Fluorescent-based nanosensors for selective detection of a wide range of biological macromolecules: A comprehensive review

International Journal of Biological Macromolecules, Год журнала: 2022, Номер 206, С. 115 - 147

Опубликована: Фев. 26, 2022

Thanks to their unique attributes, such as good sensitivity, selectivity, high surface-to-volume ratio, and versatile optical electronic properties, fluorescent-based bioprobes have been used create highly sensitive nanobiosensors detect various biological chemical agents. These sensors are superior other analytical instrumentation techniques like gas chromatography, high-performance liquid capillary electrophoresis for being biodegradable, eco-friendly, more economical, operational, cost-effective. Moreover, several reports also highlighted application in the early detection of biomarkers associated with drug-induced organ damage liver, kidney, or lungs. In present work, we comprehensively overviewed electrochemical that employ nanomaterials (nanoparticles/colloids quantum dots, carbon nanoscaled metal-organic frameworks, etc.) a variety macromolecules based on fluorescent emission spectra. addition, most important mechanisms methods sense amino acids, protein, peptides, enzymes, carbohydrates, neurotransmitters, nucleic vitamins, ions, metals, electrolytes, blood gases, drugs (i.e., anti-inflammatory agents antibiotics), toxins, alkaloids, antioxidants, cancer biomarkers, urinary metabolites urea, uric acid, creatinine), pathogenic microorganisms were outlined compared terms selectivity sensitivity. Altogether, small dimensions capability these nanosensors sensitive, label-free, real-time sensing chemical, biological, pharmaceutical could be array-based screening in-vitro in-vivo diagnostics. Although nanoprobes widely applied determining macromolecules, unfortunately, they many challenges limitations. Efforts must made minimize limitations utilizing an emphasis commercial developments. We believe current review can foster wider incorporation nanomedicine will particular interest researchers working fluorescence technology, material chemistry, coordination polymers, related research areas.

Язык: Английский

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High-performance near-infrared fluorescence probe for fast and specific visualization of harmful sulfite in food, living cells, and zebrafish

Chemical Engineering Journal, Год журнала: 2021, Номер 427, С. 131563 - 131563

Опубликована: Авг. 8, 2021

Язык: Английский

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Naphthalene-based fluorescent probe for on-site detection of hydrazine in the environment

Journal of Hazardous Materials, Год журнала: 2022, Номер 445, С. 130415 - 130415

Опубликована: Ноя. 16, 2022

Язык: Английский

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Luminescent sensors for residual antibiotics detection in food: Recent advances and perspectives

Coordination Chemistry Reviews, Год журнала: 2023, Номер 498, С. 215455 - 215455

Опубликована: Окт. 5, 2023

Antibiotics that possess the capability to inhibit or eradicate bacteria have been widely employed in fields of agriculture and veterinary medicine over years. However, excessive use antibiotics has led significant challenges regarding antibiotic pollution food. Given established risks contamination need for regulatory compliance, various detection techniques emerged, including chromatography, immunoassays, microbiological assays, microfluidic analysis. Among these methods, luminescent analysis using sensors attracted attention due its advantages high sensitivity, selectivity, speed, simplicity, cost-effectiveness. This review aims discuss recent advancements, advantages, limitations detecting Furthermore, it seeks offer valuable insights future research directions this field.

Язык: Английский

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Ultrafast detection of bisulfite by a unique quinolinium-based fluorescent probe and its applications in smartphone-assisted food detection and bioimaging

Talanta, Год журнала: 2024, Номер 282, С. 126977 - 126977

Опубликована: Окт. 1, 2024

Язык: Английский

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A quinolinium-based colorimetric and NIR fluorescent dual-channel sensing platform for specific detection of bisulfite in food, traditional Chinese medicine and living cells

Dyes and Pigments, Год журнала: 2025, Номер unknown, С. 112767 - 112767

Опубликована: Март 1, 2025

Язык: Английский

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A ratiometric supramolecular fluorescent probe for on-site determination of cyfluthrin in real food samples

Chemical Engineering Journal, Год журнала: 2022, Номер 451, С. 139022 - 139022

Опубликована: Сен. 6, 2022

Язык: Английский

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Reversible colorimetric and NIR fluorescent probe for sensing SO2/H2O2 in living cells and food samples

Food Chemistry, Год журнала: 2022, Номер 407, С. 135031 - 135031

Опубликована: Ноя. 23, 2022

Язык: Английский

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Mitochondria-Targeted Fluorescent Turn-On Probe for Rapid Detection of Bisulfite/Sulfite in Water and Food Samples

Journal of Agricultural and Food Chemistry, Год журнала: 2022, Номер 70(16), С. 5159 - 5165

Опубликована: Апрель 14, 2022

Bisulfite (HSO3-)/Sulfite (SO32-) is widely used as a food additive, but excessive use often leads to serious consequences, so the detection of HSO3-/SO32- great importance. In this paper, novel 1,4-diethylpiperazine-modified coumarin-benzopyran derivative (probe QLP) has been synthesized and characterized. PBS (10 mM, pH = 7.4), QLP displays good selectivity sensitive for over various analytes with fluorescent "OFF-ON" rapid responding (2 min), long-wavelength emission (600 nm), limit 177 nM. With treatment HSO3-/SO32-, color solution obviously changes from blue-green yellow, colorless amaranth. The fluorescence-enhanced mechanism qualitatively evaluated by density functional theory calculations using CAM-B3LYP/6-31G (d) method, which reveals that photoinduced electron transfer fluorescence QLP-SO3H adduct. Importantly, nontoxic can be detect in sugar, natural water samples, living cells localized mitochondria monitor mitochondrial level.

Язык: Английский

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A colorimetric and NIR fluorescent probe for ultrafast detecting bisulfite and organic amines and its applications in food, imaging, and monitoring fish freshness

Food Chemistry, Год журнала: 2023, Номер 438, С. 137987 - 137987

Опубликована: Ноя. 18, 2023

Язык: Английский

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