Advancement of vinylene carbonate as a coupling partner in metal-catalyzed C–H functionalization

Organic Chemistry Frontiers, Год журнала: 2023, Номер 10(22), С. 5717 - 5734

Опубликована: Янв. 1, 2023

Vinylene carbonate (VC) has emerged as a promising coupling partner to participate in various attractive C–H conversions and implement an increasing number of novel reactions. In this review, we provide summary the advancements achieved metal-catalyzed functionalization using VC.

Язык: Английский

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Chemical upcycling of poly(bisphenol A carbonate) to vinylene carbonates through organocatalysis

Green Chemistry, Год журнала: 2023, Номер 25(11), С. 4282 - 4291

Опубликована: Янв. 1, 2023

The chemical upcycling of poly(bisphenol A carbonate) was carried out through organocatalysis using α-hydroxyketones as nucleophiles, leading to valuable vinylene carbonates.

Язык: Английский

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Rhodium(III)‐Catalyzed C−H/N−H Activation for Direct Synthesis of Pyrimidoindolones under Mild Conditions

Chemistry - An Asian Journal, Год журнала: 2023, Номер 18(19)

Опубликована: Авг. 24, 2023

Pyrimidoindolones are an important structural motif found in many natural products and essential to the pharmaceutical agrochemical industry. Direct synthesis of 3,4-unsubstituted pyrimidoindolones is not easily accessible. Here we report a rhodium(III)-catalyzed C-H/N-H activation annulation approach for obtaining from N-carbamoylindoles vinylene carbonate. The reaction occurs at room temperature does require any external oxidants. A diverse spectrum indoles were demonstrated be viable substrates capable producing desired high yields. In addition, scope has been expanded include pyrrole substrate. Furthermore, detailed mechanistic studies have performed delineate working mode reaction.

Язык: Английский

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Recent Progress in C—H Bond Activation Reaction with Vinylene Carbonate

Chinese Journal of Organic Chemistry, Год журнала: 2023, Номер 43(9), С. 3119 - 3119

Опубликована: Янв. 1, 2023

Язык: Английский

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Recent Progress in Transition Metal-Catalyzed C—H Bond Activation of N-Aryl Phthalazinones

Chinese Journal of Organic Chemistry, Год журнала: 2022, Номер 42(9), С. 2682 - 2682

Опубликована: Янв. 1, 2022

Язык: Английский

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Ruthenium-Catalyzed C—H [4＋2] Annulation of Quinazolinones with Vinylene Carbonate

Chinese Journal of Organic Chemistry, Год журнала: 2023, Номер 43(4), С. 1537 - 1537

Опубликована: Янв. 1, 2023

Transition metal-catalyzed inert C-H annulation reaction, an efficient strategy in the field of organic chemistry, is capable constructing a series carbon-or heterocycle molecules.Very recently, chemists have commenced to employ vinylene carbonate as carbon synthon for construction non-substituted heterocyclic compounds, which benefits with enriched product structure, quite simple and concise reaction system, sole carbonic acid by-product.A new type [4＋2] cyclization quinazolinone ethylene catalyzed by ruthenium proposed, 2,3-fused derivatives are obtained good yields.

Язык: Английский

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Rhodium-catalyzed C–H carboxymethylation of anilines with vinylene carbonate

Organic & Biomolecular Chemistry, Год журнала: 2023, Номер 21(41), С. 8320 - 8328

Опубликована: Янв. 1, 2023

A rhodium-catalyzed synthesis of phenylacetate has been realized by direct C-H carboxymethylation anilines bearing removable directing groups. The reaction occurred most efficiently in air, without any external base or oxidant. This methodology is expected to provide a facile and general access various bioactive 2-amino aromatic acetic acid derivatives.

Язык: Английский

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Rh(III)-Catalyzed C(7)—H Formylmethylation of Indoline with Vinylene Carbonate

Chinese Journal of Organic Chemistry, Год журнала: 2023, Номер 43(8), С. 2905 - 2905

Опубликована: Янв. 1, 2023

A Rh(III)-catalyzed synthesis of arylacetaldehydes via C-H formylmethylation with vinylene carbonate has been developed.The reaction proceeded smoothly to give C7-functionalized N-(2-pyrimidyl)-indolines in moderate good yields.This protocol features simple system, excellent regioselectivity, and functional group compatibility.

Язык: Английский

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Vinylene Carbonate: A Versatile Synthon in Organic Synthetic Chemistry

Chinese Journal of Organic Chemistry, Год журнала: 2024, Номер 44(7), С. 2147 - 2147

Опубликована: Янв. 1, 2024

Язык: Английский

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