ChemInform, Год журнала: 2014, Номер 45(47)
Опубликована: Ноя. 6, 2014
Abstract γ‐Nitro‐substituted carbonyl compounds undergo a selenium catalyzed reductive cyclization with CO as reducing agent to yield multi‐ fully‐substituted pyrroles (II) and (IV).
Язык: Английский
Catalysis Science & Technology, Год журнала: 2019, Номер 9(5), С. 1073 - 1091
Опубликована: Янв. 1, 2019
Organoselenium chemistry has become an important tool in synthetic and medicinal chemistry.
Язык: Английский
Процитировано
171
Organic Letters, Год журнала: 2015, Номер 17(3), С. 488 - 491
Опубликована: Янв. 16, 2015
Microwave-promoted iminyl radical cyclizations can be terminated by trapping with TEMPO, affording functionalized adducts. The use of alkynes as acceptors delivers a range 2-acylpyrroles in good yields. Toxic and hazardous reagents, which are frequently employed reactions, not required. O-phenyl oxime ether substrates constructed single step from readily available ketones.
Язык: Английский
Процитировано
73
Tetrahedron, Год журнала: 2022, Номер 112, С. 132752 - 132752
Опубликована: Март 31, 2022
Язык: Английский
Процитировано
33
Organic Letters, Год журнала: 2014, Номер 17(2), С. 173 - 175
Опубликована: Дек. 31, 2014
A ruthenium-catalyzed reductive amination without an external hydrogen source has been developed using carbon monoxide as the reductant and ruthenium(III) chloride (0.008–2 mol %) catalyst. The method was applied to synthesis of antianxiety agent ladasten.
Язык: Английский
Процитировано
55
Current Organic Synthesis, Год журнала: 2022, Номер 19(3), С. 393 - 413
Опубликована: Фев. 11, 2022
Abstract: : Organoselenium chemistry has developed as an important tool in the field of synthetic and medicinal chemistry. Various organoselenium reagents have been used successfully to achieve different organic transformations such selenocyclizations, oxyselenenylations selenoxide eliminations etc. Additionally, potential is not limited their use stoichiometric but they organocatalyst number transformations. inorganic oxidants identified terminal regenerate active catalytic specie. In this review article, recent progress catalysis being highlighted along with asymmetric variants.
Язык: Английский
Процитировано
23
Russian Chemical Bulletin, Год журнала: 2025, Номер 74(2), С. 305 - 327
Опубликована: Фев. 1, 2025
Язык: Английский
Процитировано
0
Current Organic Chemistry, Год журнала: 2020, Номер 24(11), С. 1196 - 1229
Опубликована: Май 28, 2020
Pyrroles are the most prevalent heterocyclic compounds, which present as basic cores in many natural products, such vitamin B12, bile pigments like bilirubin and biliverdin, porphyrins of heme, chlorophyll, chlorins, bacteriochlorins, porphyrinogens. The biological activities compounds having pyrrole analogs include antimicrobial (antibacterial, antifungal), anti-cancer (anti-cytotoxic, antimitotic), anti-tumor, anti-hyperlipidemic, anti-depressant, anti-inflammatory, antihyperglycemic, antiproliferative, anti-HIV anti-viral activities. Accordingly, significant attention has been paid to develop competent methods for synthesis pyrroles with improved yields short times. This review gives an overview different using easily available precursors following routes. Synthesis monosubstituted 2,5-dimethoxyfuran dialkylacetylene dicarboxylate β-ketoester 1,2-dicarbonyl 1,3-dicarbonyl 1,3-dicarbonyl, amine, nitro aldehyde group 1,4-dicarbonyl compound amines enones moieties acetylene
Язык: Английский
Процитировано
24
The Chemical Record, Год журнала: 2024, Номер unknown
Опубликована: Ноя. 22, 2024
Abstract The conversion of a functional group into another represents the core organic synthesis. Within arena interconversions, oxidative and reductive transformations occupy privileged position development new sustainable, selective, general methodologies continue to attract significant interest. Owing versatility their chemistry, selenium compounds offer opportunities achieve both oxidation reduction wide range groups. Additionally, possibility generate in situ active oxidant or reducing species from suitable inert precursors enables catalytic processes. In this review, recent advances selenium‐mediated with particular emphasis on cutting‐edge researches bringing about insights comprehension mechanistic aspects, will be discussed.
Язык: Английский
Процитировано
2
Organic & Biomolecular Chemistry, Год журнала: 2016, Номер 14(14), С. 3603 - 3607
Опубликована: Янв. 1, 2016
This paper presents efficient access to chiral hydroxyimino tetrahydrobenzofuranones featuring a trifluoromethyl group at an all-carbon quaternary stereocenter.
Язык: Английский
Процитировано
15
Industrial & Engineering Chemistry Research, Год журнала: 2017, Номер 56(8), С. 1895 - 1902
Опубликована: Фев. 3, 2017
Regenerable flue gas desulfurization (FGD) is highly attractive because of the transformation sulfur dioxide (SO2) to high-value products. In this study, selenium-assisted SO2 reduction by carbon monoxide (CO) in liquid phase [dimethylformamide (DMF) + water (H2O) mixture] proposed and applied FGD process. This process realizes recycle elemental product under room temperature. Moreover, results show that both selenium catalyst DMF solvent have good stability can be well recycled, implying economically feasible. Furthermore, mechanism CO DMF/H2O investigated. Results dissolves solution forms Sen2– species, which are active intermediates promote formation product.
Язык: Английский
Процитировано
10