Rising Concern About the Carcinogenetic Role of Micro-Nanoplastics DOI Open Access
Lorenzo Ruggieri, Ottavia Amato, Cristina Marrazzo

и другие.

International Journal of Molecular Sciences, Год журнала: 2024, Номер 26(1), С. 215 - 215

Опубликована: Дек. 30, 2024

In recent years, awareness regarding micro-nanoplastics’ (MNPs) potential effects on human health has progressively increased. Despite a large body of evidence the origin and distribution MNPs in environment, their impact remains to be determined. this context, there is major need address carcinogenic risks, since could hypothetically mediate direct indirect effects, latter mediated by particle-linked chemical carcinogens. Currently, field scarce heterogeneous, but reported increased incidence malignant tumors among younger populations, together with ubiquitous environmental abundance MNPs, are rising global concern possible role development progression cancer. review, we provide an overview currently available eco-toxicology, as well methods for identification characterization MNP particulates health-associated focus addition, suggest routes future research order unravel carcinogenetic exposure understand prognostic preventive implications intratumoral MNPs.

Язык: Английский

Chronic environmental exposure to polystyrene microplastics increases the risk of nonalcoholic fatty liver disease DOI
Yujie Shi,

Runyang Hong,

Zhencheng Fan

и другие.

Toxicology, Год журнала: 2025, Номер 511, С. 154067 - 154067

Опубликована: Янв. 25, 2025

Язык: Английский

Процитировано

0

Micro- and Nano-Plastic-Induced Adverse Health Effects on Lungs and Kidneys Linked to Oxidative Stress and Inflammation DOI Creative Commons
Seung Eun Lee,

Do Yun Kim,

Taek Seung Jeong

и другие.

Life, Год журнала: 2025, Номер 15(3), С. 392 - 392

Опубликована: Март 3, 2025

Micro- and nano-plastics (MNPs) are small plastic particles that result from the breakdown of larger plastics. They widely dispersed in environment pose a threat to wildlife humans. MNPs present almost all everyday items, including food, drinks, household products. Air inhalation can also lead exposure MNPs. Research animals indicates once absorbed, they spread various organs, liver, spleen, heart, lungs, thymus, reproductive kidneys, even brain by crossing blood–brain barrier. Furthermore, MPs transport persistent organic pollutants or heavy metals invertebrates higher levels food chain. When ingested, additives monomers comprise disrupt essential biological processes human body, thereby leading disturbances endocrine immune systems. During 2019 coronavirus (COVID-19) pandemic, there was significant increase global use polypropylene-based face masks, insufficient waste management exacerbating pollution. This review examines existing research on impact MNP lung kidney health based vitro vivo studies. Over past decades, wide range studies suggest both tissues under healthy diseased conditions. Therefore, this emphasizes need for additional employing multi-approach analyses associated biomarkers mechanisms gain comprehensive precise understanding health.

Язык: Английский

Процитировано

0

Rising Concern About the Carcinogenetic Role of Micro-Nanoplastics DOI Open Access
Lorenzo Ruggieri, Ottavia Amato, Cristina Marrazzo

и другие.

International Journal of Molecular Sciences, Год журнала: 2024, Номер 26(1), С. 215 - 215

Опубликована: Дек. 30, 2024

In recent years, awareness regarding micro-nanoplastics’ (MNPs) potential effects on human health has progressively increased. Despite a large body of evidence the origin and distribution MNPs in environment, their impact remains to be determined. this context, there is major need address carcinogenic risks, since could hypothetically mediate direct indirect effects, latter mediated by particle-linked chemical carcinogens. Currently, field scarce heterogeneous, but reported increased incidence malignant tumors among younger populations, together with ubiquitous environmental abundance MNPs, are rising global concern possible role development progression cancer. review, we provide an overview currently available eco-toxicology, as well methods for identification characterization MNP particulates health-associated focus addition, suggest routes future research order unravel carcinogenetic exposure understand prognostic preventive implications intratumoral MNPs.

Язык: Английский

Процитировано

0