A Target Responsive Metal Organic Framework Derived Bimetallic Apta-Switch for Reagentless Molecular Recognition
Langmuir,
Год журнала:
2025,
Номер
unknown
Опубликована: Янв. 1, 2025
By
integrating
iron-cobalt
squarate
bimetallic
metal-organic
framework
(Fe-Co-SqBMoF)
based
smart
material
(SM)
with
functional
DNA
(fDNA),
we
designed
a
target
responsive
fDNA@Fe-Co-SqBMoF
bioelectrode
that
exhibits
recognition
induced
switchable
response
to
serve
as
reagentless
single
step
electrochemical
apta-switch
(REA).
The
construct
takes
advantage
of
fDNA
ability
bind
and
concentrate
on
the
receptor
interface,
while
Fe-Co-SqBMoF@SM
multifeatures
an
immobilization
matrix
signal
generating
switch.
Fe-Co-SqBMoF
was
introduced
prepare
redox
active
pencil
graphite
electrode
(PGE),
(aptamer)
decorated
PGE
impart
specificity
selectivity.
synthesis
characterized
through
X-ray
diffraction
(XRD),
Fourier
transform
infrared
(FTIR)
spectroscopy,
micro-Raman
dynamic
light
scattering
(DLS),
UV-visible
(UV-vis)
analysis,
each
decoration
fabrication
via
field
emission
scanning
electron
microscopy
(FE-SEM),
static
water
contact
angle
measurements,
cyclic
voltammetry
(CV),
impedance
spectroscopy
(EIS).
To
explore
potential
application
bioelectrode,
REA
for
detection
aflatoxin
B1
(AFB1)
which
permitted
AFB1
in
linear
range
0.7-1000
pg/mL
LOD
0.54
pg.
practical
applicability
demonstrated
milk
samples.
Язык: Английский
Study of Indium Tin Oxide Thin Film as Fluorescence Enhancers for Optical Biosensing in Water Quality Analysis
Lecture notes in electrical engineering,
Год журнала:
2025,
Номер
unknown, С. 63 - 70
Опубликована: Янв. 1, 2025
Язык: Английский
Sub-ppm Photonic Sensor for Water Quality Control: Feasibility Study on Zinc and Lead Detection
Lecture notes in electrical engineering,
Год журнала:
2025,
Номер
unknown, С. 109 - 115
Опубликована: Янв. 1, 2025
Язык: Английский
Conjugated Polymer-Based Smart Biosensors for Pathogen Detection in Food Sector
Food Analytical Methods,
Год журнала:
2025,
Номер
unknown
Опубликована: Фев. 22, 2025
Язык: Английский
Evolution and recent development of cellulose-modified, nucleic acid-based and green nanosensors for trace heavy metal ion analyses in complex media: A review
International Journal of Biological Macromolecules,
Год журнала:
2025,
Номер
unknown, С. 141745 - 141745
Опубликована: Март 1, 2025
Язык: Английский
Design, Simulation, and Comparison of Optofluidics & Sensing Schemes for Integrated Optic Biosensors
Optics Communications,
Год журнала:
2025,
Номер
unknown, С. 131742 - 131742
Опубликована: Март 1, 2025
Язык: Английский
A robust and simple non-enzymatic electrochemical sensor based on carbon dots-metal oxide composite for the detection of metronidazole traces in food products
Food Chemistry,
Год журнала:
2024,
Номер
460, С. 140297 - 140297
Опубликована: Июль 2, 2024
Язык: Английский
Optimizing Stereolithography Printing Parameters for Enhanced Microfluidic Chip Quality
Smart and Sustainable Manufacturing Systems,
Год журнала:
2024,
Номер
8(1), С. 136 - 149
Опубликована: Дек. 30, 2024
ABSTRACT
In
the
pursuit
of
innovative
biosensing
technologies
for
critical
applications
such
as
early
breast
cancer
detection,
development
efficient
and
portable
devices
is
crucial.
This
work
describes
a
unique
stereolithography
(SLA)-based
three-dimensional–printed
microfluidic
device
intended
particularly
optofluidic
with
just
microliter
quantities
blood,
similar
to
diabetes
monitoring
devices.
Unlike
typical
cumbersome
lab
equipment
Biacore
machine,
which
needs
large
blood
sample
volumes
laboratory
processing,
technology
allows
patient-operated,
at-home
testing,
decreasing
requirement
hospital
visits.
The
main
contribution
this
study
optimize
SLA
printing
parameters,
namely
exposure
duration,
in
order
improve
chip’s
transparency
channel
quality.
improvement
exact
immobilization
biorecognition
components
within
channels,
resulting
sensitive
biomarker
detection.
By
extending
we
considerably
increase
structural
integrity
optical
clarity
are
successful
biosignal
transduction
labeled
sensing
applications.
not
only
leads
cheaper
cost
faster
manufacturing
compared
conventional
but
also
offers
increased
performance
real
bio-sensing
Thus,
our
represents
big
step
forward
accessible,
efficient,
compact
early-stage
illness
diagnosis,
outperforming
existing
lab-based
diagnostics.
Язык: Английский