Phytochemical Analysis, Antioxidant, Anticholinergic, Antidiabetic, and Antiglaucoma Potentials of Sage (Salvia adiyamanensis)
Abstract
In
this
study,
the
antioxidant
effect
of
ethanolic
extracts
were
prepared
from
aerial
part
Salvia
adiyamanensis
was
investigated
through
five
methods,
including
DPPH⋅,
ABTS,
and
Fe3+,
Cu2+,
Fe3+-TPTZ
reducing
assays.
The
IC50
values
extract
determined
as
35.40
±
8.35
29.50
5.12
µg/mL
for
DPPH
ABTS
radicals
scavenging
enzyme
inhibition
property
against
α-glycosidase,
acetylcholinesterase,
butyrylcholinesterase,
human
carbonic
anhydrase
I,
II,
a
result,
IC50
30.78,
191.3,
8.02,
32.68
54.82
µg/mL,
respectively.
LC-MS/MS
revealed
that
S.
compromised
characteristic
phenolics
rosmarinic
acid,
chlorogenic
luteolin,
quercetin,
apigenin,
caffeic
acid
Salvia
genus.
These
findings
strongly
suggest
has
potential
to
be
natural
medicine
treatment
metabolic
diseases
such
diabetes,
Alzheimer’s
disease,
or
glaucoma.
Research Square (Research Square), Год журнала: 2025, Номер unknown
Опубликована: Апрель 10, 2025
Язык: Английский