Construction of a self-priming hairpin probe for rapid and isothermally one-step detection of multiple long noncoding RNAs in living cells and tissues
Chemical Engineering Journal,
Год журнала:
2025,
Номер
unknown, С. 159600 - 159600
Опубликована: Янв. 1, 2025
Язык: Английский
Exponential amplification reaction assisted CRISPR/Cas12a target-induced polarity switching photoelectrochemical biosensor for miRNA-622 detection
Sensors and Actuators B Chemical,
Год журнала:
2025,
Номер
unknown, С. 137723 - 137723
Опубликована: Март 1, 2025
Язык: Английский
Selective Naked-Eye Detection of Lung Squamous Cell Carcinoma Mediated by lncRNA SOX2OT Targeted Nanoplasmonic Probe
ACS Omega,
Год журнала:
2024,
Номер
9(35), С. 37205 - 37212
Опубликована: Авг. 21, 2024
The
application
of
nanobiotechnology
in
biomolecule
detection
can
provide
fast
and
accurate
tests
for
diagnosing
molecular
changing-associated
diseases.
use
AuNPs-thiolated
probe
conjugates
has
long
been
considered
as
an
alternative
method
the
specific
DNA/RNA
targets.
Here,
we
present
a
colorimetric
direct
SOX2OT
transcript,
noncoding
RNAs
(lncRNAs),
by
using
poly
guanine
tail
(G12)
template
situ
synthesis
gold
nanoparticles
(AuNPs)
without
any
chemical
modification
or
DNA
labeling.
We
have
then
developed
this
proposed
system
based
on
two
complementary
sequences
RNA
with
extra
strand
G12.
Using
method,
were
able
to
differentiate
lung
squamous
cell
carcinoma
from
adenocarcinoma
samples.
Based
disclosure,
invention
provides
simple
visual
detect
lncRNA
need
amplifying
target
discriminate
Our
diagnostic
kit
means
(PCR-free)
AuNPs
probes
Язык: Английский
Scientific investigation of non-coding RNAs in mitochondrial epigenetic and aging disorders: Current nanoengineered approaches for their therapeutic improvement
Mitochondrion,
Год журнала:
2024,
Номер
80, С. 101979 - 101979
Опубликована: Ноя. 5, 2024
Язык: Английский
An Anti-interference PEC-ECL Biosensing for Cancer-related Gene based on Self-supporting Semi-encapsulated Heterojunction Modulated Interface Polarity-Switching
Sensors and Actuators B Chemical,
Год журнала:
2024,
Номер
unknown, С. 136962 - 136962
Опубликована: Ноя. 1, 2024
Язык: Английский
Functionalizable poly-terthiophene/Cu2O heterojunction constructed in situ for sensitive photoelectrochemical detection of long non-coding RNA markers
RSC Advances,
Год журнала:
2024,
Номер
14(45), С. 32883 - 32892
Опубликована: Янв. 1, 2024
A
photoelectrochemical
(PEC)
sensor
based
on
the
poly-2,2,5,2-terthiophene
(pTTh)/Cu
2
O
heterojunction
was
constructed
and
applied
for
detection
of
long
non-coding
RNA
(lncRNA)
TROJAN,
a
biomarker
triple-negative
breast
cancer.
Язык: Английский