Abstract
A
novel
phthalocyanine‐based
hybrid
nanofilm
is
for
the
first
time
successfully
applied
as
an
oxidative
platform
surface
enhanced
Raman
spectroscopy
(SERS)
sensing
to
fine‐resolve
Raman‐inactive
compounds.
The
formed
by
self‐assembly
of
zinc(II)
2,3,9,10,16,17,23,24‐Octa[(3′,5′‐dicarboxy)‐phenoxy]phthalocyaninate
(ZnPc*)
with
solid‐supported
monolayer
graphene
oxide
(GO)
mediated
zinc
acetate
metal
cluster.
Atomic
force
microscopy,
UV–vis
and
fluorescence
spectroscopies
confirm
that
this
simple
coordination
motive
in
combination
molecular
structure
ZnPc*
prevents
contact
quenching
light‐excited
triplet
state
through
aromatic
stacking
GO
particles.
Fluorescence
probing
Sensor
Green
terephthalic
acid
specific
indicators
active
oxygen
intermediates
shows
initiates
selective
singlet
generation
under
visible
light.
Direct
one‐electron
oxidation
tetramethylbenzidine
(TMB)
(1.0×10
−7
m
)
on
presence
100
nm
silver
nanoparticles
plasmonic
hot‐spots
450–640‐nm
light
irradiation
yields
well‐resolved
resonance
spectrum
oxidized
form
TMB
+1
.
Using
these
nanofilms
platforms
redox
reaction
target
analytes
without
additional
oxidizing
agents,
range
Raman‐detectable
compounds
can
be
significantly
expanded
a
rapid
ultrasensitive
SERS
screening
substances
currently
considered
Raman‐inactive.
In
this
study,
a
Pd
nanoparticles@hydrogen-bonded
organic
framework
(Pd
NPs@HOF)
thin
film
was
fabricated
at
the
toluene-water
interface.
The
HOF
formed
through
interaction
of
trimesic
acid
(TMA)
and
melamine
(Mel)
in
water
phase,
while
Pd(0)
produced
from
reduction
[PdCl2(cod)]
phase.
as-synthesized
NPs@HOF
demonstrated
to
be
an
effective
catalyst
for
selective
p-nitrophenol
o-nitrophenol
p-aminophenol
o-aminophenol.
porous
network
introduced
strong
active
sites
between
Mel,
TMA,
Pd(0).
Kinetic
studies
showed
that
exhibited
enhanced
rate
comparison
with
Pd@reduced-graphene
oxide
(r-GO)
rates
were
1.7
times
faster
1.5
or
even
10
than
some
Pd-based
catalysts,
maximum
conversion
97.1%
which
attributed
higher
porosity
greater
surface-to-volume
ratio
material.
Furthermore,
π-π
stacking
interactions
enhance
catalytic
activity
by
increasing
sites,
stabilizing
NPs
trapping
nitrophenols,
facilitating
electron
transfer,
providing
synergistic
effect.
Also,
contributions
hydrogen
bonding,
van
der
Waals
forces,
electrostatic
interactions,
π-σ
noncovalent
are
reasons
better
performance
Pd/r-GO
reduced
functional
groups.
ACS Applied Materials & Interfaces,
Год журнала:
2025,
Номер
unknown
Опубликована: Март 2, 2025
The
detection
and
quantification
of
veterinary
drug
residues
in
meat
remain
a
significant
challenge
due
to
the
complex
background
interference
inherent
matrix,
which
compromises
stability
accuracy
spectroscopic
analysis.
This
study
introduces
an
advanced
label-free
surface-enhanced
Raman
spectroscopy
(SERS)
platform
for
precise
identification
drugs.
By
employing
dual
enhancement
strategy
involving
sodium
borohydride
activation
calcium
ion-deuterium
oxide
guidance,
this
achieves
efficient
capture
signal
amplification
molecules
on
highly
active
nanoparticles.
High-quality
SERS
spectra
were
obtained
carprofen,
doxycycline
hydrochloride,
chloramphenicol,
penicillin
G
salt,
enabling
accurate
classification
suppression.
In
addition,
application
machine
learning
algorithms,
including
PCA-LDA,
heatmap,
decision
tree
modeling,
allows
differentiation
mixed
samples.
Quantitative
analyses
samples
achieved
through
intensity
ratios
multivariate
curve
resolution-alternate
least-squares
(MCR-ALS)
analysis,
with
results
showing
high
consistency
high-performance
liquid
chromatography
(HPLC)
measurements.
These
findings
highlight
potential
SERS-based
rapid
multicomponent
food
matrices.
Laser & Photonics Review,
Год журнала:
2025,
Номер
unknown
Опубликована: Апрель 13, 2025
Abstract
Surface‐enhanced
Raman
scattering
(SERS)
demonstrates
remarkable
sensitivity
and
specificity
in
biosensing
applications.
However,
attempts
to
improve
SERS
performance
by
fabricating
metal
nanostructures
with
sharper
hotspot
structures
have
encountered
bottleneck,
as
the
extremely
short
effective
distance
remains
unresolved.
Here,
a
strategy
modulate
hotspots
additional
long‐range
local
field
effect
is
proposed.
Stable
opal
photonic
crystal
(OPC)
developed
for
Au
deposition,
which
modulates
incident
light
directly,
rather
than
merely
optimizing
nanostructure,
thereby
significantly
enhancing
generation.
OPC
substrate
introduces
structural
discreteness
deposited
layer,
also
effectively
improving
intensity.
layer
prepared
direct
evaporation
can
detect
signal
molecules
adsorption
concentration
of
10
−9
m
.
The
properties
identical
are
further
enhanced
66.8
times
effect.
coupling
between
localized
surface
plasmon
resonance
(LSPR)
induces
strong
elastic
photons
over
large
range,
substantially
300
nm
away
from
surface,
facilitating
detection
larger‐sized
objects.
Dual‐local
modulating
both
LSPR
photons,
enhances
nanostructures,
offering
broader
range
compared
conventional
strategies,
providing
an
approach
practical
application.
