Future Directions for Quantitative Systems Pharmacology

Handbook of experimental pharmacology, Год журнала: 2024, Номер unknown

Опубликована: Янв. 1, 2024

Язык: Английский

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New investigational drugs to treat Sjogren's syndrome: lessons learnt from immunology

Expert Opinion on Investigational Drugs, Год журнала: 2024, Номер 33(2), С. 105 - 114

Опубликована: Янв. 31, 2024

Sjögren's syndrome is a heterogeneous autoimmune condition that impairs quality of life because dryness, fatigue, pain, and systemic involvements. Current treatment largely depends on empirical evidence, with no effective therapy approved. Clinical trials targeted drugs often fail to report efficacy due common factors.

Язык: Английский

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Les apports de l’intelligence artificielle aux nouveaux traitements contre les maladies auto-immunes

médecine/sciences, Год журнала: 2024, Номер 40(5), С. 414 - 416

Опубликована: Май 1, 2024

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The mechanism of action and chemical synthesis of FDA newly approved drug molecules

Drug Development Research, Год журнала: 2024, Номер 85(6)

Опубликована: Сен. 1, 2024

Abstract In 2023, the U.S. Food and Drug Administration has approved 29 small molecule drugs. These newly drugs possess distinct scaffolds, thereby exhibiting diverse mechanisms of action binding modalities. Moreover, marketed have always been an important source new drug development creative inspiration, fostering analogous endeavors in discovery that potentially extend to clinical indications. Therefore, conducting a comprehensive evaluation approval experience associated information will facilitate expedited identification highly potent molecules. this review, we comprehensively summarized relevant regarding applications, chemical synthesis drugs, with aim providing promising structural basis design inspiration for pharmaceutical chemists.

Язык: Английский

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Artificial Intelligence in Immunology: Predictive Models for Immune System Disorders

Опубликована: Окт. 25, 2024

Язык: Английский

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