The relationship between changes in functional connectivity gradients and cognitive-emotional disorders in sudden sensorineural hearing loss DOI Creative Commons
Biao Li, Xiaomin Xu, Yuanqing Wu

и другие.

Brain Communications, Год журнала: 2024, Номер 6(5)

Опубликована: Янв. 1, 2024

Abstract Sudden sensorineural hearing loss, a prevalent emergency in otolaryngology, is known to potentially precipitate cognitive and emotional disorders affected individuals. Extensive research has documented the phenomenon of cortical functional reorganization patients with sudden loss. However, potential link between this neural remodelling cognitive–emotional remains unclear. To investigate issue, 30 bilateral loss healthy adults were recruited for study. We collected clinical data resting-state magnetic resonance imaging from participants. Gradient mapping analysis was employed calculate first three gradients each subject. Subsequently, gradient changes compared controls at global, regional network levels. Finally, we explored relationship values variables. The results revealed that global level, did not exhibit significant differences primary but showed state compression second third gradients. At exhibited reduction temporal pole ventral prefrontal cortex, which closely related neuro-scale scores. Regarding show instead displayed control default mode This study disruptions hierarchy alterations connectivity associated disturbances patients. These findings provide new evidence understanding occurs

Язык: Английский

Neurocognitive Outcomes in Young Adults with Cochlear Implants: The Role of Early Language Access and Crossmodal Plasticity DOI

Geo Kartheiser,

Kayla Cormier,

Don Bell-Souder

и другие.

Hearing Research, Год журнала: 2024, Номер 451, С. 109074 - 109074

Опубликована: Июль 3, 2024

Язык: Английский

Процитировано

3
Neural correlates of age‐related hearing loss: An MRI and FDG‐PET study DOI
Ryota Sakurai, Yuri Kim, Maki Nishinakagawa

и другие.

Geriatrics and gerontology international/Geriatrics & gerontology international, Год журнала: 2025, Номер 25(2), С. 300 - 306

Опубликована: Янв. 5, 2025

Age-related hearing loss (ARHL) is a common problem among older adults and contributes to adverse health outcomes such as cognitive impairment. However, the neural mechanisms underlying ARHL remain unclear. We aimed reveal structural metabolic (i.e., activity) correlates of using magnetic resonance imaging (MRI) positron emission tomography with 18F-fluorodeoxyglucose (FDG-PET). A total 162 community-dwelling without cerebral disorders or impairment (Mini-Mental State Examination score < 24) were included in this study. Auditory acuity was measured pure-tone average (PTA) thresholds for better-hearing ear 0.5-4-kHz tones. defined PTA >40 dB greater than moderate loss). The participants then underwent MRI FDG-PET at rest assess changes brain structure activity associated ARHL. Among participants, 27 (16.6%) had region-of-interest analysis focusing on bilateral superior temporal gyrus showed significantly lower glucose metabolism region, including auditory cortex (BA 41 42), those In contrast, no significant differences observed between groups. These findings suggest that, prior changes, effects may manifest activity, which strongly reflected regions involved processing. It possible that first alters auditory-related owing reduced stimulation. Geriatr Gerontol Int 2025; 25: 300-306.

Язык: Английский

Процитировано

0
Visual Reliance in Severe Hearing Loss: Visual Evoked Potentials (VEPs) Study DOI Creative Commons
Takwa A. Gabr, Ahmed Osama Hashem, Sherihan Rezk Ahmed

и другие.

Audiology Research, Год журнала: 2025, Номер 15(1), С. 3 - 3

Опубликована: Янв. 13, 2025

Peripheral hearing loss is associated with the cross-modal re-organization of auditory cortex, which can occur in both pre- and post-lingual deaf cases. Background/Objectives: Whether to rely on visual cues cases severe adequate amplification a matter debate. So, this study aims evoked potentials (VEPs) children or profound HL, whether fitted HAs CIs. Methods: This included three groups matched age gender: normal hearing, thresholds >70 dBHL power HAs, All were subjected pure tone audiometry (aided unaided), speech discrimination scores, ophthalmic examinations, (VEPs). Results: SD% scores significantly improved use VCs CI HL groups, higher P100 amplitude VEPs (more CIs). Conclusions: Cross-modal reorganization degrees great benefit they are

Язык: Английский

Процитировано

0
Effect of Supplemental Language Therapy on Cortical Neuroplasticity and Language Outcomes in Children with Hearing Loss DOI Creative Commons
Anu Sharma, Kayla Cormier, Jim Grigsby

и другие.

