Meta-Biosensor With High Q-Factor Based on Wet Etching for Terahertz Detection DOI
Xueer Chen, Longfang Ye, Daquan Yu

и другие.

IEEE Sensors Journal, Год журнала: 2024, Номер 24(7), С. 9989 - 9997

Опубликована: Фев. 27, 2024

Optical biosensors are the devices converting biological signals into light for quantitative and classification detection. In recent years, metasurfaces combined with terahertz (THz) time-domain spectroscopy have been applied in various biosensing field, such as medical sensing food monitoring. However, current meta-sensors face problems of complex structures insufficient sensitivity, target molecules categories limited. Therefore, we proposed a meta-sensor both reliable fabrication, simple structure, high performance. Here, metasurface is fabricated on rigid flexible film, effect substrate performance first time to be discussed experimentally. We established novel relationship between analyte [cancer cell, doxycycline hydrochloride (DCH)] resonance, results comprehensive well-performed. experiments, an obvious frequency shift 110 GHz occurs when DCH concentration increased from 0.1 16 mg/mL, practical sensitivity reaches up 166.67 kHz $\cdot $ mm2/cell human prostatic cancer cell DU-145 116.67 bladder 5637, respectively. The meta-sensor, advantages no-label, notation="LaTeX">${Q}$ -factor, performance, not only validates effectiveness refractive index but also provides significant reference high-performance THz sensors applications.

Язык: Английский

Highly Responsive Graphene-Integrated Metasurface Surface Plasmon Resonance Sensor Augmented with Ag-Au-SiO₂ Nanostructures and Machine Learning for Advanced Biomedical Diagnostics DOI
Jacob Wekalao, Abdulkarem H. M. Almawgani,

Refka Ghodhbani

и другие.

Plasmonics, Год журнала: 2025, Номер unknown

Опубликована: Июнь 3, 2025

Язык: Английский

Процитировано

0
Urinary Metabolic Biomarker Profiling for Cancer Diagnosis by Terahertz Spectroscopy: Review and Perspective DOI Creative Commons
Andreja Abina,

Tjaša Korošec,

Uroš Puc

и другие.

Photonics, Год журнала: 2023, Номер 10(9), С. 1051 - 1051

Опубликована: Сен. 15, 2023

In the last decade, terahertz (THz) technologies have been introduced to detection, identification, and quantification of biomolecules in various biological samples. This review focuses on substances that represent important biomarkers urine associated with cancers their treatments. From a diagnostic point view, liquid biopsy is particularly because it allows non-invasive rapid collection large volumes this review, THz spectral responses considered metabolic obtained previous studies are collected. addition, findings from relatively small number prior already carried out samples summarised. context, we also present different methods used for analysis. Finally, brief discussion given, presenting perspectives future research field, interpreted based results studies. work provides information further application techniques biomedicine detecting monitoring urinary diseases, including cancer.

Язык: Английский

Процитировано

7
High-Sensitivity Terahertz Biosensor Based on Plasmon-Induced Transparency Metamaterials DOI Creative Commons

Mengcheng Guan,

Xu Sun, Wei Jiang

и другие.

Photonics, Год журнала: 2023, Номер 10(11), С. 1258 - 1258

Опубликована: Ноя. 14, 2023

This paper presents a metamaterial biosensor composed of dual-cut wires (DCWs) and quadruple split-ring resonators (QSRs), achieving polarization-independent plasmon-induced transparency (PIT) effects in the terahertz range. By leveraging coupling between bright dark modes, we observe transparent window with minimal loss at 1.22 THz. We investigate physical mechanism PIT effect by analyzing surface current distribution electric fields. Simulations reveal that shows peak shift up to 146.7 GHz an analyte thickness 14 μm. Moreover, as refractive index increases from 1.0 1.6, biosensor’s theoretical sensitivity is calculated be 281.25 GHz/RIU. Furthermore, explore application proposed DCW/QSR for detection bacteriophage viruses. Our simulation results demonstrate serves effective sensing platform detecting viruses such PRD1 MS2. These findings underscore potential our high-sensitivity biosensor, which holds great promise field biosensing, offering practical cost-effective approach label-free biomedical detection.

Язык: Английский

Процитировано

6
Design of tunable ultra-wideband metasurface absorber with pixelated checkerboard pattern based on BGWO DOI Creative Commons
Yaxi Pan, Jian Dong, Meng Wang

и другие.

Results in Physics, Год журнала: 2024, Номер 57, С. 107376 - 107376

Опубликована: Янв. 23, 2024

In this paper, a tunable ultra-wideband terahertz (THz) metasurface absorber utilizing vanadium dioxide (VO2) has been designed with the assistance of Binary Grey Wolf Optimization algorithm. The electromagnetic absorption characteristics and physical mechanism proposed are modeled numerically simulated based on wave interference cancellation theory impedance matching theory. Further discussion field distributions is undertaken to elucidate underlying mechanisms absorber. Remarkably, achieves rates exceeding 90% within frequency range 2.83 8.46 THz. Through manipulation VO2 conductivity, allows dynamic amplitude adjustment ranging from 1.2% 97%. Compared previous studies, exhibits substantial advantages in terms bandwidth, polarization insensitivity, wide-angle absorption. Its potential applications encompass modulators, cloaking devices, chemical energy absorption, other domains. structure design methodology can provide valuable references for investigation novel multifunctional devices.

Язык: Английский

Процитировано

2
Meta-Biosensor With High Q-Factor Based on Wet Etching for Terahertz Detection DOI
Xueer Chen, Longfang Ye, Daquan Yu

и другие.

IEEE Sensors Journal, Год журнала: 2024, Номер 24(7), С. 9989 - 9997

Опубликована: Фев. 27, 2024

Optical biosensors are the devices converting biological signals into light for quantitative and classification detection. In recent years, metasurfaces combined with terahertz (THz) time-domain spectroscopy have been applied in various biosensing field, such as medical sensing food monitoring. However, current meta-sensors face problems of complex structures insufficient sensitivity, target molecules categories limited. Therefore, we proposed a meta-sensor both reliable fabrication, simple structure, high performance. Here, metasurface is fabricated on rigid flexible film, effect substrate performance first time to be discussed experimentally. We established novel relationship between analyte [cancer cell, doxycycline hydrochloride (DCH)] resonance, results comprehensive well-performed. experiments, an obvious frequency shift 110 GHz occurs when DCH concentration increased from 0.1 16 mg/mL, practical sensitivity reaches up 166.67 kHz $\cdot $ mm2/cell human prostatic cancer cell DU-145 116.67 bladder 5637, respectively. The meta-sensor, advantages no-label, notation="LaTeX">${Q}$ -factor, performance, not only validates effectiveness refractive index but also provides significant reference high-performance THz sensors applications.

Язык: Английский

Процитировано

2