Prophage-encoded antibiotic resistance genes are enriched in human-impacted environments

Nature Communications, Год журнала: 2024, Номер 15(1)

Опубликована: Сен. 27, 2024

Язык: Английский

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Adaptive expression of phage auxiliary metabolic genes in paddy soils and their contribution toward global carbon sequestration

Proceedings of the National Academy of Sciences, Год журнала: 2024, Номер 121(49)

Опубликована: Ноя. 27, 2024

Habitats with intermittent flooding, such as paddy soils, are crucial reservoirs in the global carbon pool; however, effect of phage–host interactions on biogeochemical cycling soils remains unclear. Hence, this study applied multiomics and datasets integrated validation experiments to investigate community potential phages impact sequestration soils. The results demonstrated that soil harbor a diverse abundant repertoire auxiliary metabolic genes (AMGs) associated fixation, comprising 23.7% identified AMGs. successful annotation protein structures promoters further suggested an elevated expression these within their bacterial hosts. Moreover, environmental stressors, heavy metal contamination, cause genetic variation up-regulate fixation AMGs, by significant enrichment related metabolites ( P < 0.05). Notably, findings indicate lysogenic infecting carbon-fixing hosts increased 10.7% under stress. In addition, situ isotopic labeling induced mitomycin-C revealed increasing concentrations, 13 CO 2 emissions from treatment added phage decreased approximately 17.9%. contrast, C-labeled microbial biomass content average 35.4% compared control. These suggest prominently influence cycle, particularly change conditions. This research enhances our understanding cooperation driving amid evolving

Язык: Английский

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Viral and Bacterial Community Dynamics in Food Waste and Digestate from Full-Scale Biogas Plants

Environmental Science & Technology, Год журнала: 2024, Номер 58(29), С. 13010 - 13022

Опубликована: Июль 11, 2024

Anaerobic digestion (AD) is commonly used in food waste treatment. Prokaryotic microbial communities AD of have been comprehensively studied. The role viruses, known to affect dynamics and metabolism, remains largely unexplored. This study employed metagenomic analysis recovered 967 high-quality viral bins within digestate derived from 8 full-scale biogas plants. diversity was higher digestate. In silico predictions linked 20.8% viruses host populations, highlighting possible virus predators key functional microbes. Lineage-specific virus-host ratio varied, indicating that infection might differentially responses the varying process parameters. Evidence for virus-mediated gene transfer identified, emphasizing potential controlling microbiome. altered specific parameters, potentially promoting a shift lifestyle lysogenic lytic. Viruses encoding auxiliary metabolic genes (AMGs) were involved carbon nutrient cycling, most AMGs transcriptionally expressed digestate, meaning with active states likely actively AD. These findings provided comprehensive profile bacterial expanded knowledge interactions between hosts

Язык: Английский

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Large-scale Analysis of Predicted Phages in 1497 Lactiplantibacillus plantarum Strains - Unveiling the Functional Diversity and Conservation of Prophage Genomes

LWT, Год журнала: 2025, Номер unknown, С. 117334 - 117334

Опубликована: Янв. 1, 2025

Язык: Английский

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Viral Auxiliary Roles in Hydrolytic and Biosynthetic Metabolism Regulate Prokaryotic Microbial Interactions in Anaerobic Digestion

Water Research, Год журнала: 2025, Номер 274, С. 123140 - 123140

Опубликована: Янв. 13, 2025

Язык: Английский

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Response of Soil Phage Communities and Prokaryote–Phage Interactions to Long-Term Drought

Environmental Science & Technology, Год журнала: 2025, Номер unknown

Опубликована: Фев. 7, 2025

Soil moisture is a fundamental factor affecting terrestrial ecosystem functions. In this study, microscopic enumeration and joint metaviromic metagenomic sequencing were employed together to investigate the impact of prolonged drought on soil phage communities their interactions with prokaryotes in subtropical evergreen forest. Our findings revealed marked reduction abundances prokaryotic viral-like particles, by 73.1% 75.2%, respectively, significantly altered structure under drought. Meanwhile, substantially increased fraction containing lysogenic phages 163%, as well proportion temperate phages. Nonetheless, likely amplified negative prokaryote-phage given nearly doubled links co-occurrence network, higher frequency diversity antiphage defense systems found genomes. Under drought, exerted greater top-down control typical k-strategists including Acidobacteria Chloroflexi. Moreover, phage-encoded auxiliary metabolic genes may host metabolism biosynthesis-related Collectively, study underscore profound interactions. These results also emphasize importance managing levels during amendment microbiome manipulation account for influence

Язык: Английский

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The Gut Virome and Human Health: From Diversity to Personalized Medicine

Engineering Microbiology, Год журнала: 2025, Номер unknown, С. 100191 - 100191

Опубликована: Фев. 1, 2025

Язык: Английский

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Whole Genome Sequencing of the Novel Polyvalent Bacteriophage Malk1: A Powerful Biocontrol Agent for Water Pollution

Water Research, Год журнала: 2025, Номер 276, С. 123259 - 123259

Опубликована: Фев. 9, 2025

Язык: Английский

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Comparative Genomic Analysis of 66 Bacteriophages Infecting Morganella morganii Strains

Current Microbiology, Год журнала: 2025, Номер 82(4)

Опубликована: Фев. 15, 2025

Язык: Английский

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Soil core taxa and their regulatory microbial competition determine wheat health under warming fluctuations

Plant and Soil, Год журнала: 2025, Номер unknown

Опубликована: Фев. 20, 2025

Язык: Английский

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