Brain Sciences, Год журнала: 2025, Номер 15(2), С. 119 - 119

Опубликована: Янв. 26, 2025

Background/Objectives: The cortical auditory evoked potential P1 response is a biomarker of maturation for tracking longitudinal in children with hearing loss after treatment aids and/or cochlear implants. In conjunction treatments, commonly receive language therapy services. However, the effect on less well studied. Methods: This study explored changes, using response, coinciding utilizing Preschool Language Scales test, following approximately six months supplemental listening and spoken services 39 or Results: Following therapy, latencies significantly decreased all children, at rate found to be faster than expected typical maturation. scores also improved beyond effects were correlated therapy. Overall, this made greater gains 9 10 total expressive communication. A subgroup analysis revealed that implants showed lower their chronological age while obtained not different follow-up. Conclusions: results from resulted more abilities CAEP can objectively track neuroplastic changes as function provided CIs.

Язык: Английский

Процитировано

0
Unraveling the impact of congenital deafness on individual brain organization DOI Open Access
Lénia Amaral,

Wang Xiao-sha,

Bi Yanchao

и другие.

Опубликована: Фев. 4, 2025

Research on brain plasticity, particularly in the context of deafness, consistently emphasizes reorganization auditory cortex. However, a critical question arises: to what extent do all individuals with deafness show same level reorganization? To address this question, we examined individual differences functional connectivity (FC), specifically from deprived Our findings demonstrate remarkable differentiation between deriving absence shared experiences, resulting heightened FC variability among deaf individuals, compared more consistent hearing group. Notably, language regions becomes diverse across deafness. This does not stem delayed acquisition, as it is found native signers, who are exposed rich natural since birth. comparing diversity signers and were early development, that experience also impacts differences, although moderate extent. Overall, our research points out intricate interplay plasticity shedding light ways manifests individuals. It further joins blindness, showing affected by sensory experience. Finally, these highlight importance considering personalized rehabilitation for loss.

Язык: Английский

Процитировано

0
Regional gray matter thickness correlations of the hearing and deaf feline brains DOI Creative Commons

Stephen G Gordon,

Alessandra Sacco, Stephen G. Lomber

и другие.

Neuroimage Reports, Год журнала: 2025, Номер 5(1), С. 100239 - 100239

Опубликована: Фев. 8, 2025

Язык: Английский

Процитировано

0
The neural characteristics influencing literacy outcome in children with cochlear implants DOI Creative Commons
Nabin Koirala,

Jacy Manning,

Sara Neumann

и другие.

Brain Communications, Год журнала: 2025, Номер 7(2)

Опубликована: Янв. 1, 2025

Early hearing intervention in children with congenital loss is critical for improving auditory development, speech recognition and both expressive receptive language, which translates into better educational outcomes quality of life. In receiving aids or cochlear implants, adaptive potentially maladaptive neural reorganization can mitigate higher-level functions that impact reading. The focus the present study was to dissect underpinnings reading networks implants assess how these mediate ability implants. Cortical activity obtained using naturalistic stimuli from 75 (50 implant recipients, aged 7-17, 25 age-matched typical hearing) functional near-infrared spectroscopy. Assessment basic skill completed Reading Inventory Scholastic Evaluation. We computed directed connectivity haemodynamic reading-associated anterior posterior brain regions time-frequency causality estimation method known as temporal partial coherence. influence implant-related clinical measures on outcome extent mediated effects were examined structural equation modelling. Our findings reveal timing (e.g. age first aid) significantly influenced their ability. Furthermore, reading-related processes (word decoding, vocabulary, morphology sentence processing) substantially by within circuits. Notably, differed across various skills. Hearing age, defined at a participant received adequate access sound, initial implantation emerged robust predictors proficiency. current one identify characteristics emphasize importance duration deafness early enhancing strengthening network connections. However, evidence further suggested such positive influences cannot fully offset detrimental deprivation. Consequently, additional, perhaps more specialized, interventions might be necessary maximize benefits prosthetic intervention.

