Journal of Pharmaceutical and Biomedical Analysis Open,
Год журнала:
2024,
Номер
4, С. 100037 - 100037
Опубликована: Авг. 8, 2024
The
biomedicine
scientific
field
has
made
continuous
progress,
introducing
various
pharmaceutical
compounds
to
enhance
human
life.
While
these
advancements
bring
benefits,
the
unregulated
use
of
raises
concerns,
particularly
regarding
their
presence
in
environment
and
potential
adverse
effects
on
health.
Therefore,
assessment
by
analytical
strategies
is
imperative
for
comprehending
appraising
interactions
across
diverse
matrices.
In
this
sense,
solid-based
microextraction
procedures
have
shed
light
challenging
task
evaluating
complex
samples.
Moreover,
miniaturized
are
firmly
rooted
principles
green
chemistry,
thereby
presenting
more
environmentally
friendly
approaches
than
traditional
extraction
methods.
Consequently,
significant
endeavors
been
undertaken
introduce
novel
sorbent
materials
that
foster
a
selective
interaction
with
target
analytes.
Having
mind,
molecularly
imprinted
polymers
(MIPs)
emerge
as
solution,
providing
binding
sites
capable
interacting
analyte
within
sample.
integration
MIPs
phases
led
strides
advancing
evaluation
different
Hence,
review
offer
comprehensive
overview
current
applications
combined
ABSTRACT
Capillary
electrophoresis
(CE)
is
a
powerful
analysis
technique
with
advantages
such
as
high
separation
efficiency
resolution
factors
above
1.5,
low
sample
consumption
of
less
than
10
µL,
cost‐effectiveness,
and
eco‐friendliness
reduced
solvent
use
lower
operational
costs.
However,
CE
also
faces
limitations,
including
limited
detection
sensitivity
for
low‐concentration
samples
interference
from
complex
biological
matrices.
Prior
to
performing
CE,
it
common
utilize
preparation
procedures
solid‐phase
microextraction
(SPME)
liquid‐phase
(LPME)
in
order
improve
the
selectivity
analysis.
Recently,
there
have
been
advancements
development
novel
materials
that
potential
greatly
enhance
performance
SPME
LPME.
This
review
examines
various
their
uses
when
combined
CE.
These
include
carbon
nanotubes,
covalent
organic
frameworks,
metal–organic
graphene
its
derivatives,
molecularly
imprinted
polymers,
layered
double
hydroxides,
ionic
liquids,
deep
eutectic
solvents.
The
utilization
these
innovative
extraction
methods
being
examined.
Analyte
recoveries
limits
attained
range
matrices
are
used
assess
effects
on
selectivity,
sensitivity,
efficiency.
Exploring
new
techniques
important
enables
researchers
address
current
limitations
has
efficiency,
thereby
improving
