Chronic environmental exposure to polystyrene microplastics increases the risk of nonalcoholic fatty liver disease
Toxicology,
Год журнала:
2025,
Номер
511, С. 154067 - 154067
Опубликована: Янв. 25, 2025
Язык: Английский
Microplastics in our diet: A growing concern for human health
The Science of The Total Environment,
Год журнала:
2025,
Номер
968, С. 178882 - 178882
Опубликована: Фев. 22, 2025
Язык: Английский
Biological Effects of Micro-/Nano-Plastics in Macrophages
Nanomaterials,
Год журнала:
2025,
Номер
15(5), С. 394 - 394
Опубликована: Март 4, 2025
The
environmental
impact
of
plastics
is
worsened
by
their
inadequate
end-of-life
disposal,
leading
to
the
ubiquitous
presence
micro-
(MPs)
and
nanosized
(NPs)
plastic
particles.
MPs
NPs
are
thus
widely
present
in
water
air
inevitably
enter
food
chain,
with
inhalation
ingestion
as
main
exposure
routes
for
humans.
Many
recent
studies
have
demonstrated
that
gain
access
several
body
compartments,
where
they
taken
up
cells,
increase
production
reactive
oxygen
species,
lead
inflammatory
changes.
In
most
tissues,
resident
macrophages
engage
first
approach
foreign
materials,
this
interaction
largely
affects
subsequent
fate
material
possible
pathological
outcomes.
On
other
hand,
organizers
controllers
both
responses
tissue
repair.
Here,
we
aim
summarize
available
information
on
NPs.
Particular
attention
will
be
devoted
consequences
macrophage
viability
functions,
well
implications
pathology.
Язык: Английский
Association between microplastics exposure and depressive symptoms in college students
Ecotoxicology and Environmental Safety,
Год журнала:
2025,
Номер
295, С. 118142 - 118142
Опубликована: Апрель 1, 2025
Microplastics
(MP)
are
pervasive
environmental
pollutants
that
have
raised
concerns
regarding
their
potential
health
effects.
However,
limited
studies
investigated
the
relationship
between
MP
exposure
and
depression,
particularly
in
college
students.
Our
study
aims
to
examine
association
depressive
symptoms
A
total
of
1420
students
from
Jiangsu
College
Nursing,
China,
were
included
this
cross-sectional
study.
Depressive
assessed
using
Patient
Health
Questionnaire-2
(PHQ-2),
was
estimated
based
on
daily
airborne
concentration
drinking-water
levels.
Multivariate
logistic
regression
models
used
estimate
associations
symptoms.
The
prevalence
among
61.8
%.
median
(interquartile
range)
17403.7
(14174.8-20995.9)
particles/day.
Airborne
exhibited
positive
with
symptoms,
while
no
significant
found
Compared
participants
lowest
quartile
exposure,
those
highest
had
38
%
higher
odds
experiencing
(odds
ratio
[OR]
=
1.38,
95
CI:
1.21-1.57).
When
treated
as
a
continuous
variable,
each
1000-particle
increase
associated
7.0
(OR
1.07,
1.04-1.10).
Stratified
analyses
indicated
stronger
male
freshmen.
This
suggests
is
contributing
factor
for
Язык: Английский
Chemical Food Safety in Europe Under the Spotlight: Principles, Regulatory Framework and Roadmap for Future Directions
Foods,
Год журнала:
2025,
Номер
14(9), С. 1628 - 1628
Опубликована: Май 5, 2025
Chemical
food
safety
is
a
fundamental
pillar
of
public
health,
regulatory
governance,
and
economic
stability,
with
far-reaching
implications
for
human,
animal,
environmental
well-being.
In
the
matter
chemicals
in
chain,
European
Union
(EU)
has
established
one
most
sophisticated
robust
frameworks
to
ensure
balance
consumer
protection
scientific
advancements
industry
needs.
This
review
provides
holistic
analysis
EU
chemical
scenario,
examining
its
framework,
key
risk
assessment
methodologies,
roles
critical
institutions
involved
monitoring,
enforcement,
policymaking.
The
new
evolving
challenges
safety,
including
transparency,
cumulative
assessment,
emerging
contaminants,
were
discussed.
Special
attention
given
major
classes
substances
food,
their
oversight,
principles
guiding
as
well
role
actors,
agencies,
official
laboratories,
competent
authorities.
work
offers
an
updated
integrated
EU,
uniquely
combining
regulatory,
scientific,
enforcement
perspectives
providing
structured
roadmap
future
directions.
Язык: Английский
Mitigating Microplastic-Induced Organ Damage: Mechanistic Insights from the Microplastic-Macrophage Axes
Yinxing Cui,
Yuqi Wu,
Shi Pan
и другие.
Redox Biology,
Год журнала:
2025,
Номер
unknown, С. 103688 - 103688
Опубликована: Май 1, 2025
Язык: Английский
Microplastics as Emerging Contaminants and Human Health: Exploring Functional Nutrition in Gastric–Colon–Brain Axis Cancer
Toxics,
Год журнала:
2025,
Номер
13(6), С. 438 - 438
Опубликована: Май 26, 2025
Microplastics
(MPs),
emerging
contaminants
of
significant
global
concern,
have
a
substantially
increased
environmental
impact
due
to
their
biological
persistence
and
accumulation
in
the
body.
Exposure
MPs
has
been
associated
with
oxidative
stress,
systemic
inflammation,
cellular
dysfunction,
notably
affecting
critical
tissues
such
as
stomach,
colon,
brain.
This
review
explores
correlation
between
cancer
risk
along
gastric–colon–brain
axis,
identifying
signaling
pathways
altered
by
MP
exposure.
Furthermore,
it
highlights
role
functional
nutrition
bioactive
flavonoids—including
chlorogenic
acid,
coumaric
naringin—as
well
use
highly
bioavailable
combined
polyphenol
nanoparticles
potential
detoxifying
agents.
Functional
nutrients
are
effective
enhancing
resilience
against
reactive
oxygen
species
(ROS)
production
MP-induced
toxicity,
offering
protective
effects
at
gastric,
intestinal,
brain
barriers.
Activation
Nrf2
pathway
compounds
promotes
expression
enzymes,
suggesting
promising
nutritional
strategy
mitigate
MP-related
damage.
underscores
how
may
represent
viable
therapeutic
approach
reduce
harmful
The
integration
advanced
technologies—such
microfluidic
systems,
organ-on-a-chip
platforms,
machine
learning—and
identification
key
molecular
targets
lay
foundation
for
developing
preventive
personalized
medicine
strategies
aimed
lowering
environmentally
induced
carcinogenesis.
Язык: Английский