We
have
developed
Cp*Co(III)-catalyzed
reverse
regioselective
[4+2]
annulation
of
N-chlorobenzamides/acrylamides
with
vinyl
silanes
for
the
synthesis
4-silylated
isoquinolones.
The
reaction
was
performed
at
ambient
temperature
under
redox-neutral
conditions.
utilizes
N-Cl
bond
as
an
internal
oxidant
and
furnished
required
products
excellent
regioselectivities
demonstrated
high
functional
group
tolerance.
Moreover,
isoquinolone
derivatives
were
readily
converted
into
3,4-dihydroisoquinolones
via
protodesilylation
thus
making
silane
ethylene
surrogate.
Green Synthesis and Catalysis,
Год журнала:
2024,
Номер
5(4), С. 211 - 269
Опубликована: Май 6, 2024
The
development
of
catalytic
carbonylation
reactions
has
increased
considerably.
Although
many
reviews/chapters/books
on
have
been
published,
summaries
cheap
metal-catalyzed
aryl
halides
and
other
chemical
bonds
with
high
dissociation
energy
C-Y
(Y
=
O,
N,
H)
are
still
very
rare.
Focusing
green
sustainable
chemistry,
this
review
summarizes
discusses
the
achievements
carbonylative
transformations
(C(sp2)-X)
strong
based
non-expensive
metal
catalysts
(Co,
Mn,
Mo,
Ni,
Fe,
Cu),
photochemical
electrochemical
systems
developed
in
recent
decades.
Organic & Biomolecular Chemistry,
Год журнала:
2023,
Номер
21(19), С. 3918 - 3941
Опубликована: Янв. 1, 2023
This
review
demonstrates
the
redox-neutral
synthetic
approaches
towards
valuable
heterocycles
such
as
isoquinolines,
indoles,
isoquinolones,
and
tetrahydroquinolines
via
high-valent
Cp*Co(
iii
)
catalysis.
Synthesis,
Год журнала:
2022,
Номер
55(05), С. 846 - 856
Опубликована: Окт. 12, 2022
Abstract
A
novel
and
efficient
method
has
been
developed
for
the
direct
synthesis
of
substituted
imidazoles
through
reaction
styrenes
benzylamines
with
assistance
I2-DMSO
concerted
system.
The
reactions
proceed
efficiently
under
open
air
solvent-free
conditions
to
afford
a
wide
variety
in
good
yields.
productive
large-scale
also
performed
target
highly
heterocyclic
motifs.
present
protocol
offers
metal-
process,
mild
conditions,
easily
accessible
reactants,
operational
simplicity
achieve
an
assembly
N-heterocyclic
compounds.
Chemistry - An Asian Journal,
Год журнала:
2023,
Номер
19(1)
Опубликована: Дек. 5, 2023
Abstract
Iron‐catalyzed
C−H
activation
has
recently
emerged
as
an
increasingly
powerful
synthetic
method
for
the
step‐
and
atom‐
economical
direct
functionalizations
of
otherwise
inert
bonds.
Iron's
low‐cost
toxicity
along
with
its
catalytic
versatility
have
encouraged
scientific
community
to
elect
this
metal
development
new
methodologies.
Within
review,
we
aim
present
a
collection
most
recent
examples
iron‐catalyzed
particular
emphasis
on
modern
strategies
mechanistic
aspects.
Asian Journal of Organic Chemistry,
Год журнала:
2025,
Номер
unknown
Опубликована: Май 26, 2025
Abstract
Photo‐assisted,
iron‐catalyzed
C─H
functionalizations
represent
nowadays
a
sustainable
tool
to
develop
unprecedented
transformations,
unviable
by
common
catalytic
organometallic
approaches
promoted
transition
metals.
In
fact,
the
use
of
this
new
technology
allows
for
more
efficient
synthetic
transformations
increasing
chemo‐,
regio‐
and
site‐selectivity
catalysis
while
reducing
formation
by‐products
shortening
reaction
times.
Further,
replacement
precious
transition‐metals
with
iron
catalysts
is
highly
desiderable
development
environmentally‐friendly
methods.
Within
review,
we
aim
summarize
latest
achievements
combining
most
abundant
safe
metal
in
“outer‐sphere”
functionalization
reactions
mediated
light
C─C
C─Het
bonds,
including
challenging
C─N,
C─P,
C─B
C─S
bonds.
Particular
attention
has
been
directed
toward
description
mechanistic
aspects
application
methods
late‐stage
polymers,
marketed
drugs,
biologically‐active
compounds
materials.
ACS Omega,
Год журнала:
2023,
Номер
8(28), С. 25262 - 25271
Опубликована: Июль 5, 2023
We
have
developed
Cp*Co(III)-catalyzed
redox-neutral
synthesis
of
3,4-unsubstituted
isoquinoline
1(2H)-ones
at
ambient
temperature
using
N-chloroamides
as
a
starting
material.
The
reaction
utilizes
vinyl
acetate
an
inexpensive
and
benign
acetylene
surrogate.
N-Cl
bond
the
N-chlorobenzamides
plays
role
internal
oxidant
hence
precludes
need
for
external
oxidant.
works
with
wide
range
substrates
having
various
functional
groups
substrate
containing
heterocyclic
ring.
Notably,
is
extended
to
N-chloroacrylamides
in
which
vinylic
C-H
activation
occurs
furnish
2-pyridone
derivatives.
Preliminary
mechanistic
studies
were
also
conducted
shed
light
on
mechanism
this
reaction.
Organic & Biomolecular Chemistry,
Год журнала:
2024,
Номер
22(22), С. 4528 - 4535
Опубликована: Янв. 1, 2024
Phosphine-free,
air
stable
cobalt(
ii
)
based
complexes
consisting
of
imino
phenol
ligands
were
synthesized
and
utilized
as
catalysts
in
the
coupling
reaction
alcohols
with
amines
into
imines
following
an
acceptorless
dehydrogenative
pathway.
