Plasma,
Год журнала:
2024,
Номер
7(1), С. 233 - 257
Опубликована: Март 16, 2024
Plasma
medicine
is
an
emerging
field
that
applies
the
science
and
engineering
of
physical
plasma
to
biomedical
applications.
Low-temperature
plasma,
also
known
as
cold
generated
via
ionization
atoms
in
a
gas,
generally
exposure
strong
electric
fields,
consists
ions,
free
radicals,
molecules
at
varying
energy
states.
Plasmas
low
temperatures
(approximately
room
temperature)
have
been
used
for
applications
dermatology,
oncology,
anti-microbial
strategies.
Despite
current
ongoing
clinical
use,
exact
mechanisms
action
full
range
effects
treatment
on
cells
are
only
just
beginning
be
understood.
Direct
indirect
immune
potential
utilized
various
such
immunomodulation,
anti-infective
therapies,
regulating
inflammation.
In
this
review,
we
combine
diverse
expertise
fields
chemistry,
device
design,
immunobiology
cover
history
state
medicine,
basic
chemistry
their
implications,
atmospheric
host
with
immunological
consequences,
future
directions,
outlook
recommendations
medicine.
Applied Sciences,
Год журнала:
2021,
Номер
11(11), С. 4809 - 4809
Опубликована: Май 24, 2021
In
recent
years,
cold
atmospheric
pressure
plasma
(CAPP)
technology
has
received
substantial
attention
due
to
its
valuable
properties
including
operational
simplicity,
low
running
cost,
and
environmental
friendliness.
Several
different
gases
(air,
nitrogen,
helium,
argon)
techniques
(corona
discharge,
dielectric
barrier
jet)
can
be
used
generate
at
temperature.
Plasma
treatment
is
routinely
in
materials
science
modify
the
surface
(e.g.,
wettability,
chemical
composition,
adhesion)
of
a
wide
range
polymers,
textiles,
metals,
glasses).
Moreover,
CAPP
seems
powerful
tool
for
inactivation
various
pathogens
bacteria,
fungi,
viruses)
food
industry
packing
material
decontamination,
shelf
life
extension),
agriculture
disinfection
seeds,
fertilizer,
water,
soil)
medicine
sterilization
medical
equipment,
implants).
also
holds
great
promise
direct
therapeutic
treatments
dentistry
(tooth
bleaching),
dermatology
(atopic
eczema,
wound
healing)
oncology
(melanoma,
glioblastoma).
Overall,
an
innovative,
effective
offering
broad
application
potential.
However,
limitations
negative
impacts
need
determined
order
receive
regulatory
approval
consumer
acceptance.
Plasma Sources Science and Technology,
Год журнала:
2022,
Номер
31(5), С. 054002 - 054002
Опубликована: Март 23, 2022
Abstract
Plasma
medicine
refers
to
the
application
of
nonequilibrium
plasmas
at
approximately
body
temperature,
for
therapeutic
purposes.
Nonequilibrium
are
weakly
ionized
gases
which
contain
charged
and
neutral
species
electric
fields,
emit
radiation,
particularly
in
visible
ultraviolet
range.
Medically-relevant
cold
atmospheric
pressure
plasma
(CAP)
sources
devices
usually
dielectric
barrier
discharges
jets.
diagnostic
methods
modelling
approaches
used
characterize
densities
fluxes
active
their
interaction
with
surrounding
matter.
In
addition
direct
onto
living
tissue,
treatment
liquids
like
water
or
physiological
saline
by
a
CAP
source
is
performed
order
study
specific
biological
activities.
A
basic
understanding
between
bio-interfaces
essential
follow
effects.
Charged
species,
metastable
other
atomic
molecular
reactive
first
produced
main
ignition
transported
discharge
afterglow
finally
be
exposed
targets.
Contact
these
liquid-dominated
generates
secondary
oxygen
nitrogen
(ROS,
RNS).
Both
ROS
RNS
possess
strong
oxidative
properties
can
trigger
redox-related
signalling
pathways
cells
leading
various
impacts
relevance.
Dependent
on
intensity
exposure,
redox
balance
influenced
way
that
eustress
leads
stimulation
cellular
processes
distress
cell
death.
Currently,
clinical
realized
mainly
wound
healing.
The
use
cancer
(i.e.
oncology)
currently
emerging
field
research.
Future
perspectives
challenges
directed
towards
control
optimization
devices,
broaden
establish
its
medical
applications,
open
up
new
plasma-based
therapies
medicine.
ACS Applied Bio Materials,
Год журнала:
2022,
Номер
5(5), С. 2046 - 2068
Опубликована: Апрель 27, 2022
Recent
advances
in
microfluidics-based
point-of-care
testing
(POCT)
technology
such
as
paper,
array,
and
beads
have
shown
promising
results
for
diagnosing
various
infectious
diseases.
The
fast
timely
detection
of
viral
infection
has
proven
to
be
a
critical
step
deciding
the
therapeutic
outcome
current
COVID-19
pandemic,
which
turn
not
only
enhances
patient
survival
rate
but
also
reduces
disease-associated
comorbidities.
