need variables toxicology revisit regulations Cr(VI).

Язык: Английский

Процитировано

2
Chromium Selectively Accumulates in the Rat Hippocampus after 90 Days of Exposure to Cr(VI) in Drinking Water and Induces Age- and Sex-Dependent Metal Dyshomeostasis DOI Creative Commons

Samuel T. Vielee,

William J. Buchanan,

Spencer H. Roof

и другие.

Toxics, Год журнала: 2024, Номер 12(10), С. 722 - 722

Опубликована: Окт. 3, 2024

Hexavalent chromium (Cr[VI]) is a widespread environmental pollutant in air and water that primarily attributed to industrial pollution. The current maximum contaminant levels (MCLs) for drinking from the World Health Organization U.S. Environmental Protection Agency (0.05 0.1 mg/L, respectively) were set based on contact dermatitis warrant further toxicological investigation. While Cr(VI) neurotoxic accumulates brain, most animal studies only report whole-brain Cr, leaving large knowledge gaps. Few consider differences between ages or sexes, fewer essential metal dyshomeostasis. We sought investigate where Cr considering sex age differences, following 90-day exposure MCLs. Here, we six brain regions of rats exposed Cr(VI). observed accumulated hippocampus, older females. assessed changes metals observing opposite effects across sexes young compared rats. In sum, our data indicate selectively targeted with geriatric females accumulating induced significant dyshomeostasis even tissues lacking evident accumulation.

Язык: Английский

Процитировано

1