Molecular mechanisms of environmental exposures and human disease

Nature Reviews Genetics, Год журнала: 2023, Номер 24(5), С. 332 - 344

Опубликована: Янв. 30, 2023

Язык: Английский

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Principles and Applicability of Integrated Remediation Strategies for Heavy Metal Removal/Recovery from Contaminated Environments

Journal of Plant Growth Regulation, Год журнала: 2022, Номер 42(6), С. 3419 - 3440

Опубликована: Сен. 21, 2022

Abstract Contamination of agricultural soils with heavy metals present lethal consequences in terms diverse ecological and environmental problems that entail entry metal food chain, soil deterioration, plant growth suppression, yield reduction alteration microbial community. Metal polluted have become a major concern for scientists around the globe. In more recent times, armed new knowledge understanding, removal using different applications has emerged as solution waste treatment contaminant remediation water soil. However, description toxicity to plants its degradation from is limited. There are number reports literature where PGP bacterial inoculation various chelating agents improves accumulation it’s detoxification parts without influencing growth. Therefore, there need select some useful chemicals which possess potential improve well expedite phytoremediation metals. this review, we discussed mechanisms possessed by promote We anticipate analysis interconnected systems will lead discovery research fields.

Язык: Английский

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Comprehensive analytical review of heavy metal removal efficiency using agricultural solid waste-based bionanocomposites

Nano-Structures & Nano-Objects, Год журнала: 2024, Номер 38, С. 101220 - 101220

Опубликована: Май 1, 2024

Язык: Английский

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Hydrogel-based materials as antibacterial agents and super adsorbents for the remediation of emerging pollutants: A comprehensive review

Emerging contaminants, Год журнала: 2024, Номер 10(3), С. 100336 - 100336

Опубликована: Март 29, 2024

Hydrogels have various potential applications due to their unique characteristics and recently, hydrogels been utilized as adsorbents in wastewater treatment because of ability remove contaminants from water. Constructing strong with high adsorption capabilities is crucial for effective treatment. Scientists researchers are working improve the properties by incorporating inorganic elements into polymer networks, which further reduces costs well simplifies preparation. Natural polymers like starch alginate widespread economic biological advantages, such biodegradability, biocompatibility, reduced toxicity, environmental friendliness, low cost. The pollutants onto use antimicrobial agents has garnered significant attention. This review paper summarizes latest studies on using endocrine-disrupting chemicals (EDCs), persistent organic (POPs), other emerging water environments along agents. In first step, different classes characterization techniques discussed. Next elaborated understand how these can be a candidate activities. While discussing application hydrogels, isothermal, kinetics thermodynamics models discussed highlight mechanism nature forces involved pollutants. Further simulations DFT MD get more holistic understanding hydrogels. A limited number Monte Carlo computational fluid dynamics (CFD) so it important explore variety methods gain comprehensive process

Язык: Английский

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Emerging insights into the impacts of heavy metals exposure on health, reproductive and productive performance of livestock

Frontiers in Pharmacology, Год журнала: 2024, Номер 15

Опубликована: Март 19, 2024

Heavy metals, common environmental pollutants with widespread distribution hazards and several health problems linked to them are distinguished from other toxic compounds by their bioaccumulation in living organisms. They pollute the food chain threaten of animals. Biologically, heavy metals exhibit both beneficial harmful effects. Certain essential such as Co, Mn, Se, Zn, Mg play crucial roles vital physiological processes trace amounts, while others like As, Pb, Hg, Cd, Cu widely recognized for properties. Regardless functions, an excess intake all beyond tolerance limit can lead toxicity. Animals face exposure through contaminated feed water, primarily a result anthropogenic pollution. After ingestion persist body extended duration nature dictates whether they induce acute or chronic, clinical subclinical, subtle toxicities. The effects disruption cellular homeostasis generation free radicals that develop oxidative stress. In cases metal poisoning, characteristic symptoms may arise, potentially culminating death animals corresponding necropsy findings. Chronic toxicities manifest decline overall condition scoring decrease production potential Elevated levels consumable animal products raise public concerns. Timely diagnosis, targeted antidotes, management strategies significantly mitigate impact on livestock health, productivity, reproductive performance.