In
present
scenario,
rapid,
noninvasive
virus
using
low
cost
high
throughput
POCT
devices
embraces
advantages
over
existing
diagnostic
technologies,
centralized
lab
facility,
expensive
instruments,
sample
pretreatment,
skilled
personnel
are
required.
Microfluidic-based
multiplexed
can
boon
clinical
diagnosis
developing
countries
that
lacks
health
care
system
resources.
microfluidic
used
disease
exploited
development
drug
efficacy
treatment
model
systems.
havoc
created
by
second
wave
led
several
countries'
governments
back
front.
lack
kits,
medical
devices,
human
resources
huge
demand
remotely
operated
with
single
touch
data
analyzed
on
phone.
advancements
information
use
smartphones
paradigm
shift
explored
deal
pandemic
situation.
This
review
sheds
light
approaches
cost-effective
microfluidics
devices.
successfully
under
settings
along
their
pros
cons
been
discussed
here.
Further,
integration
wireless
network
systems
Internet-of-things
will
enable
readers
manufacturing
advanced
remote
management
resource
settings.
Journal of Advanced Research,
Год журнала:
2022,
Номер
43, С. 59 - 71
Опубликована: Март 9, 2022
Outbreaks
of
airborne
viral
infections,
such
as
COVID-19,
can
cause
panic
regarding
other
severe
respiratory
syndrome
diseases
that
may
develop
and
affect
public
health.
It
is
therefore
necessary
to
control
methods
offer
protection
against
viruses.To
identify
a
feasible
solution
for
virus
deactivation,
we
critically
reviewed
generating
reactive
oxygen
species
(ROS),
which
attack
wide
range
molecular
targets
induce
antiviral
activity,
accounting
their
flexibility
in
facilitating
host
defense
mechanisms
comprehensive
pathogens.
Recently,
the
role
ROS
microbial
decontamination
has
been
investigated
major
topic
infectious
diseases.
eradicate
pathogens
directly
by
inducing
oxidative
stress
or
indirectly
promoting
pathogen
removal
through
numerous
non-oxidative
mechanisms,
including
autophagy,
T-cell
responses,
pattern
recognition
receptor
signaling.In
this
article,
possible
vitro
generation
with
activity.
Furthermore,
discuss,
detail,
novel
environmentally
friendly
cold
plasma
delivery
system
destruction
viruses.
This
review
highlights
potential
therapeutic
mediators
modernize
current
techniques
improvement
on
efficiency
inactivating
SARS-CoV2
Catalysts,
Год журнала:
2023,
Номер
13(4), С. 685 - 685
Опубликована: Март 31, 2023
Recent
advances
in
atmospheric
plasmas
have
led
to
the
formation
of
nonthermal
plasma
(NTP).
In
recent
decades,
a
number
novel
diagnostic
approaches
been
implemented
and
reported
order
better
understand
physics
NTP.
The
use
NTP
is
approach
producing
reactive
oxygen
nitrogen
species.
Plasma
technology
has
many
applications,
including
electrical
device
microfabrication,
biomedicine,
dentistry,
agriculture,
ozone
generation,
chemical
synthesis,
surface
treatment,
coating,
disease
therapy.
Furthermore,
thought
be
successful
strategy
for
degradation
hazardous
pollutants
environment,
making
it
future
hope.
studies
showed
that
various
operating
parameters
affect
yield
NTP-based
technology.
Especially,
presence
catalyst,
properly
placed
an
reactor,
leads
significant
increase
process
performance
as
compared
alone.
Scientists
looked
at
using
conjunction
with
catalysts
remove
sorts
from
environment.
this
context,
review
articles
are
crucial
due
prevalence
applications
ongoing
developments.
This
will
describe
advancements
biomedical
bacterial
inactivation,
food
preservation
storage,
environmental
catalytic
formulations.
could
useful
providing
platform
biological
protection
through
Microorganisms,
Год журнала:
2021,
Номер
9(2), С. 232 - 232
Опубликована: Янв. 22, 2021
Recently,
the
outbreak
of
coronavirus
disease
2019
(COVID-19),
caused
by
SARS-CoV-2
virus,
in
China
and
its
subsequent
spread
across
world
has
numerous
infections
deaths
disrupted
normal
social
activity.
Presently,
various
techniques
are
used
for
diagnosis
infection,
with
advantages
weaknesses
to
each.
In
this
paper,
we
summarize
promising
methods,
such
as
reverse
transcription-polymerase
chain
reaction
(RT-PCR),
serological
testing,
point-of-care
smartphone
surveillance
infectious
diseases,
nanotechnology-based
approaches,
biosensors,
amplicon-based
metagenomic
sequencing,
smartphone,
wastewater-based
epidemiology
(WBE)
that
can
also
be
utilized
detection
SARS-CoV-2.
addition,
discuss
principles,
advantages,
disadvantages
these
highlight
potential
methods
development
additional
products
early
fast
