
bioRxiv (Cold Spring Harbor Laboratory), Год журнала: 2025, Номер unknown
Опубликована: Фев. 18, 2025
Abstract The human auditory system must distinguish relevant sounds from noise. Severe hearing loss can be treated with cochlear implants (CIs), but how the brain adapts to electrical remains unclear. This study examined adaptation unilateral CI use in first and seventh month after CI-activation using speech comprehension measures EEG recordings, both during passive listening an active spatial task. We here provide electrophysiological evidence for a longitudinal increase temporal coding acuity decrease cortical overrepresentation of acoustic input six months following activation CI. Specifically, neural phase-locking 40-Hz amplitude-modulated (AM) increased, while 4-Hz AM decreased, indicating refined processing reduced overrepresentation, respectively. In task, benefit was most pronounced when ear primarily exposed target speech. Lateralized alpha oscillations (∼10 Hz) reliably marked users’ focus attention. Stronger modulation hemisphere opposite non-implanted indicates attentional bias toward acoustically ear. Our findings suggest that is accomplished by dynamic improvements persistent
Язык: Английский