Язык: Английский

Процитировано

0
Visual Cortical Processing in Children with Early Bilateral Cochlear Implants: A VEP Analysis DOI Creative Commons

Ola Badarni-Zahalka,

Ornella Dakwar-Kawar, Cahtia Adelman

и другие.

Children, Год журнала: 2025, Номер 12(3), С. 278 - 278

Опубликована: Фев. 25, 2025

Background/Objectives: Cochlear implantation is the primary treatment for severe-to-profound hearing loss, yet outcomes vary significantly among recipients. While visual–auditory cross-modal reorganization has been identified as a contributing factor to this variability, its impact in early-implanted children remains unclear. To address knowledge gap, we investigated visual processing and relationship with auditory who received early bilateral cochlear implants. Methods: examine potential reorganization, recorded evoked potentials (VEPs) response pattern-reversal stimuli 25 implants (CIs) (mean age: 1.44 years) 28 age-matched normal-hearing (NH) controls. Analysis focused on both occipital region of interest (ROI: O1, OZ, O2 electrode sites) right temporal ROI, examining VEP components their correlation speech perception outcomes. Results: Unlike previous studies later-implanted children, overall ROI showed no significant differences between groups. However, left (O1) revealed reduced P1 amplitudes delayed N1 latencies CI users. Importantly, O1 latency negatively correlated speech-in-noise performance (r = −0.318; p 0.02). The groups Conclusions: Early appears preserve global processing, suggesting minimal maladaptive reorganization. subtle alterations may influence outcomes, highlighting importance intervention complex nature sensory integration population.

Язык: Английский

Процитировано

0
Unraveling the impact of congenital deafness on individual brain organization DOI Creative Commons
Lénia Amaral, Xiaosha Wang, Yanchao Bi

и другие.

eLife, Год журнала: 2025, Номер 13

Опубликована: Март 12, 2025

Research on brain plasticity, particularly in the context of deafness, consistently emphasizes reorganization auditory cortex. But to what extent do all individuals with deafness show same level reorganization? To address this question, we examined individual differences functional connectivity (FC) from deprived Our findings demonstrate remarkable differentiation between deriving absence shared experiences, resulting heightened FC variability among deaf individuals, compared more consistent hearing group. Notably, language regions becomes diverse across deafness. This does not stem delayed acquisition; it is found native signers, who are exposed natural since birth. However, comparing diversity signers and were early development, that experience also impacts differences, although a moderate extent. Overall, our research points out intricate interplay plasticity shedding light ways manifests individuals. It joins increased blindness highlights importance considering personalized rehabilitation for sensory loss.

Язык: Английский

Процитировано

0
TOWARDS A UNIFIED METHOD OF ASSESSING EARLY AUDITORY DEVELOPMENT AFTER COCHLEAR IMPLANTATION: MEASURING RELATIVE DELAY DOI Creative Commons
Anita Obrycka

Journal of Hearing Science, Год журнала: 2025, Номер 14(4), С. 9 - 21

Опубликована: Март 28, 2025

Current research on auditory development in children with profound sensorineural hearing loss emphasizes the importance of providing effective stimulation as early possible, preferably before 12 months age. Cochlear implants have been identified most method for delivering sound to system these children. To minimize neurological consequences congenital it is vital monitor all stages right from moment implantation. The LittlEARS Auditory Questionnaire, by measuring ability up 24 age, facilitates such an assessment. In this paper multiple approaches reporting results are reviewed. Two difficulties interpreting cohorts cochlear implanted identified, one related variability and second age child at intervention. overcome a calculating “relative delay” proposed. should facilitate between-group comparisons single or multicenter studies, well improve meta-analysis data evidence-based practice.

Язык: Английский

Процитировано

0