Язык: Английский

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Mitochondrial health quality control: measurements and interpretation in the framework of predictive, preventive, and personalized medicine

The EPMA Journal, Год журнала: 2022, Номер 13(2), С. 177 - 193

Опубликована: Май 12, 2022

Abstract Mitochondria are the “gatekeeper” in a wide range of cellular functions, signaling events, cell homeostasis, proliferation, and apoptosis. Consequently, mitochondrial injury is linked to systemic effects compromising multi-organ functionality. Although stress common for many pathomechanisms, individual outcomes differ significantly comprising spectrum associated pathologies their severity grade. highly ambitious task paradigm shift from reactive predictive, preventive, personalized medicine (PPPM/3PM) distinguish between disease predisposition progression under circumstances, resulting compromised health followed by mitigating measures tailored individualized patient profile. For successful implementation PPPM concepts, robust parameters essential quantify sustainability. The current article analyses added value Mitochondrial Health Index (MHI) Bioenergetic (BHI) as potential systems relevant development its Based on pathomechanisms related context primary, secondary, tertiary care, broad conditions can benefit quantification using MHI/BHI prototype be further improved. Following that: planned pregnancies (improved mother offspring health), suboptimal with reversible damage, life-style patterns metabolic syndrome(s) predisposition, multi-factorial conditions, genotoxic environment, ischemic stroke unclear aetiology, phenotypic aggressive cancer subtypes, premature aging neuro/degeneration, acute infectious diseases such COVID-19 pandemics, among others.

Язык: Английский

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Advances in biological methods for the sequestration of heavy metals from water bodies: A review

Environmental Toxicology and Pharmacology, Год журнала: 2022, Номер 94, С. 103927 - 103927

Опубликована: Июль 6, 2022

Язык: Английский

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Ecological risk assessment of aquatic organisms induced by heavy metals in the estuarine waters of the Pearl River

Scientific Reports, Год журнала: 2023, Номер 13(1)

Опубликована: Июнь 5, 2023

Abstract With the rapid economic development of China's coastal areas and growth industry population, problem heavy metal contamination in estuarine waters is increasing sensitivity seriousness. In order to accurately quantitatively describe current status identify sensitive aquatic organisms with high ecological risks, five metals eight estuaries Pearl River were monitored at monthly intervals from January December 2020, risks induced by evaluated using Risk quotients (RQ) species distributions (SSD) methods. The results showed that concentrations As, Cu, Pb, Hg Zn (0.65–9.25) μg/L, (0.07–11.57) (0.05–9.09) (< 0.40) μg/L (0.67–86.12) respectively. exception Jiaomen water, other each sampling site met or exceed water quality standard Grade II. Pb generally low estuary, but individual are subject elevated due Cu Zn. content has a lethal effect on crustaceans Temora Stylifera , serious impact mollusks Corbicula Fluminea certain Corophium sp. fish Sparus aurata . Heavy levels joint (msPAF) Humen, Jiaomen, Hongqimen, Hengmen slightly higher than estuaries, Yamen estuary had lowest contration risk. Research findings can serve as basis for formulating standards protecting biodiversity Estuary.

Язык: Английский

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Biological roles of soil microbial consortium on promoting safe crop production in heavy metal(loid) contaminated soil: A systematic review

The Science of The Total Environment, Год журнала: 2023, Номер 912, С. 168994 - 168994

Опубликована: Дек. 2, 2023

Язык: Английский

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Environmental health hazards of untreated livestock wastewater: potential risks and future perspectives

Environmental Science and Pollution Research, Год журнала: 2024, Номер 31(17), С. 24745 - 24767

Опубликована: Март 19, 2024

Язык: Английский

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