Journal of The Electrochemical Society,
Год журнала:
2024,
Номер
171(11), С. 117523 - 117523
Опубликована: Ноя. 1, 2024
Cervical
cancer
remains
a
critical
women
health
issue,
predominantly
driven
by
high-risk
human
papillomavirus
(HPV)
types,
particularly
HPV
16
and
18.
Late-stage
diagnosis,
often
due
to
limited
diagnostic
tools
awareness,
exacerbates
the
problem,
especially
in
developing
countries.
Addressing
these
challenges,
our
study
introduces
an
electrochemical
sensor
for
detection
of
HPV18
L1
protein
first
time.
The
employs
gold
graphitic
carbon
nitride
(Au-g-C
3
N
4
)
nanocomposite
platform
with
monoclonal
antibodies
immobilised
via
drop-casting
method.
Detection
is
achieved
using
square
wave
voltammetry.
proposed
immunosensor
demonstrates
linear
range
(100
ag
ml
−1
1
ngml
low
limit
(35.16
),
exhibits
exceptional
sensitivity,
selectivity,
reproducibility,
stability.
Ultimately,
this
system
has
been
effectively
utilised
identification
various
positive
negative
undiluted
serum
samples
was
compared
ELISA
accuracy.
result
showed
that
promising
tool
reliable,
rapid,
accessible
L1,
potentially
enhancing
cervical
diagnostics
clinical
settings.
Molecules,
Год журнала:
2025,
Номер
30(3), С. 684 - 684
Опубликована: Фев. 4, 2025
The
fundamental
principle
of
Fourier
Transform
Infrared
(FTIR)
spectroscopy
is
based
on
the
vibration
and
rotation
atoms,
it
has
become
a
universal
widely
used
spectral
methodology
for
detection
internal
molecular
structures
in
diverse
range
fields.
A
considerable
number
review
articles
pertaining
to
applications
FTIR
have
been
published
recent
years.
Nevertheless,
comprehensive
summary
application
nanoparticles’
(NPs’)
green
synthesis
yet
be
presented.
In
present
paper,
we
propose
series
case
studies
that
demonstrate
analysis
metal
oxide
NPs
synthesized
using
processes.
Furthermore,
presented
position
functional
group
bands
spectra
are
responsible
reduction,
capping
stabilization
NPs.
this
review,
explore
advantages
limitations
methodologies
overcoming
these
challenges.
We
also
potential
solutions
complex
spectra.
intended
serve
as
compendium
information
researchers
engaged
field
NPs,
utilizing
research
tool.
Nanoscale Advances,
Год журнала:
2024,
Номер
unknown
Опубликована: Янв. 1, 2024
A
family
of
2D
monolayers
gold
nanoparticles
exhibits
unique
physicochemical
properties.
This
review
explores
their
formation,
assembly,
key
interactions,
applications,
challenges,
and
future
prospects.
Scientific Reports,
Год журнала:
2025,
Номер
15(1)
Опубликована: Март 12, 2025
Terahertz
spectroscopy
has
drawn
great
interest
for
the
detection
and
characterization
of
biological
matter,
but
its
limited
sensitivity
to
biomolecules
with
weak
changes
in
dielectric
properties
varying
concentration
hinders
potential
bio-sensing
applications.
Here,
a
novel
terahertz
sensor
was
developed
enhancing
ability
detect
based
on
two
electromagnetically
induced
transparency
(EIT)
metamaterials
coupled
gold
nanoparticles
(AuNPs)
integrated
biomolecules.
The
electrostatic
interaction
between
AuNPs
positively
charged
generates
localized
field
enhancement
at
biomolecule–metamaterial
interface,
resulting
threefold
increase
histidine
that
exhibit
property
concentration.
As
contrast,
glucose
shows
weaker
effect
due
electrostatically
neutral
nature.
Experimental
studies
reveal
by
evaluating
modulation
depth
(MD)
(ME)
factors
transmission
peak
presence
AuNPs,
we
achieve
enhance
intuitive
discrimination
these
Additionally,
two-EIT
metamaterial
1
×
2
pixel
array
enables
multiparameter
imaging,
visualizing
spatial
distribution
Our
results
not
only
significantly
improve
response
domain,
also
provide
new
idea
developing
high-sensitivity
functionalized
biosensors
advancing
multi-biomolecular
analysis
imaging
techniques.
Therapeutic Delivery,
Год журнала:
2025,
Номер
unknown, С. 1 - 11
Опубликована: Март 20, 2025
Aim
This
study
focuses
on
the
synthesis
and
evaluation
of
innovative
gold
nanoparticles
(AuNps)
stabilized
by
short-chain
ferulic
acid
(FA),
specifically
4-hydroxy-3-methoxy-cinnamic
acid.
ACS Measurement Science Au,
Год журнала:
2025,
Номер
5(1), С. 96 - 108
Опубликована: Янв. 23, 2025
Sometimes,
smaller
size
is
not
always
better,
and
looking
for
nanomaterials
that
offer
better
device
performance
requires
consideration
of
their
properties
at
the
first
stage.
In
this
study,
effects
polyethylenimine-capped
AuNPs
(PEI-AuNPs)
proteins
on
immunosensor
performances,
namely,
sensitivity
limit
detection,
are
examined.
The
size-effect
investigation
PEI-AuNPs
involves
modification
surface
disposable
screen-printed
carbon
electrodes
to
support
primary
antibodies
ability
load
secondary
redox
probes
perform
amplification
in
immunosensor.
correlation
average
size,
electrochemical
activities,
protein
property
investigated.
synthesized
with
different
diameters
ranging
from
4.7
44.9
nm
employed
investigation.
When
sensor
forms
a
sandwich
architecture,
detection
employs
current
response
Ag+
ions
bioconjugate,
which
greatly
increases
by
increasing
concentration.
addition,
best
signal
or
antibody
complexes
unique
AuNPs'
allows
superior
amplification.
effect
using
sizes
target
devices
significantly
observed.
Although
general
small-sized
high
active
areas,
can
improve
electrode
surface,
reactivity,
performance,
we
observe
medium
(16.3
nm)
gives
type.
Therefore,
finding
useful
considering
optimizing
tunable
voltammetric
acquiring
sensor.
