Advances and perspectives in fluorescent probes for imaging hepatopathy-related biomarkers

Coordination Chemistry Reviews, Год журнала: 2023, Номер 497, С. 215407 - 215407

Опубликована: Сен. 12, 2023

Язык: Английский

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Ex Tenebris Lux: Illuminating Reactive Oxygen and Nitrogen Species with Small Molecule Probes

Chemical Reviews, Год журнала: 2024, Номер 124(16), С. 9225 - 9375

Опубликована: Авг. 13, 2024

Reactive oxygen and nitrogen species are small reactive molecules derived from elements in the air─oxygen nitrogen. They produced biological systems to mediate fundamental aspects of cellular signaling but must be very tightly balanced prevent indiscriminate damage molecules. Small molecule probes can transmute specific nature each into an observable luminescent signal (or even acoustic wave) offer sensitive selective imaging living cells whole animals. This review focuses specifically on for superoxide, hydrogen peroxide, hypochlorite, nitric oxide, peroxynitrite that provide a or photoacoustic signal. Important background information general photophysical phenomena, common probe designs, mechanisms, modalities will provided, then, analyte thoroughly evaluated. A discussion successes field presented, followed by recommendations improvement future outlook emerging trends. Our objectives informative, useful, thorough guide as well important context compare ecosystem chemistries molecular scaffolds has manifested within field.

Язык: Английский

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A novel ultra-sensitive fluorescent probe for monitoring and imaging drug-induced/inhibited ferroptosis-mediated liver injury model via peroxynitrite fluctuations

Microchemical Journal, Год журнала: 2025, Номер unknown, С. 112833 - 112833

Опубликована: Янв. 1, 2025

Язык: Английский

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Emerging fluorescent probes for bioimaging of drug-induced liver injury biomarkers: Recent advances

Bioorganic Chemistry, Год журнала: 2025, Номер 159, С. 108407 - 108407

Опубликована: Март 24, 2025

Язык: Английский

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Dual-Channel Fluorescent Probe for Simultaneously Visualizing ONOO- and Viscosity in Epilepsy, Non-Alcoholic Fatty Liver and Tumoral Ferroptosis Models

Biosensors and Bioelectronics, Год журнала: 2025, Номер 282, С. 117495 - 117495

Опубликована: Апрель 17, 2025

Язык: Английский

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Screening and optimization of a water-soluble near-infrared fluorescent probe for drug-induced liver injury monitoring

Analytica Chimica Acta, Год журнала: 2023, Номер 1276, С. 341654 - 341654

Опубликована: Июль 24, 2023

Язык: Английский

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Harnessing polarity-dependent fluorescent probe for lipid droplet metabolism dissection and in vivo nonalcoholic fatty liver disease diagnosis

Sensors and Actuators B Chemical, Год журнала: 2023, Номер 399, С. 134825 - 134825

Опубликована: Окт. 20, 2023

Язык: Английский

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Molecular rotor bearing naphthol hydrazone Schiff base for sensing viscosity changes in solutions and biosystems

Dyes and Pigments, Год журнала: 2024, Номер 225, С. 112108 - 112108

Опубликована: Март 22, 2024

Язык: Английский

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In situ observation of mitochondrial viscosity in liver of mice with drug-induced liver injury by near-infrared fluorescence imaging

Talanta, Год журнала: 2024, Номер 284, С. 127229 - 127229

Опубликована: Ноя. 19, 2024

Язык: Английский

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Construction of a dual-excitation ratiometric fluorescent probe for determining peroxynitrite levels in living cells and zebrafish

Spectrochimica Acta Part A Molecular and Biomolecular Spectroscopy, Год журнала: 2024, Номер 313, С. 124084 - 124084

Опубликована: Фев. 29, 2024

Язык: Английский

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